Success Metrics

Clinical Success Rate
75.4%

Based on 678 completed trials

Completion Rate
75%(678/899)
Active Trials
327(22%)
Results Posted
66%(447 trials)
Terminated
221(15%)

Phase Distribution

Ph not_applicable
19
1%
Ph phase_1
449
30%
Ph phase_3
260
18%
Ph phase_2
720
49%
Ph phase_4
7
0%
Ph early_phase_1
13
1%

Phase Distribution

462

Early Stage

720

Mid Stage

267

Late Stage

Phase Distribution1468 total trials
Early Phase 1First-in-human
13(0.9%)
Phase 1Safety & dosage
449(30.6%)
Phase 2Efficacy & side effects
720(49.0%)
Phase 3Large-scale testing
260(17.7%)
Phase 4Post-market surveillance
7(0.5%)
N/ANon-phased studies
19(1.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.1%

678 of 953 finished

Non-Completion Rate

28.9%

275 ended early

Currently Active

327

trials recruiting

Total Trials

1,482

all time

Status Distribution
Active(374)
Completed(678)
Terminated(275)
Other(155)

Detailed Status

Completed678
Terminated221
Recruiting204
unknown151
Active, not recruiting123
Withdrawn54

Development Timeline

Analytics

Development Status

Total Trials
1482
Active
327
Success Rate
75.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 113 (0.9%)
Phase 1449 (30.6%)
Phase 2720 (49.0%)
Phase 3260 (17.7%)
Phase 47 (0.5%)
N/A19 (1.3%)

Trials by Status

active_not_recruiting1238%
withdrawn544%
completed67846%
terminated22115%
unknown15110%
enrolling_by_invitation20%
recruiting20414%
suspended40%
not_yet_recruiting453%

Recent Activity

Clinical Trials (1,482)

Showing 20 of 1,482 trialsScroll for more
NCT04179162Phase 1

Bacillus Calmette-Guérin (BCG) and Gemcitabine in People With High-Grade Non-Muscle Invasive Bladder Cancer That Came Back After BCG Treatment

Active Not Recruiting
NCT02436707Phase 2

Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell Lymphoma

Active Not Recruiting
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting
NCT04594772Phase 2

Adaptive Approach to Neoadjuvant Therapy to Maximize Resection Rates for Pancreatic Adenocarcinoma

Active Not Recruiting
NCT06524544Phase 3

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Recruiting
NCT07420439Phase 2

Treatment in Patients With Advanced Non-Small Cell Lung Carcinoma and Interstitial Lung Disease

Not Yet Recruiting
NCT06694454Phase 1

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT05825066Phase 2

Neoadjuvant Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

Recruiting
NCT03587662Phase 2

Ixazomib, Gemcitabine, and Doxorubicin in Treating Patients With Locally Advanced or Metastatic Kidney Cancer

Completed
NCT03656536Phase 3

A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma

Terminated
NCT07743164Phase 3

A Clinical Trial of Raludotatug Deruxtecan (R-DXd) With or Without Bevacizumab in Participants With Ovarian Cancer Who Have Progressed During Treatment With PARP-inhibitors Treatment on First Line Maintenance (MK-5909-008/ENGOT-ov107/GOG-3142 / REJOICE-Ovarian05)

Not Yet Recruiting
NCT04892953Phase 2

Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy

Recruiting
NCT06926868Phase 2

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Recruiting
NCT06029270Phase 2

Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer

Recruiting
NCT01352962Phase 1

Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors

Completed
NCT06576115Phase 2

Gemcitabine, Nab-paclitaxel Plus the TheraBionic P1 (an Amplitude-Modulated Radiofrequency Electromagnetic Fields) Device to Treat Metastatic Pancreatic Cancer

Recruiting
NCT06623422Phase 3

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

Recruiting
NCT06624085Phase 1

A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Active Not Recruiting
NCT06841354Phase 3

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Recruiting
NCT05999994Phase 2

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,482