Success Metrics

Clinical Success Rate
87.0%

Based on 20 completed trials

Completion Rate
87%(20/23)
Active Trials
1(3%)
Results Posted
20%(4 trials)
Terminated
3(9%)

Phase Distribution

Ph early_phase_1
1
3%
Ph phase_1
6
18%
Ph phase_2
10
29%
Ph phase_3
6
18%
Ph phase_4
3
9%
Ph not_applicable
6
18%

Phase Distribution

7

Early Stage

10

Mid Stage

9

Late Stage

Phase Distribution32 total trials
Early Phase 1First-in-human
1(3.1%)
Phase 1Safety & dosage
6(18.8%)
Phase 2Efficacy & side effects
10(31.3%)
Phase 3Large-scale testing
6(18.8%)
Phase 4Post-market surveillance
3(9.4%)
N/ANon-phased studies
6(18.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.1%

20 of 27 finished

Non-Completion Rate

25.9%

7 ended early

Currently Active

1

trials recruiting

Total Trials

34

all time

Status Distribution
Active(2)
Completed(20)
Terminated(7)
Other(5)

Detailed Status

Completed20
unknown5
Withdrawn4
Terminated3
Recruiting1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
34
Active
1
Success Rate
87.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (3.1%)
Phase 16 (18.8%)
Phase 210 (31.3%)
Phase 36 (18.8%)
Phase 43 (9.4%)
N/A6 (18.8%)

Trials by Status

recruiting13%
not_yet_recruiting13%
unknown515%
completed2059%
terminated39%
withdrawn412%

Recent Activity

Clinical Trials (34)

Showing 20 of 34 trialsScroll for more
NCT07498309Phase 3

Evaluation of the Efficacy of Iloprost in the Management of Vaso-occlusive Crises in Adult Patients With Sickle Cell Disease

Not Yet Recruiting
NCT06319274Phase 2

Infusion of Prostacyclin vs Placebo for 72-hours in Mechanically Ventilated Patients With Acute Respiratory Failure

Recruiting
NCT03788837Phase 3

ILOPROST in Septic Shock With Persistent Microperfusion Defects (I-MICRO)

Completed
NCT05411107Phase 2

Oral Iloprost for the Prevention of Lung Cancer In Former Smokers

Withdrawn
NCT03903939Phase 2

Infusion of Prostacyclin vs Placebo for 72-hours in Trauma Patients With Haemorrhagic Shock Suffering From Organ Failure

Completed
NCT04420741Phase 2

Infusion of Prostacyclin (Iloprost) vs Placebo for 72-hours in COVID-19 Patients With Respiratory Failure

Completed
NCT04123444Phase 2

Infusion of Prostacyclin (Iloprost) vs Placebo for 72-hours in Patients With Septic Shock Suffering From Organ Failure

Completed
NCT00561223Not Applicable

Iloprost in Gas Exchange/Pulm Mechanics in Chronic Obstructive Pulmonary Disease (COPD)

Completed
NCT02237183Phase 1

Iloprost in Preventing Lung Cancer in Former Smokers

Completed
NCT03111212Phase 3

Iloprost in Acute Respiratory Distress Syndrome

Completed
NCT02685618Phase 2

Endothelial Dysfunction in Resuscitated Cardiac Arrest

Completed
NCT04598191Not Applicable

Effect of Intraoperative Iloprost Inhalant on Hemodynamic Stability in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery

Unknown
NCT00084409Phase 2

Iloprost in Preventing Lung Cancer in Patients at High Risk for This Disease

Completed
NCT03620526Phase 4

Inhaled Iloprost and Exercise Hemodynamics and Ventricular Performance in Heart Failure With Preserved Ejection Fraction

Unknown
NCT01054105

Effect of BMPR-2 Gene Mutations on Hemodynamic Response by Iloprost Inhalation in Pulmonary Arterial Hypertension

Completed
NCT03365479Not Applicable

Acute Response of Iloprost Inhalation Using the Breelib Nebulizer in Pulmonary Arterial Hypertension

Completed
NCT02784899Not Applicable

Effect of Iloprost on Pulmonary Oxygenation in Patients With Low Diffusing Capacity During One-lung Ventilation

Completed
NCT01437878Phase 2

Effects of Ventavis in Patients With Pulmonary Hypertension (PH) Secondary to Chronic Obstructive Pulmonary Disease (COPD)

Terminated
NCT00709098Phase 3

Safety Study Extension of Iloprost Power 15 in Pulmonary Arterial Hypertension

Completed
NCT00724321Phase 1

Effects of Iloprost on Hypoxic Pulmonary Vasoconstriction at Altitude

Withdrawn

Drug Details

Intervention Type
DRUG
Total Trials
34