Success Metrics

Clinical Success Rate
66.7%

Based on 4 completed trials

Completion Rate
67%(4/6)
Active Trials
47(65%)
Results Posted
25%(1 trials)
Terminated
2(3%)

Phase Distribution

Ph phase_1
23
32%
Ph early_phase_1
1
1%
Ph phase_2
39
54%
Ph phase_3
3
4%

Phase Distribution

24

Early Stage

39

Mid Stage

3

Late Stage

Phase Distribution66 total trials
Early Phase 1First-in-human
1(1.5%)
Phase 1Safety & dosage
23(34.8%)
Phase 2Efficacy & side effects
39(59.1%)
Phase 3Large-scale testing
3(4.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

57.1%

4 of 7 finished

Non-Completion Rate

42.9%

3 ended early

Currently Active

47

trials recruiting

Total Trials

72

all time

Status Distribution
Active(64)
Completed(4)
Terminated(3)
Other(1)

Detailed Status

Recruiting33
Not yet recruiting17
Active, not recruiting14
Completed4
Terminated2
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
72
Active
47
Success Rate
66.7%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (1.5%)
Phase 123 (34.8%)
Phase 239 (59.1%)
Phase 33 (4.5%)

Trials by Status

terminated23%
active_not_recruiting1419%
withdrawn11%
completed46%
not_yet_recruiting1724%
recruiting3346%
suspended11%

Recent Activity

Clinical Trials (72)

Showing 20 of 72 trialsScroll for more
NCT07003295Phase 2

Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

Recruiting
NCT03075696Phase 1

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

Active Not Recruiting
NCT07724457Phase 2

Testing the Addition of a New Anti-Cancer Drug, Glofitamab to Usual Chemotherapy for Burkitt and Double Hit Lymphoma

Not Yet Recruiting
NCT06252675Phase 2

Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma

Recruiting
NCT06634589Phase 1

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Recruiting
NCT06765317Phase 2

A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma

Recruiting
NCT05861050Phase 1

Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell Lymphoma

Recruiting
NCT07717177Phase 2

AI-Driven Treatment Strategy vs ZR2 in Older Treatment-naive Patients With LBCL

Not Yet Recruiting
NCT06806033Phase 2

A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Recruiting
NCT04970901Phase 1

A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)

Active Not Recruiting
NCT07711483Phase 2

GLORY: Glofit-GemOx With Liso-Cel For Lymphoma

Not Yet Recruiting
NCT07599423Phase 2

A Study of Glofitamab Plus GemOx Compared With Standard of Care in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Not Yet Recruiting
NCT07695896

Real-World Study of Bispecific Antibody in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Not Yet Recruiting
NCT06558604Phase 2

Phase II Study of Glofitamab With Venetoclax +/- Zanubrutinib in High-risk Mantle-cell Lymphoma

Recruiting
NCT07649304Phase 1

AMC 120, Glofitamab Plus Chemoimmunotherapy in Newly Diagnosed HIV-Associated Large B-Cell Lymphoma (The "Glofit-RCHOP Study")

Not Yet Recruiting
NCT07444710Phase 1

Testing the Addition of an Anti-Cancer Drug, Glofitamab, to the Usual Chemotherapy Treatment (Alternating R-CHOP/R-DHAP) for Previously Untreated Mantle Cell Lymphoma

Not Yet Recruiting
NCT04408638Phase 3

A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Active Not Recruiting
NCT03533283Phase 1

An Open-Label Phase lB/II Study of Glofitamab and Atezolizumab or Polatuzumab Vedotin in Adult Patients With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

Active Not Recruiting
NCT06922604Phase 1

Glofitamab With Obinutuzumab Pre-treatment for the Treatment of Central Nervous System Lymphoma

Suspended
NCT05533775Phase 1

A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
72