Success Metrics

Clinical Success Rate
82.4%

Based on 89 completed trials

Completion Rate
82%(89/108)
Active Trials
20(13%)
Results Posted
43%(38 trials)
Terminated
19(13%)

Phase Distribution

Ph not_applicable
13
9%
Ph phase_1
31
21%
Ph phase_3
30
20%
Ph early_phase_1
3
2%
Ph phase_2
63
42%
Ph phase_4
5
3%

Phase Distribution

34

Early Stage

63

Mid Stage

35

Late Stage

Phase Distribution145 total trials
Early Phase 1First-in-human
3(2.1%)
Phase 1Safety & dosage
31(21.4%)
Phase 2Efficacy & side effects
63(43.4%)
Phase 3Large-scale testing
30(20.7%)
Phase 4Post-market surveillance
5(3.4%)
N/ANon-phased studies
13(9.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

78.1%

89 of 114 finished

Non-Completion Rate

21.9%

25 ended early

Currently Active

20

trials recruiting

Total Trials

151

all time

Status Distribution
Active(23)
Completed(89)
Terminated(25)
Other(14)

Detailed Status

Completed89
Terminated19
unknown14
Recruiting12
Active, not recruiting8
Withdrawn6

Development Timeline

Analytics

Development Status

Total Trials
151
Active
20
Success Rate
82.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (2.1%)
Phase 131 (21.4%)
Phase 263 (43.4%)
Phase 330 (20.7%)
Phase 45 (3.4%)
N/A13 (9.0%)

Trials by Status

unknown149%
active_not_recruiting85%
terminated1913%
not_yet_recruiting21%
enrolling_by_invitation11%
recruiting128%
withdrawn64%
completed8959%

Recent Activity

Clinical Trials (151)

Showing 20 of 151 trialsScroll for more
NCT06456346Phase 3

Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)

Recruiting
NCT05662098Early Phase 1

Alternative Dosing And Prevention of Transfusions (ADAPT)

Active Not Recruiting
NCT07507760Phase 2

Oral Decitabine Plus Ivosidenib as First Line for Older/Unfit Adult AML Patients

Not Yet Recruiting
NCT06093672Phase 3

Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera

Recruiting
NCT06871410Phase 1

Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Recruiting
NCT06930352Phase 2

Ziftomenib for the Treatment of Patients With NPM1 Mutated or KMT2A Rearranged Acute Myeloid Leukemia Not Eligible for Standard Therapy

Not Yet Recruiting
NCT05357482Phase 1

Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia

Active Not Recruiting
NCT05853458Phase 4

Evaluation of HU-resistance in Adult Patients With Polycythemia Vera Who Meet PV-AIM Predictors

Terminated
NCT06063317Phase 1

A Study of onCARlytics (CF33-CD19) in Combination With Blinatumomab in Adults With Advanced or Metastatic Solid Tumors (OASIS)

Terminated
NCT07033598Phase 2

Pacritinib vs. Hydroxyurea in Advanced Proliferative Chronic Myelomonocytic Leukemia

Recruiting
NCT06526117Phase 4

Stroke Prevention in Nigeria 2 Trial

Recruiting
NCT05526924Phase 1

Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With Previously Treated Head and Neck Cancer

Recruiting
NCT03511118

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Recruiting
NCT04217356

Study of Stem Cell Transplant vs. Non-Transplant Therapies in High-Risk Myelofibrosis

Active Not Recruiting
NCT03500731Phase 1

Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure

Recruiting
NCT05451940Phase 1

Hydroxyurea and EPO in Sickle Cell Disease

Completed
NCT01962415Phase 2

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Recruiting
NCT05953584Phase 2

A Phase 2 Open-label Study to Evaluate the Activity of Etavopivat on Transcranial Doppler Velocities in Pediatric Patients With Sickle Cell Disease Who Are at Increased Risk for Primary Stroke

Recruiting
NCT03860844Phase 2

Isatuximab in Combination With Chemotherapy in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

Terminated
NCT05548062

Study to Identify and Describe Predictive Factors for Thromboembolic Events in Patients With High-risk Polycythemia Vera

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
151