Success Metrics

Clinical Success Rate
88.0%

Based on 103 completed trials

Completion Rate
88%(103/117)
Active Trials
23(13%)
Results Posted
45%(46 trials)
Terminated
14(8%)

Phase Distribution

Ph phase_4
9
5%
Ph phase_2
69
39%
Ph not_applicable
5
3%
Ph phase_1
54
30%
Ph early_phase_1
1
1%
Ph phase_3
40
22%

Phase Distribution

55

Early Stage

69

Mid Stage

49

Late Stage

Phase Distribution178 total trials
Early Phase 1First-in-human
1(0.6%)
Phase 1Safety & dosage
54(30.3%)
Phase 2Efficacy & side effects
69(38.8%)
Phase 3Large-scale testing
40(22.5%)
Phase 4Post-market surveillance
9(5.1%)
N/ANon-phased studies
5(2.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

83.1%

103 of 124 finished

Non-Completion Rate

16.9%

21 ended early

Currently Active

23

trials recruiting

Total Trials

179

all time

Status Distribution
Active(25)
Completed(103)
Terminated(21)
Other(30)

Detailed Status

Completed103
unknown30
Recruiting16
Terminated14
Active, not recruiting7
Withdrawn7

Development Timeline

Analytics

Development Status

Total Trials
179
Active
23
Success Rate
88.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.6%)
Phase 154 (30.3%)
Phase 269 (38.8%)
Phase 340 (22.5%)
Phase 49 (5.1%)
N/A5 (2.8%)

Trials by Status

active_not_recruiting74%
not_yet_recruiting21%
terminated148%
completed10358%
unknown3017%
withdrawn74%
recruiting169%

Recent Activity

Clinical Trials (179)

Showing 20 of 179 trialsScroll for more
NCT03164057Phase 2

A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

Active Not Recruiting
NCT06034470Phase 1

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

Active Not Recruiting
NCT06001788Phase 1

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Recruiting
NCT03250338Phase 3

Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML

Completed
NCT00801489Phase 2

Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Recruiting
NCT06744504Phase 3

Standard-dose vs Intermediate-dose Cytarabine Induction in the Treatment of Acute Myeloid Leukemia With RUNX1-RUNX1T1

Recruiting
NCT04107727Phase 2

Trial to Compare Efficacy and Safety of Chemotherapy/Quizartinib vs Chemotherapy/Placebo in Adults FMS-like Tyrosine Kinase 3 (FLT3) Wild-type Acute Myeloid Leukemia (AML)

Completed
NCT07486479Phase 3

Venetoclax, Azacitidine, and Mitoxantrone Hydrochloride Liposome Versus Idarubicin and Cytarabine in Newly Diagnosed AML

Not Yet Recruiting
NCT03226418Phase 2

Geriatric Assessment & Genetic Profiling to Personalize Therapy in Older Adults With Acute Myeloid Leukemia

Completed
NCT04375631Phase 1

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Recruiting
NCT03214562Phase 1

Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia

Recruiting
NCT02339740Phase 3

Tretinoin and Arsenic Trioxide in Treating Patients With Untreated Acute Promyelocytic Leukemia

Active Not Recruiting
NCT07046078Phase 2

Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer

Recruiting
NCT07228273Phase 2

Induction and Consolidation With Fludarabine, Cytarabine, Idarubicin, and Venetoclax for the Treatment of Acute Myeloid Leukemia

Recruiting
NCT03926624Phase 3

Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage

Terminated
NCT04047641Phase 1

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Recruiting
NCT02881086Phase 3

Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment

Completed
NCT03117751Phase 2

Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

Active Not Recruiting
NCT03330821Phase 1

Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

Active Not Recruiting
NCT00534469Phase 2

Auto BMT for Non-M3 AML in 1st Remission in Pts </=60y of Age Using Busulfan/FTBI & VP16 as a Prep R

Completed

Drug Details

Intervention Type
DRUG
Total Trials
179