Success Metrics

Clinical Success Rate
100.0%

Based on 27 completed trials

Completion Rate
100%(27/27)
Active Trials
0(0%)
Results Posted
15%(4 trials)

Phase Distribution

Ph phase_2
5
18%
Ph phase_1
15
54%
Ph phase_3
8
29%

Phase Distribution

15

Early Stage

5

Mid Stage

8

Late Stage

Phase Distribution28 total trials
Phase 1Safety & dosage
15(53.6%)
Phase 2Efficacy & side effects
5(17.9%)
Phase 3Large-scale testing
8(28.6%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

96.4%

27 of 28 finished

Non-Completion Rate

3.6%

1 ended early

Currently Active

0

trials recruiting

Total Trials

28

all time

Status Distribution
Completed(27)
Terminated(1)

Detailed Status

Completed27
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
28
Active
0
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 115 (53.6%)
Phase 25 (17.9%)
Phase 38 (28.6%)

Trials by Status

withdrawn14%
completed2796%

Recent Activity

Clinical Trials (28)

Showing 20 of 28 trialsScroll for more
NCT07404306Phase 1

Part 1: Dose-Finding of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users

Completed
NCT06795204Phase 1

Effects of HSK3486 on Cardiac Repolarization in Health Subjects (TQT)

Completed
NCT05486416Phase 3

Safety and Efficacy of HSK3486 Compared to Propofol for Induction of General Anesthesia in Adults With Elective Surgery

Completed
NCT04711837Phase 3

Efficacy and Safety of HSK3486 Compared to Propofol in Induction of General Anesthesia in Adults Having Elective Surgery

Completed
NCT05478174Phase 3

Efficacy and Safety of HSK3486 Compared to Propofol for Adults Undergoing Elective Surgery With General Anesthesia

Completed
NCT05614544Phase 1

Dose-Finding and Human Abuse Potential Study Of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users

Completed
NCT03751969Phase 1

A Study Evaluating the Mass Balance of Micro-dose[14C]HSK3486 Emulsion Injection in Healthy Adults

Withdrawn
NCT04511728Phase 3

A Study to Evaluate the Efficacy and Safety of HSK3486 in the Induction of General Anesthesia

Completed
NCT04620031Phase 3

A Study Evaluating Sedation of Intravenous Administration of HSK3486 Injectable Emulsion in ICU Patients Undergoing Mechanical Ventilation

Completed
NCT04669821Phase 2

A Clinical Study Evaluating Sedation of Intravenous Administration of HSK3486 in ICU Patients Undergoing Long-Term Mechanical Ventilation

Completed
NCT04029766Phase 1

A Study Evaluating Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of HSK3486 Single Bolus Dose Followed With a 30 Minute Constant Infusion in Healthy Male Subjects

Completed
NCT04142970Phase 1

Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Patients With Impairment Renal Functions

Completed
NCT04145583Phase 1

A Study Evaluating Drug-Drug Interaction (DDI) Between HSK3486 Injectable Emulsion and Voriconazole Tablets

Completed
NCT04111159Phase 3

A Trial Evaluating the Efficacy and Safety of HSK3486 Injectable Emulsion in Subjects Undergoing Fiberoptic Bronchoscopy

Completed
NCT04048811Phase 2

A Clinical Trial Evaluating the Efficacy and Safety of HSK3486 Injectable Emulsion in Elective Surgery Patients

Completed
NCT04197661Phase 1

Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Healthy Elderly Subjects

Completed
NCT04145596Phase 1

Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Patients With Hepatic Impairment

Completed
NCT03773835Phase 1

A Study Evaluating Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of Single IV Dose of HSK3486 Injectable Emulsion in Healthy Subjects.

Completed
NCT03745625Phase 1

A Study Evaluating the Safety and Pharmacokinetics/Pharmacodynamics of HSK3486

Completed
NCT03751956Phase 1

A Study Evaluating the Mass Balance of [14C]HSK3486 Emulsion Injection in Healthy Adults.

Completed

Drug Details

Intervention Type
DRUG
Total Trials
28