Success Metrics

Clinical Success Rate
64.7%

Based on 11 completed trials

Completion Rate
65%(11/17)
Active Trials
1(5%)
Results Posted
82%(9 trials)
Terminated
6(32%)

Phase Distribution

Ph not_applicable
1
5%
Ph phase_1
11
58%
Ph phase_3
1
5%
Ph phase_2
6
32%

Phase Distribution

11

Early Stage

6

Mid Stage

1

Late Stage

Phase Distribution19 total trials
Phase 1Safety & dosage
11(57.9%)
Phase 2Efficacy & side effects
6(31.6%)
Phase 3Large-scale testing
1(5.3%)
N/ANon-phased studies
1(5.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

61.1%

11 of 18 finished

Non-Completion Rate

38.9%

7 ended early

Currently Active

1

trials recruiting

Total Trials

19

all time

Status Distribution
Active(1)
Completed(11)
Terminated(7)

Detailed Status

Completed11
Terminated6
Recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
19
Active
1
Success Rate
64.7%
Most Advanced
Phase 3

Trials by Phase

Phase 111 (57.9%)
Phase 26 (31.6%)
Phase 31 (5.3%)
N/A1 (5.3%)

Trials by Status

recruiting15%
terminated632%
withdrawn15%
completed1158%

Recent Activity

Clinical Trials (19)

Showing 19 of 19 trials
NCT01042379Phase 2

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

Recruiting
NCT01560416Phase 2

Fulvestrant With or Without Ganetespib in HR+ Breast Cancer

Completed
NCT03783949Phase 2

European Trial on Enhanced DNA Repair Inhibition in Ovarian Cancer

Completed
NCT01962948Phase 1

Paclitaxel and Ganetespib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Terminated
NCT01590160Phase 1

Ganetespib With Platinum, in Patients With Malignant Pleural Mesothelioma

Completed
NCT02012192Phase 1

GANNET53: Ganetespib in Metastatic, p53-mutant, Platinum-resistant Ovarian Cancer

Terminated
NCT02389751Phase 1

Ganetespib in Combination With Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Stage II-III Esophageal Cancer

Completed
NCT02008877Phase 1

SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors)

Completed
NCT02060253Phase 1

Ganetespib, Paclitaxel, Trastuzumab and Pertuzumab for Metastatic Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer

Completed
NCT02261805Phase 1

A Phase I/II Study of Ganetespib in Combination With Doxorubicin

Terminated
NCT02192541Phase 1

Ganetespib and Ziv-Aflibercept in Refractory Gastrointestinal Carcinomas, Non-Squamous Non-Small Cell Lung Carcinomas, Urothelial Carcinomas, and Sarcomas

Terminated
NCT02334319Phase 1

Ganetespib Window of Opportunity Study in Head and Neck Cancers

Terminated
NCT01798485Phase 3

A Phase 3 Study of Ganetespib in Combination With Docetaxel Versus Docetaxel Alone in Patients With Advanced NSCLC

Terminated
NCT02637375Not Applicable

A Pilot Preoperative Trial of Ganetespib With Paclitaxel for Triple-Negative Breast Cancer

Withdrawn
NCT01039519Phase 2

A Study Evaluating STA-9090 in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor (GIST)

Completed
NCT01677455Phase 2

An Open-Label Multicenter Phase 2 Window of Opportunity Study Evaluating Ganetespib in Women With Breast Cancer

Completed
NCT01485835Phase 1

A Phase I Study of Ganetespib +/- Bortezomib in Patients With Relapsed and/or Refractory Multiple Myeloma

Completed
NCT01562015Phase 2

A Study of Ganetespib in Subjects With ALK-Positive Non-Small-Cell Lung Cancer (NSCLC)

Completed
NCT01236144Phase 1

A Trial to Establish the Feasibility of Combining Either the Tyrosine Kinase Inhibitor AC220,CXCR4 Inhibitor Plerixafor or HSP90 Inhibitor Ganetespib With Chemotherapy in Older Patients With Acute Myeloid Leukaemia and High Risk Myelodysplastic Syndrome.

Completed

All 19 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
19