Success Metrics

Clinical Success Rate
100.0%

Based on 15 completed trials

Completion Rate
100%(15/15)
Active Trials
0(0%)
Results Posted
60%(9 trials)

Phase Distribution

Ph phase_3
4
24%
Ph phase_2
9
53%
Ph phase_4
4
24%

Phase Distribution

0

Early Stage

9

Mid Stage

8

Late Stage

Phase Distribution17 total trials
Phase 2Efficacy & side effects
9(52.9%)
Phase 3Large-scale testing
4(23.5%)
Phase 4Post-market surveillance
4(23.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

93.8%

15 of 16 finished

Non-Completion Rate

6.3%

1 ended early

Currently Active

0

trials recruiting

Total Trials

17

all time

Status Distribution
Completed(15)
Terminated(1)
Other(1)

Detailed Status

Completed15
Withdrawn1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
17
Active
0
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Phase 29 (52.9%)
Phase 34 (23.5%)
Phase 44 (23.5%)

Trials by Status

withdrawn16%
unknown16%
completed1588%

Recent Activity

0 active trials
Showing 5 of 17
completedphase_3

Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen

NCT03974932
completedphase_2

Phase 2 Bunionectomy HTX-011 Administration Study

NCT03718039
completedphase_2

Phase 2B Upper Extremity Nerve Block Study

NCT03011333
completedphase_3

Bunionectomy Study for Postoperative Analgesia (EPOCH 1)

NCT03295721
completedphase_2

Pilot Herniorrhaphy Study for Postoperative Analgesia

NCT02504580
View all 17 trials

Clinical Trials (17)

Showing 17 of 17 trials
NCT03974932Phase 3

Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen

Completed
NCT03718039Phase 2

Phase 2 Bunionectomy HTX-011 Administration Study

Completed
NCT03011333Phase 2

Phase 2B Upper Extremity Nerve Block Study

Completed
NCT03295721Phase 3

Bunionectomy Study for Postoperative Analgesia (EPOCH 1)

Completed
NCT02504580Phase 2

Pilot Herniorrhaphy Study for Postoperative Analgesia

Completed
NCT03015532Phase 2

Total Knee Arthroplasty Infiltration Study for Postoperative Analgesia

Completed
NCT03237481Phase 3

Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)

Completed
NCT03695367Phase 2

Phase 2 Herniorrhaphy Study for Opioid Elimination

Completed
NCT05188053Phase 4

Periarticular Bupivacaine + Meloxicam ER Solution Versus Standard Practice During Total Knee Arthroplasty

Completed
NCT06109428Phase 4

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE

Completed
NCT06109415Phase 4

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE.

Completed
NCT05109312Phase 4

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.

Unknown
NCT04911062Phase 2

HTX-011 in Spinal Surgery

Completed
NCT03922048Phase 2

Pediatric Postoperative Analgesia Herniorrhaphy Study

Withdrawn
NCT03955211Phase 2

HTX-011 Administration Study in Planned Caesarean Section Procedure

Completed
NCT03907176Phase 3

Herniorrhaphy Study for Opioid Elimination

Completed
NCT02471898Phase 2

A Phase 2, Two-Part Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy

Completed

All 17 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
17