Success Metrics

Clinical Success Rate
75.7%

Based on 676 completed trials

Completion Rate
76%(676/893)
Active Trials
322(22%)
Results Posted
65%(438 trials)
Terminated
217(15%)

Phase Distribution

Ph not_applicable
19
1%
Ph phase_3
255
17%
Ph phase_4
7
0%
Ph phase_1
449
31%
Ph phase_2
714
49%
Ph early_phase_1
13
1%

Phase Distribution

462

Early Stage

714

Mid Stage

262

Late Stage

Phase Distribution1457 total trials
Early Phase 1First-in-human
13(0.9%)
Phase 1Safety & dosage
449(30.8%)
Phase 2Efficacy & side effects
714(49.0%)
Phase 3Large-scale testing
255(17.5%)
Phase 4Post-market surveillance
7(0.5%)
N/ANon-phased studies
19(1.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.5%

676 of 946 finished

Non-Completion Rate

28.5%

270 ended early

Currently Active

322

trials recruiting

Total Trials

1,471

all time

Status Distribution
Active(369)
Completed(676)
Terminated(270)
Other(156)

Detailed Status

Completed676
Terminated217
Recruiting200
unknown152
Active, not recruiting122
Withdrawn53

Development Timeline

Analytics

Development Status

Total Trials
1471
Active
322
Success Rate
75.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 113 (0.9%)
Phase 1449 (30.8%)
Phase 2714 (49.0%)
Phase 3255 (17.5%)
Phase 47 (0.5%)
N/A19 (1.3%)

Trials by Status

suspended40%
terminated21715%
withdrawn534%
active_not_recruiting1228%
not_yet_recruiting453%
completed67646%
enrolling_by_invitation20%
unknown15210%
recruiting20014%

Recent Activity

Clinical Trials (1,471)

Showing 20 of 1,471 trialsScroll for more
NCT04960618Phase 2

Pembrolizumab in Combination With Gemcitabine in People With Advanced Mycosis Fungoides or Sézary Syndrome

Active Not Recruiting
NCT06467357Phase 3

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

Recruiting
NCT06843447Phase 1

A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)

Recruiting
NCT06064097Phase 2

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

Recruiting
NCT06694454Phase 1

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT03703375Phase 3

Efficacy and Safety of Oral Azacitidine (CC-486) Compared to Investigator's Choice Therapy in Patients With Relapsed or Refractory Angioimmunoblastic T Cell Lymphoma

Completed
NCT06841354Phase 3

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Recruiting
NCT07575191Phase 1

Safety and Performance of a Novel Infusion Catheter System for Peri/Intratumoral Gemcitabine Delivery in Patients With Pancreatic Cancer

Recruiting
NCT05548296Phase 2

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

Recruiting
NCT05630183Phase 2

A Study of Botensilimab in Participants With Metastatic Pancreatic Cancer

Completed
NCT06029270Phase 2

Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer

Recruiting
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting
NCT01352962Phase 1

Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors

Completed
NCT03321643Phase 1

Testing the Addition of an Immunotherapy Agent, Atezolizumab, When Given With the Usual Chemo-Immunotherapy Drug Combination (Rituximab Plus Gemcitabine and Oxaliplatin) for Relapsed/Refractory (That Has Come Back or Not Responded to Treatment) Transformed Diffuse Large B-Cell Lymphoma

Active Not Recruiting
NCT06524544Phase 3

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Recruiting
NCT06960577Phase 3

Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2)

Recruiting
NCT06926868Phase 2

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Recruiting
NCT02481635Phase 1

A Study of Gemcitabine/Nab-paclitaxel and Radiation Therapy Followed by Surgery in Patients With Advanced Pancreatic Cancer

Active Not Recruiting
NCT07640048

Adjuvant Therapy for High-Risk Intrahepatic Cholangiocarcinoma: A Real-World Study

Recruiting
NCT05827055Phase 2

Proglumide and Chemotherapy for Metastatic Pancreatic Cancer

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,471