Success Metrics

Clinical Success Rate
87.3%

Based on 103 completed trials

Completion Rate
87%(103/118)
Active Trials
23(13%)
Results Posted
45%(46 trials)
Terminated
15(8%)

Phase Distribution

Ph early_phase_1
1
1%
Ph not_applicable
5
3%
Ph phase_2
69
38%
Ph phase_3
40
22%
Ph phase_4
9
5%
Ph phase_1
56
31%

Phase Distribution

57

Early Stage

69

Mid Stage

49

Late Stage

Phase Distribution180 total trials
Early Phase 1First-in-human
1(0.6%)
Phase 1Safety & dosage
56(31.1%)
Phase 2Efficacy & side effects
69(38.3%)
Phase 3Large-scale testing
40(22.2%)
Phase 4Post-market surveillance
9(5.0%)
N/ANon-phased studies
5(2.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

82.4%

103 of 125 finished

Non-Completion Rate

17.6%

22 ended early

Currently Active

23

trials recruiting

Total Trials

181

all time

Status Distribution
Active(26)
Completed(103)
Terminated(22)
Other(30)

Detailed Status

Completed103
unknown30
Terminated15
Recruiting14
Active, not recruiting9
Withdrawn7

Development Timeline

Analytics

Development Status

Total Trials
181
Active
23
Success Rate
87.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.6%)
Phase 156 (31.1%)
Phase 269 (38.3%)
Phase 340 (22.2%)
Phase 49 (5.0%)
N/A5 (2.8%)

Trials by Status

unknown3017%
completed10357%
not_yet_recruiting32%
withdrawn74%
active_not_recruiting95%
recruiting148%
terminated158%

Recent Activity

Clinical Trials (181)

Showing 20 of 181 trialsScroll for more
NCT07131059Not Applicable

MRD-positive AML Clinical Study

Recruiting
NCT06744504Phase 3

Standard-dose vs Intermediate-dose Cytarabine Induction in the Treatment of Acute Myeloid Leukemia With RUNX1-RUNX1T1

Recruiting
NCT06034470Phase 1

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

Active Not Recruiting
NCT07046078Phase 2

Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer

Recruiting
NCT02416388Phase 2

Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR

Recruiting
NCT07228273Phase 2

Induction and Consolidation With Fludarabine, Cytarabine, Idarubicin, and Venetoclax for the Treatment of Acute Myeloid Leukemia

Recruiting
NCT03117751Phase 2

Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

Active Not Recruiting
NCT04047641Phase 1

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Recruiting
NCT07604233Phase 1

Phase 1/2 FLAG-IDA, VEN and Asciminib in CML and Ph+ AML

Not Yet Recruiting
NCT03330821Phase 1

Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

Active Not Recruiting
NCT04250051Phase 1

Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia

Terminated
NCT02688140Phase 3

Study for Patients With Newly Diagnosed, High-risk Acute Promyelocytic Leukemia

Completed
NCT02632708Phase 1

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

Active Not Recruiting
NCT03589729Phase 2

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

Recruiting
NCT02115295Phase 2

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

Recruiting
NCT06928662Phase 1

Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse

Recruiting
NCT06744556Phase 2

HAV Versus DAV/IAV Induction Regimen in Elderly Patients With AML

Active Not Recruiting
NCT04801797Phase 2

Venetoclax + Azacitidine vs. Induction Chemotherapy in AML

Active Not Recruiting
NCT03164057Phase 2

A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

Active Not Recruiting
NCT06001788Phase 1

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
181