Success Metrics

Clinical Success Rate
100.0%

Based on 13 completed trials

Completion Rate
100%(13/13)
Active Trials
3(15%)
Results Posted
77%(10 trials)

Phase Distribution

Ph not_applicable
1
5%
Ph phase_1
1
5%
Ph phase_2
1
5%
Ph phase_3
10
50%
Ph phase_4
3
15%
Ph early_phase_1
1
5%

Phase Distribution

2

Early Stage

1

Mid Stage

13

Late Stage

Phase Distribution17 total trials
Early Phase 1First-in-human
1(5.9%)
Phase 1Safety & dosage
1(5.9%)
Phase 2Efficacy & side effects
1(5.9%)
Phase 3Large-scale testing
10(58.8%)
Phase 4Post-market surveillance
3(17.6%)
N/ANon-phased studies
1(5.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

92.9%

13 of 14 finished

Non-Completion Rate

7.1%

1 ended early

Currently Active

3

trials recruiting

Total Trials

20

all time

Status Distribution
Active(3)
Completed(13)
Terminated(1)
Other(3)

Detailed Status

Completed13
unknown3
Recruiting3
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
20
Active
3
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (5.9%)
Phase 11 (5.9%)
Phase 21 (5.9%)
Phase 310 (58.8%)
Phase 43 (17.6%)
N/A1 (5.9%)

Trials by Status

unknown315%
recruiting315%
withdrawn15%
completed1365%

Recent Activity

Clinical Trials (20)

Showing 20 of 20 trials
NCT07040319Phase 1

Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIV

Recruiting
NCT06367465

Feasibility and Acceptability of HCV Treatment in Pregnancy

Recruiting
NCT05637879Phase 2

Glecaprevir/Pibrentasvir for Post-traumatic Stress Disorder

Recruiting
NCT04682509Early Phase 1

A Single-center Pilot Study Evaluating a Preemptive Short Course of Glecaprevir/Pibrentasvir in Hepatitis C Positive to Negative Kidney Transplantation

Completed
NCT04575896Phase 4

Kidney Transplants in Hepatitis C Negative Recipients With Hepatitis C Viremic Donors

Completed
NCT03492112Not Applicable

A TEst and Treat Intervention aMong Current People Who Inject Drugs With HCV Attending Needle and Syringe PrOgrams

Completed
NCT02634008Phase 3

Treatment of Recently Acquired Hepatitis C With the 3D Regimen or G/P

Completed
NCT02939989Phase 3

Efficacy and Safety of Glecaprevir (ABT-493)/Pibrentasvir (ABT 530) (GLE/PIB) in Combination With Sofosbuvir and Ribavirin in Participants With Hepatitis C Virus Who Did Not Respond to Treatment in a Previous AbbVie Clinical Study

Completed
NCT03776760

Strategies for Hepatitis C Testing and Treatment in Aboriginal Communities That Lead to Elimination

Unknown
NCT02966795Phase 3

A Study of of Glecaprevir/Pibrentasvir in Adults With Chronic Hepatitis C Virus (HCV) Genotype 5 or 6 Infection

Completed
NCT02692703Phase 3

A Study to Evaluate the Safety and Efficacy of ABT-493/ABT-530 in Adult Post-Liver or Post-Renal Transplant Recipients With Chronic Hepatitis C Virus (MAGELLAN-2)

Completed
NCT04235049Phase 4

Elimination of HCV Through Linkage and In Prison Treatment of Incarcerated Populations (ECLIPSE)

Withdrawn
NCT03089944Phase 3

A Study of Glecaprevir (GLE)/Pibrentasvir (PIB) in Treatment-Naive Adults With Chronic Hepatitis C Virus (HCV) Genotype 1-6 Infection and Compensated Cirrhosis

Completed
NCT03219216Phase 3

A Study to Evaluate the Efficacy and Safety of Glecaprevir (GLE)/Pibrentasvir (PIB) in Treatment-Naive Adults in Brazil With Chronic Hepatitis C Virus (HCV) Genotype 1 - 6 Infection

Completed
NCT03222583Phase 3

A Study to Evaluate the Efficacy and Safety of Glecaprevir/Pibrentasvir (ABT-493/ABT-530) in Treatment-Naive and Treatment-Experienced, Non-Cirrhotic Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With or Without Human Immunodeficiency Virus Co-Infection

Completed
NCT03235349Phase 3

Efficacy and Safety of Glecaprevir/Pibrentasvir (ABT-493/ABT-530) in Treatment-Naive and Treatment-Experienced Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With Compensated Cirrhosis and With or Without Human Immunodeficiency Virus Co-Infection

Completed
NCT03212521Phase 3

Efficacy and Safety of 8-weeks of Glecaprevir/Pibrentasvir in Treatment-Naïve Adults With HCV Genotype 1-6 and Aspartate Aminotransferase to Platelet Ratio Index (APRI) ≤1

Completed
NCT03941821

Glecaprevir/Pibrentasvir Real-world Study in China

Unknown
NCT03069365Phase 3

A Study to Evaluate the Efficacy and Safety of Glecaprevir/Pibrentasvir in Adults With Chronic Hepatitis C Virus Genotype 1 - 6 Infection and Renal Impairment

Completed
NCT03364725Phase 4

Toward Elimination of Hepatitis C Virus (HCV): A Pilot Study

Unknown

All 20 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
20