Success Metrics

Clinical Success Rate
80.0%

Based on 16 completed trials

Completion Rate
80%(16/20)
Active Trials
24(45%)
Results Posted
81%(13 trials)
Terminated
4(8%)

Phase Distribution

Ph phase_3
7
13%
Ph phase_2
11
21%
Ph not_applicable
2
4%
Ph phase_1
28
53%

Phase Distribution

28

Early Stage

11

Mid Stage

7

Late Stage

Phase Distribution48 total trials
Phase 1Safety & dosage
28(58.3%)
Phase 2Efficacy & side effects
11(22.9%)
Phase 3Large-scale testing
7(14.6%)
N/ANon-phased studies
2(4.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

76.2%

16 of 21 finished

Non-Completion Rate

23.8%

5 ended early

Currently Active

24

trials recruiting

Total Trials

53

all time

Status Distribution
Active(27)
Completed(16)
Terminated(5)
Other(5)

Detailed Status

Recruiting19
Completed16
Active, not recruiting5
unknown4
Terminated4
Not yet recruiting3

Development Timeline

Analytics

Development Status

Total Trials
53
Active
24
Success Rate
80.0%
Most Advanced
Phase 3

Trials by Phase

Phase 128 (58.3%)
Phase 211 (22.9%)
Phase 37 (14.6%)
N/A2 (4.2%)

Trials by Status

active_not_recruiting59%
recruiting1936%
unknown48%
completed1630%
not_yet_recruiting36%
terminated48%
withdrawn12%
suspended12%

Recent Activity

Clinical Trials (53)

Showing 20 of 53 trialsScroll for more
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT06317649Phase 2

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Recruiting
NCT07548710Phase 2

Study of SA+X in the Treatment of Newly Diagnosed AML

Recruiting
NCT05955261Phase 2

A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients With Acute Myeloid Leukemia

Suspended
NCT03836209Phase 2

Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemia

Completed
NCT05010122Phase 1

ASTX727, Venetoclax, and Gilteritinib for the Treatment of Newly Diagnosed, Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Recruiting
NCT03182244Phase 3

A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase 3 (FLT3) Mutation

Active Not Recruiting
NCT05010772Phase 1

Decitabine Alone or in Combination With Venetoclax, Gilteritinib, Enasidenib, or Ivosidenib as Maintenance Therapy for the Treatment of Acute Myeloid Leukemia in Remission

Recruiting
NCT02752035Phase 3

A Study of ASP2215 (Gilteritinib) by Itself, ASP2215 Combined With Azacitidine or Azacitidine by Itself to Treat Adult Patients Who Have Recently Been Diagnosed With Acute Myeloid Leukemia With a FLT3 Gene Mutation and Who Cannot Receive Standard Chemotherapy

Completed
NCT06225427Phase 1

Gilteritinib for the Treatment of ALK NSCLC

Recruiting
NCT07140016Phase 1

A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)

Recruiting
NCT06992934Not Applicable

Immunological Impact of a Post Cell Therapy Treatment With FLT3 Inhibitors

Not Yet Recruiting
NCT05756777Phase 1

A Study of Gilteritinib in Combination With Ivosidenib or Enasidenib in People With Acute Myeloid Leukemia (AML)

Recruiting
NCT06235801Phase 1

A Phase I/II Study of Gilteritinib and Momelotinib for Patients With Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia

Active Not Recruiting
NCT02115295Phase 2

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

Recruiting
NCT06222580Phase 1

SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

Recruiting
NCT06561880Phase 1

The Efficacy of Triple Regimen in Newly Diagnosed AML Patients With FLT3 Mutation

Recruiting
NCT04140487Phase 1

Azacitidine, Venetoclax, and Gilteritinib in Treating Patients With Recurrent/Refractory FLT3-Mutated Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or High-Risk Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Recruiting
NCT07032727Phase 2

Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations

Recruiting
NCT06001788Phase 1

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
53