Success Metrics

Clinical Success Rate
87.2%

Based on 136 completed trials

Completion Rate
87%(136/156)
Active Trials
9(4%)
Results Posted
32%(44 trials)
Terminated
20(9%)

Phase Distribution

Ph not_applicable
7
3%
Ph phase_2
119
56%
Ph phase_4
6
3%
Ph phase_3
36
17%
Ph phase_1
43
20%

Phase Distribution

43

Early Stage

119

Mid Stage

42

Late Stage

Phase Distribution211 total trials
Phase 1Safety & dosage
43(20.4%)
Phase 2Efficacy & side effects
119(56.4%)
Phase 3Large-scale testing
36(17.1%)
Phase 4Post-market surveillance
6(2.8%)
N/ANon-phased studies
7(3.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

85.5%

136 of 159 finished

Non-Completion Rate

14.5%

23 ended early

Currently Active

9

trials recruiting

Total Trials

214

all time

Status Distribution
Active(9)
Completed(136)
Terminated(23)
Other(46)

Detailed Status

Completed136
unknown45
Terminated20
Active, not recruiting8
Withdrawn3
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
214
Active
9
Success Rate
87.2%
Most Advanced
Phase 4

Trials by Phase

Phase 143 (20.4%)
Phase 2119 (56.4%)
Phase 336 (17.1%)
Phase 46 (2.8%)
N/A7 (3.3%)

Trials by Status

active_not_recruiting84%
recruiting10%
terminated209%
suspended10%
unknown4521%
withdrawn31%
completed13664%

Recent Activity

Clinical Trials (214)

Showing 20 of 214 trialsScroll for more
NCT03122717Phase 1

Osimertinib and Gefitinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer

Active Not Recruiting
NCT03040973Phase 2

Study to Allow Patients Previously Participating in a Novartis Sponsored Trial to Continue Receiving Capmatinib Treatment as Single Agent or in Combination With Other Treatments or the Combination Treatment Alone

Active Not Recruiting
NCT07477457Phase 2

A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma

Recruiting
NCT03333343Phase 1

Study of EGF816 in Combination With Selected Targeted Agents in EGFR-mutant NSCLC

Active Not Recruiting
NCT02411448Phase 3

A Study of Ramucirumab (LY3009806) in Combination With Erlotinib in Previously Untreated Participants With EGFR Mutation-Positive Metastatic NSCLC (RELAY)

Active Not Recruiting
NCT02856893Phase 2

Osimertinib Treatment on EGFR T790M Plasma Positive NSCLC Patients (APPLE)

Active Not Recruiting
NCT03653546Phase 2

First Line Treatment in EGFR Mutation Positive Advanced NSCLC Patients With Central Nervous System (CNS) Metastases

Completed
NCT03292133Phase 2

A Study of EGF816 and Gefitinib in TKI-naïve EGFR-mutant Non-Small Cell Lung Cancer

Terminated
NCT05834348

A Study to Learn About the Effectiveness of Cancer Medicines in Patients With Metastatic Non-small Cell Lung Cancer in Norway.

Completed
NCT03944772Phase 2

Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)

Active Not Recruiting
NCT02588261Phase 3

A Study of ASP8273 vs. Erlotinib or Gefitinib in First-line Treatment of Patients With Stage IIIB/IV Non-small Cell Lung Cancer Tumors With EGFR Activating Mutations

Terminated
NCT03866499Phase 3

A Study of BPI-7711 Capsule in Non-small Cell Lung Cancer Patients

Active Not Recruiting
NCT01513174Phase 1

Study With Gefitinib in Combination With Olaparib (AZD2281) Versus Gefitinib Alone

Completed
NCT04143607Phase 3

ASK120067 Versus Gefitinib as First-line Treatment for EGFRm Locally Advanced or Metastatic NSCLC

Active Not Recruiting
NCT00198380Phase 2

Treatment of Lung Adenocarcinoma With Bronchioloalveolar Feature

Completed
NCT01485809Phase 2

Efficacy and Safety Study of Gefitinib in Squamous NSCLC Patients Who Failed First-Line Chemotherapy

Completed
NCT01774721Phase 3

ARCHER1050: A Study of Dacomitinib vs. Gefitinib in 1st-Line Treatment Of Advanced NSCLC.

Completed
NCT00352079Phase 3

BCG With or Without Gefitinib in Treating Patients With High-Risk Bladder Cancer

Terminated
NCT01833572Phase 2

Preoperative Gefitinib for EGFR Mutant II-IIIa NSCLC (ECTOP-1001)

Completed
NCT03599518Phase 1

DS-1205c With Gefitinib for Metastatic or Unresectable Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
214