Success Metrics

Clinical Success Rate

82.4%

Based on 28 completed trials

Completion Rate

82%(28/34)

Active Trials

0(0%)

Results Posted

39%(11 trials)

Terminated

6(15%)

Phase Distribution

Ph phase_3

22%

Ph phase_4

29%

Ph early_phase_1

Ph phase_1

27%

Ph phase_2

Ph not_applicable

12%

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution41 total trials

Early Phase 1First-in-human

1(2.4%)

Phase 1Safety & dosage

11(26.8%)

Phase 2Efficacy & side effects

3(7.3%)

Phase 3Large-scale testing

9(22.0%)

Phase 4Post-market surveillance

12(29.3%)

N/ANon-phased studies

5(12.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.7%

28 of 38 finished

Non-Completion Rate

26.3%

10 ended early

Currently Active

trials recruiting

Total Trials

all time

Status Distribution

Completed(28)

Terminated(10)

Other(3)

Detailed Status

Completed28

Terminated6

Withdrawn4

unknown3

Development Timeline

Analytics

Development Status

Total Trials

Active

Success Rate

82.4%

Most Advanced

Phase 4

Trials by Phase

Early Phase 11 (2.4%)

Phase 111 (26.8%)

Phase 23 (7.3%)

Phase 39 (22.0%)

Phase 412 (29.3%)

N/A5 (12.2%)

Trials by Status

terminated615%

withdrawn410%

completed2868%

unknown37%

Recent Activity

0 active trials

Showing 5 of 41

completedphase_3

Multicenter Randomized Trial of Non-inferiority Between Glyburide and Insulin for the Treatment of Gestational Diabetes

NCT01731431

completedphase_4

Glyburide vs Placebo as Prophylaxis Against Cerebral Edema in Patients Receiving Radiosurgery for Brain Metastases (RAD 1502/UAB 1593)

NCT02460874

View all 41 trials

Clinical Trials (41)

Showing 20 of 41 trialsScroll for more

NCT01731431Phase 3

Multicenter Randomized Trial of Non-inferiority Between Glyburide and Insulin for the Treatment of Gestational Diabetes

Completed

NCT03029702Phase 4

Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus

Completed

NCT00965991Not Applicable

Metformin Compared to Glyburide in Gestational Diabetes

Completed

NCT01454154Phase 2

Glyburide (RP-1127) for Traumatic Brain Injury (TBI)

Completed

NCT02460874Phase 1

Glyburide vs Placebo as Prophylaxis Against Cerebral Edema in Patients Receiving Radiosurgery for Brain Metastases (RAD 1502/UAB 1593)

Terminated

NCT02524379Phase 1

Spinal Cord Injury Neuroprotection With Glyburide

Terminated

NCT02726490Early Phase 1

Glyburide vs Glucovance in the Treatment of GDM

Terminated

NCT00744965Phase 4

Treatment of Mild Gestational Diabetes With Glyburide Versus Placebo

Completed

NCT03856970Phase 1

Study to Evaluate the Effect of IW-3718 on the Pharmacokinetics of Oral Contraceptive, Levothyroxine, Glyburide, and Digoxin in Healthy Adult Volunteers

Completed

NCT03078725Phase 4

Failure Rate of GLyburide And Metformin Among Gestational Diabetics

Withdrawn

NCT00194896Not Applicable

Preferred Treatment of Type 1.5 Diabetes

Completed

NCT00451620Phase 2

Effect of GlucoNorm vs Glyburide on Post-Prandial Hyperglycemia in Elderly Subjects With Type 2 Diabetes

Completed

NCT00232583Not Applicable

Preservation of Beta-cell Function in Type 2 Diabetes Mellitus

Completed

NCT00279045Phase 3

Diabetes Study With Rosiglitazone Monotherapy Versus Metformin Or Glyburide/Glibenclamide

Completed

NCT01605773Phase 4

Effect of Repaglinide on Postprandial Lipemia in Type 2 Diabetes

Completed

NCT01698931Phase 4

Efficacy of Repaglinide in Subjects With Type 2 Diabetes

Completed

NCT00388986Phase 1

A Drug-Drug Interaction Study of GK Activator (2) and Glyburide in Patients With Type 2 Diabetes.

Completed

NCT02815787Phase 1

The Drug -Drug Interaction of SP2086 and Glyburide

Completed

NCT01947699Phase 4

Glycemic Profile in Women With Gestational Diabetes Treated With Glyburide

Withdrawn

NCT00313313Phase 3

A Study of Saxagliptin in Subjects With Type 2 Diabetes Who Have Inadequate Blood Sugar Control With Sulfonylureas

Completed

Drug Details

Intervention Type: DRUG
Total Trials: 41