Success Metrics

Clinical Success Rate
66.7%

Based on 4 completed trials

Completion Rate
67%(4/6)
Active Trials
46(73%)
Results Posted
25%(1 trials)
Terminated
2(3%)

Phase Distribution

Ph phase_3
3
5%
Ph phase_2
32
51%
Ph early_phase_1
1
2%
Ph phase_1
22
35%

Phase Distribution

23

Early Stage

32

Mid Stage

3

Late Stage

Phase Distribution58 total trials
Early Phase 1First-in-human
1(1.7%)
Phase 1Safety & dosage
22(37.9%)
Phase 2Efficacy & side effects
32(55.2%)
Phase 3Large-scale testing
3(5.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

57.1%

4 of 7 finished

Non-Completion Rate

42.9%

3 ended early

Currently Active

46

trials recruiting

Total Trials

63

all time

Status Distribution
Active(56)
Completed(4)
Terminated(3)

Detailed Status

Recruiting34
Active, not recruiting12
Not yet recruiting10
Completed4
Terminated2
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
63
Active
46
Success Rate
66.7%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (1.7%)
Phase 122 (37.9%)
Phase 232 (55.2%)
Phase 33 (5.2%)

Trials by Status

recruiting3454%
not_yet_recruiting1016%
terminated23%
withdrawn12%
active_not_recruiting1219%
completed46%

Recent Activity

Clinical Trials (63)

Showing 20 of 63 trialsScroll for more
NCT05896163Phase 1

A Study to Learn About the Effects of Two Study Medicines (Maplirpacept [PF-07901801] And Glofitamab) When Given Together In People With Relapsed Or Refractory Diffuse Large B Cell Lymphoma.

Terminated
NCT06624085Phase 1

A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Recruiting
NCT05533775Phase 1

A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

Recruiting
NCT07200375

An Observational Study of Glofitamab in Chinese Adult Participants With 2L Diffuse Large B-Cell Lymphoma

Recruiting
NCT06084936Phase 3

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

Recruiting
NCT06765317Phase 2

A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma

Recruiting
NCT03075696Phase 1

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

Active Not Recruiting
NCT06806033Phase 2

A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Recruiting
NCT06050694Phase 2

Feasibility Trial of Glofitamab in a Response Adapted Approach Incorporating Interim FDG PET and ctDNA to Optimize Primary Therapy of DLBCL (GRAIL)

Recruiting
NCT06252675Phase 2

Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma

Recruiting
NCT07528352Phase 1

External Beam Radiotherapy Followed by Bispecific Antibody Therapy for Relapsed/Refractory DLBCL

Not Yet Recruiting
NCT07453095Phase 2

Study With Glofitamab in Patients With MCL and Inadequate Response or Relapse Following CAR T-cell Therapy

Not Yet Recruiting
NCT07257055Phase 2

Phase 2 Study of BTKi-Rituximab Induction Followed by Glofitamab Consolidation in High Risk Untreated MCL Patients - WINDOW-4 Study

Recruiting
NCT07003295Phase 2

Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

Recruiting
NCT06634589Phase 1

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Recruiting
NCT07444710Phase 1

Testing the Addition of an Anti-Cancer Drug, Glofitamab, to the Usual Chemotherapy Treatment (Alternating R-CHOP/R-DHAP) for Previously Untreated Mantle Cell Lymphoma

Not Yet Recruiting
NCT05798156Phase 2

Rituximab in Combination With Glofitamab and Polatuzumab Vedotin in Patients With Previously Untreated Aggressive B-cell Lymphoma Ineligible for R-CHOP

Active Not Recruiting
NCT07502872Phase 2

TPG: Tafasitamab, Polatuzumab Vedotin, and Glofitamab as First-line Therapy for Diffuse Large B-cell Lymphoma and High-grade B-cell Lymphoma

Not Yet Recruiting
NCT06192888Phase 1

A Study of Glofitamab and Lenalidomide in People With Mantle Cell Lymphoma

Active Not Recruiting
NCT06481826

Glofitamab in Chinese Patients With R/R DLBCL

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
63