Success Metrics

Clinical Success Rate
75.9%

Based on 669 completed trials

Completion Rate
76%(669/882)
Active Trials
324(22%)
Results Posted
65%(433 trials)
Terminated
213(15%)

Phase Distribution

Ph phase_2
711
49%
Ph phase_4
7
0%
Ph phase_1
445
31%
Ph phase_3
250
17%
Ph not_applicable
19
1%
Ph early_phase_1
13
1%

Phase Distribution

458

Early Stage

711

Mid Stage

257

Late Stage

Phase Distribution1445 total trials
Early Phase 1First-in-human
13(0.9%)
Phase 1Safety & dosage
445(30.8%)
Phase 2Efficacy & side effects
711(49.2%)
Phase 3Large-scale testing
250(17.3%)
Phase 4Post-market surveillance
7(0.5%)
N/ANon-phased studies
19(1.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.6%

669 of 934 finished

Non-Completion Rate

28.4%

265 ended early

Currently Active

324

trials recruiting

Total Trials

1,458

all time

Status Distribution
Active(368)
Completed(669)
Terminated(265)
Other(156)

Detailed Status

Completed669
Terminated213
Recruiting199
unknown153
Active, not recruiting125
Withdrawn52

Development Timeline

Analytics

Development Status

Total Trials
1458
Active
324
Success Rate
75.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 113 (0.9%)
Phase 1445 (30.8%)
Phase 2711 (49.2%)
Phase 3250 (17.3%)
Phase 47 (0.5%)
N/A19 (1.3%)

Trials by Status

completed66946%
terminated21315%
recruiting19914%
active_not_recruiting1259%
not_yet_recruiting443%
suspended30%
unknown15310%
withdrawn524%

Recent Activity

Clinical Trials (1,458)

Showing 20 of 1,458 trialsScroll for more
NCT05967182Phase 2

A Single-Arm Study of Pembrolizumab With Gemcitabine and Cisplatin as Perioperative Therapy for Potentially Resectable Intrahepatic Cholangiocarcinoma

Recruiting
NCT05498220Phase 2

Polatuzumab Vedotin With R-GDP in Relapsed/Refractory Diffuse Large B-cell Lymphoma

Terminated
NCT06467357Phase 3

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

Recruiting
NCT04940286Phase 2

Gemcitabine, Nab-paclitaxel, Durvalumab, and Oleclumab Before Surgery for the Treatment of in Resectable/Borderline Resectable Primary Pancreatic Cancer

Active Not Recruiting
NCT03618550Phase 2

Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin Lymphoma

Recruiting
NCT07532902Phase 1

A Study of BMS-986504 With Standard-of-Care Therapy for People With Solid Tumor Cancer

Recruiting
NCT07283705Phase 2

A Phase II Study Evaluating BMS-986504 in MTAP-deleted Pancreatic Cancer

Recruiting
NCT00479128Phase 1

Bortezomib With Gemcitabine/Doxorubicin in Patients With Urothelial Cancer and Other Solid Tumors

Active Not Recruiting
NCT05497778Phase 1

A Phase 1b Study of Gemcitabine and Nab-paclitaxel in Combination With IM156 in Patients With Advanced Pancreatic Cancer.

Active Not Recruiting
NCT06694454Phase 1

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Not Yet Recruiting
NCT07444541Phase 1

ANO31905 in Combination With Chemotherapy for CLDN18.2-Positive Locally Advanced Unresectable or Metastatic Pancreatic Cancer

Not Yet Recruiting
NCT04924062Phase 3

Pembrolizumab (MK-3475) Plus Gemcitabine/Cisplatin Versus Placebo Plus Gemcitabine/Cisplatin for First-Line Advanced and/or Unresectable Biliary Tract Carcinoma (BTC) (MK-3475-966/KEYNOTE-966)-China Extension Study

Completed
NCT03317158Phase 1

Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder

Recruiting
NCT04481204Phase 2

New and Emerging Therapies for the Treatment of Resectable, Borderline Resectable, or Locally Advanced Pancreatic Cancer, PIONEER-Panc Study

Active Not Recruiting
NCT07106762Phase 2

Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy

Recruiting
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting
NCT05616624Phase 1

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

Active Not Recruiting
NCT03661320Phase 3

A Study to Compare Chemotherapy Alone Versus Chemotherapy Plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Therapy After Surgery With Nivolumab or Nivolumab and BMS-986205 in Participants With Muscle Invasive Bladder Cancer

Active Not Recruiting
NCT06524544Phase 3

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Recruiting
NCT01352962Phase 1

Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors

Completed

Drug Details

Intervention Type
DRUG
Total Trials
1,458