Success Metrics

Clinical Success Rate
75.4%

Based on 677 completed trials

Completion Rate
75%(677/898)
Active Trials
328(22%)
Results Posted
66%(446 trials)
Terminated
221(15%)

Phase Distribution

Ph early_phase_1
13
1%
Ph not_applicable
19
1%
Ph phase_1
449
30%
Ph phase_3
260
18%
Ph phase_4
7
0%
Ph phase_2
720
49%

Phase Distribution

462

Early Stage

720

Mid Stage

267

Late Stage

Phase Distribution1468 total trials
Early Phase 1First-in-human
13(0.9%)
Phase 1Safety & dosage
449(30.6%)
Phase 2Efficacy & side effects
720(49.0%)
Phase 3Large-scale testing
260(17.7%)
Phase 4Post-market surveillance
7(0.5%)
N/ANon-phased studies
19(1.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.1%

677 of 952 finished

Non-Completion Rate

28.9%

275 ended early

Currently Active

328

trials recruiting

Total Trials

1,482

all time

Status Distribution
Active(375)
Completed(677)
Terminated(275)
Other(155)

Detailed Status

Completed677
Terminated221
Recruiting204
unknown151
Active, not recruiting124
Withdrawn54

Development Timeline

Analytics

Development Status

Total Trials
1482
Active
328
Success Rate
75.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 113 (0.9%)
Phase 1449 (30.6%)
Phase 2720 (49.0%)
Phase 3260 (17.7%)
Phase 47 (0.5%)
N/A19 (1.3%)

Trials by Status

recruiting20414%
withdrawn544%
enrolling_by_invitation20%
terminated22115%
completed67746%
not_yet_recruiting453%
suspended40%
unknown15110%
active_not_recruiting1248%

Recent Activity

Clinical Trials (1,482)

Showing 20 of 1,482 trialsScroll for more
NCT06624085Phase 1

A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Active Not Recruiting
NCT06459180Phase 3

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

Active Not Recruiting
NCT05139017Phase 2

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

Recruiting
NCT06694454Phase 1

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT06841354Phase 3

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Recruiting
NCT01352962Phase 1

Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors

Completed
NCT05999994Phase 2

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

Recruiting
NCT03618550Phase 2

Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin Lymphoma

Recruiting
NCT07748611Phase 2

SMAD4 Tailored Neoadjuvant Therapy for the Treatment of Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma, SMART-PANC Trial

Not Yet Recruiting
NCT02595892Phase 2

Gemcitabine Hydrochloride Alone or With M6620 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Active Not Recruiting
NCT07213804Phase 3

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

Recruiting
NCT06050252Phase 2

Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery

Recruiting
NCT06545955Phase 3

A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer

Recruiting
NCT07566156Phase 3

Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

Recruiting
NCT04999761Phase 1

AB122 Platform Study

Recruiting
NCT05171647Phase 3

A Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab Vedotin Compared to Rituximab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Active Not Recruiting
NCT06632327Phase 3

Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

Recruiting
NCT06064097Phase 2

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

Recruiting
NCT07564141Phase 3

Study to Assess the Efficacy and Safety of Rina-S With or Without Bevacizumab Compared to Investigator's Choice of Platinum-based Chemotherapy With or Without Bevacizumab as Second-line Treatment in Participants With Recurrent Platinum-sensitive Ovarian Cancer

Recruiting
NCT07000084Phase 3

Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,482