Success Metrics

Clinical Success Rate
78.9%

Based on 15 completed trials

Completion Rate
79%(15/19)
Active Trials
25(47%)
Results Posted
87%(13 trials)
Terminated
4(8%)

Phase Distribution

Ph phase_3
7
13%
Ph not_applicable
2
4%
Ph phase_1
28
53%
Ph phase_2
11
21%

Phase Distribution

28

Early Stage

11

Mid Stage

7

Late Stage

Phase Distribution48 total trials
Phase 1Safety & dosage
28(58.3%)
Phase 2Efficacy & side effects
11(22.9%)
Phase 3Large-scale testing
7(14.6%)
N/ANon-phased studies
2(4.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

75.0%

15 of 20 finished

Non-Completion Rate

25.0%

5 ended early

Currently Active

25

trials recruiting

Total Trials

53

all time

Status Distribution
Active(28)
Completed(15)
Terminated(5)
Other(5)

Detailed Status

Recruiting20
Completed15
Active, not recruiting5
Terminated4
unknown4
Not yet recruiting3

Development Timeline

Analytics

Development Status

Total Trials
53
Active
25
Success Rate
78.9%
Most Advanced
Phase 3

Trials by Phase

Phase 128 (58.3%)
Phase 211 (22.9%)
Phase 37 (14.6%)
N/A2 (4.2%)

Trials by Status

suspended12%
completed1528%
not_yet_recruiting36%
terminated48%
unknown48%
withdrawn12%
active_not_recruiting59%
recruiting2038%

Recent Activity

Clinical Trials (53)

Showing 20 of 53 trialsScroll for more
NCT06317649Phase 2

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT03182244Phase 3

A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase 3 (FLT3) Mutation

Active Not Recruiting
NCT07140016Phase 1

A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)

Recruiting
NCT07548710Phase 2

Study of SA+X in the Treatment of Newly Diagnosed AML

Recruiting
NCT05955261Phase 2

A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients With Acute Myeloid Leukemia

Suspended
NCT04140487Phase 1

Azacitidine, Venetoclax, and Gilteritinib in Treating Patients With Recurrent/Refractory FLT3-Mutated Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or High-Risk Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Recruiting
NCT07032727Phase 2

Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations

Recruiting
NCT06001788Phase 1

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Recruiting
NCT05756777Phase 1

A Study of Gilteritinib in Combination With Ivosidenib or Enasidenib in People With Acute Myeloid Leukemia (AML)

Recruiting
NCT04988555Phase 1

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

Recruiting
NCT07463651Phase 3

MRD-guided Maintenance Post-HCT: Gilteritini vs Sorafenib

Recruiting
NCT06222580Phase 1

SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

Recruiting
NCT05520567Phase 1

A Study of Gilteritinib, Venetoclax and Azacitidine as a Combined Treatment for People Newly Diagnosed With Acute Myeloid Leukemia

Active Not Recruiting
NCT07425808Phase 2

FLT3-ITD Targeted Therapy in Fit AML Patients

Not Yet Recruiting
NCT05010122Phase 1

ASTX727, Venetoclax, and Gilteritinib for the Treatment of Newly Diagnosed, Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Recruiting
NCT05010772Phase 1

Decitabine Alone or in Combination With Venetoclax, Gilteritinib, Enasidenib, or Ivosidenib as Maintenance Therapy for the Treatment of Acute Myeloid Leukemia in Remission

Recruiting
NCT04240002Phase 1

A Study of Gilteritinib (ASP2215) Combined With Chemotherapy in Children, Adolescents and Young Adults With FMS-like Tyrosine Kinase 3 (FLT3)/Internal Tandem Duplication (ITD) Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

Terminated
NCT05024552Phase 1

Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated AML

Recruiting
NCT02421939Phase 3

A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation

Completed

Drug Details

Intervention Type
DRUG
Total Trials
53