Success Metrics

Clinical Success Rate
93.8%

Based on 15 completed trials

Completion Rate
94%(15/16)
Active Trials
3(5%)
Results Posted
13%(2 trials)
Terminated
1(2%)

Phase Distribution

Ph phase_4
8
13%
Ph phase_2
35
56%
Ph not_applicable
2
3%
Ph phase_3
12
19%
Ph phase_1
5
8%

Phase Distribution

5

Early Stage

35

Mid Stage

20

Late Stage

Phase Distribution62 total trials
Phase 1Safety & dosage
5(8.1%)
Phase 2Efficacy & side effects
35(56.5%)
Phase 3Large-scale testing
12(19.4%)
Phase 4Post-market surveillance
8(12.9%)
N/ANon-phased studies
2(3.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

93.8%

15 of 16 finished

Non-Completion Rate

6.3%

1 ended early

Currently Active

3

trials recruiting

Total Trials

63

all time

Status Distribution
Active(5)
Completed(15)
Terminated(1)
Other(42)

Detailed Status

unknown41
Completed15
Not yet recruiting2
Recruiting2
Active, not recruiting1
Suspended1

Development Timeline

Analytics

Development Status

Total Trials
63
Active
3
Success Rate
93.8%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (8.1%)
Phase 235 (56.5%)
Phase 312 (19.4%)
Phase 48 (12.9%)
N/A2 (3.2%)

Trials by Status

unknown4165%
active_not_recruiting12%
not_yet_recruiting23%
recruiting23%
suspended12%
completed1524%
terminated12%

Recent Activity

Clinical Trials (63)

Showing 20 of 63 trialsScroll for more
NCT05263947Phase 2

Bevacizumab Combined With Double Doses of Icotinib in Advanced NSCLC Patients With EGFR L858R Mutation

Completed
NCT06955325Phase 3

Umbrella Trial of Adjuvant Therapy in Completely Resected High-risk Stage IA-IB NSCLC: Focus on Driver Mutations

Not Yet Recruiting
NCT02264210Phase 2

Icotinib for Completed Resected IB NSCLC With EGFR Mutation

Completed
NCT05007938Phase 2

Befotertinib and Icotinib in Treatment-naive Patients With Advanced EGFR-Mutant Lung Cancer

Active Not Recruiting
NCT06517953Phase 2

Befotertinib and Icotinib for NSCLC With Uncommon EGFR Mutations

Recruiting
NCT05514314Phase 2

A Multicenter Prospective Study to Assess the Effects of Adjuvant Icotinib in EGFRm Stage I NSCLC With High-risk of Disease Recurrence After Complete Resection

Unknown
NCT02044328Phase 2

Icotinib as an Adjuvant Therapy for Patients With Stage IIA-IIIA Adenocarcinoma With EGFR Mutation

Completed
NCT05132985Phase 2

Neoadjuvant Icotinib With Chemotherapy for Epidermal Growth Factor Receptor(EGFR)-Mutated Resectable Lung Adenocarcinoma

Not Yet Recruiting
NCT05104788Phase 2

A Study of Icotinib With Chemotherapy as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung Cancer

Recruiting
NCT02934256Phase 2

Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors

Completed
NCT02448797Phase 3

Icotinib as Adjuvant Therapy Compared With Standard Chemotherapy in Stage II-IIIA NSCLC With EGFR-mutation

Unknown
NCT04797806Phase 3

Study of Anlotinib Combined With Icotinib as the First-line Treatment in Patients With EGFR Concomitant Mutation NSCLC

Unknown
NCT02362230Phase 2

Evaluation of Icotinib in Metastatic Triple-negative Breast Cancer After Second-line Therapy

Terminated
NCT04575415

Bevacizumab Plus EGFR-TKIs in Chinese Patients With EGFR-mutant NSCLC: a Real-world Study

Unknown
NCT02737774Phase 2

Alternating Icotinib and Chemotherapy for Advanced Non-small Cell Lung Cancer With EGFR Mutation

Unknown
NCT02744664Phase 4

Cryotherapy Combine Icotinib for Advanced NSCLC Treatment

Completed
NCT04058704Phase 3

A Study to Determine the Efficiency For Brain Metastasis NSCLC Patients Treated With Icotinib Alone or Combined With Radiation Therapy

Unknown
NCT01855854Phase 2

Second-line Treatment With Icotinib in Esophageal Carcinoma Patients With EGFR Overexpression (IHC 3+) or Positive FISH

Completed
NCT01719536Phase 3

Icotinib Versus First-line Chemotherapy Plus Maintenance Treatment in EGFR Positive Lung Adenocarcinoma Patients

Completed
NCT03992885Phase 3

Clinical Study of Combination Therapy With Ectiecinib, Pemetrexed and Platinum in Patients With Metastatic Non-squamous Non-small Cell Lung Cancer With EGFR Mutations.

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
63