Success Metrics

Clinical Success Rate
68.4%

Based on 13 completed trials

Completion Rate
68%(13/19)
Active Trials
22(49%)
Results Posted
123%(16 trials)
Terminated
6(13%)

Phase Distribution

Ph phase_3
5
11%
Ph phase_1
13
29%
Ph not_applicable
1
2%
Ph phase_2
20
44%
Ph phase_4
1
2%

Phase Distribution

13

Early Stage

20

Mid Stage

6

Late Stage

Phase Distribution40 total trials
Phase 1Safety & dosage
13(32.5%)
Phase 2Efficacy & side effects
20(50.0%)
Phase 3Large-scale testing
5(12.5%)
Phase 4Post-market surveillance
1(2.5%)
N/ANon-phased studies
1(2.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

65.0%

13 of 20 finished

Non-Completion Rate

35.0%

7 ended early

Currently Active

22

trials recruiting

Total Trials

45

all time

Status Distribution
Active(22)
Completed(13)
Terminated(7)
Other(3)

Detailed Status

Recruiting15
Completed13
Active, not recruiting7
Terminated6
unknown3
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
45
Active
22
Success Rate
68.4%
Most Advanced
Phase 4

Trials by Phase

Phase 113 (32.5%)
Phase 220 (50.0%)
Phase 35 (12.5%)
Phase 41 (2.5%)
N/A1 (2.5%)

Trials by Status

completed1329%
recruiting1533%
active_not_recruiting716%
terminated613%
unknown37%
withdrawn12%

Recent Activity

Clinical Trials (45)

Showing 20 of 45 trialsScroll for more
NCT02981628Phase 2

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT05645718Phase 2

Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia

Recruiting
NCT03488225Phase 2

Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia

Terminated
NCT03739814Phase 2

Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

Recruiting
NCT07493161Not Applicable

Chemotherapy With Targeted-Immunotherapy for Newly Diagnosed Ph+ ALL

Recruiting
NCT03959085Phase 3

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

Recruiting
NCT01371630Phase 1

Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia

Recruiting
NCT03441061Phase 2

Inotuzumab Ozogamicin in Treating Patients With B-cell Acute Lymphocytic Leukemia With Positive Minimal Residual Disease

Active Not Recruiting
NCT05303792Phase 2

Comparing Inotuzumab Combined With Low Intensity Chemotherapy Plus Blinatumomab to Usual Chemotherapy Plus Blinatumomab in Older Adults With CD22+ B-cell Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT05748171Phase 2

A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO) in Children (1 to <18 Years) With First Relapse ALL

Recruiting
NCT03150693Phase 3

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Recruiting
NCT04747912Phase 2

Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)

Recruiting
NCT02877303Phase 2

Blinatumomab, Inotuzumab Ozogamicin, and Combination Chemotherapy as Frontline Therapy in Treating Patients With B Acute Lymphoblastic Leukemia

Recruiting
NCT06287229Phase 1

Phase Ib/II Study Assessing the Clinical Activity and Safety of Brexucabtagene Autoleucel as a Consolidation in Patients With Relapsed/Refractory (R/R) and Newly Diagnosed B-cell Acute Lymphocytic Leukemia (ALL) Post Cytoreduction With Mini-HCVD-inotuzumab-blinatumomab/HCVAD-inotuzumab-blinatumomab

Recruiting
NCT05456698Phase 2

Efficacy and Safety of Inotuzumab Ozogamicin in Treating Adult Patients With Ph Negative ALL With Minimal Residual Disease Positive After Induction Chemotherapy

Active Not Recruiting
NCT03856216Phase 2

Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation

Terminated
NCT01679119Phase 2

Treatment of Patients With Diffuse Large B Cell Lymphoma Who Are Not Suitable for Anthracycline Containing Chemotherapy

Completed
NCT03913559Phase 2

Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia

Terminated
NCT05016947Phase 1

Venetoclax Plus Inotuzumab for B-ALL

Active Not Recruiting
NCT04307134

Besponsa Post Marketing Surveillance Study

Completed

Drug Details

Intervention Type
DRUG
Total Trials
45