Success Metrics

Clinical Success Rate
76.5%

Based on 26 completed trials

Completion Rate
76%(26/34)
Active Trials
4(10%)
Results Posted
58%(15 trials)
Terminated
8(20%)

Phase Distribution

Ph phase_1
19
46%
Ph phase_2
13
32%
Ph phase_3
5
12%

Phase Distribution

19

Early Stage

13

Mid Stage

5

Late Stage

Phase Distribution37 total trials
Phase 1Safety & dosage
19(51.4%)
Phase 2Efficacy & side effects
13(35.1%)
Phase 3Large-scale testing
5(13.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

74.3%

26 of 35 finished

Non-Completion Rate

25.7%

9 ended early

Currently Active

4

trials recruiting

Total Trials

41

all time

Status Distribution
Active(6)
Completed(26)
Terminated(9)

Detailed Status

Completed26
Terminated8
Recruiting3
Not yet recruiting2
Active, not recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
41
Active
4
Success Rate
76.5%
Most Advanced
Phase 3

Trials by Phase

Phase 119 (51.4%)
Phase 213 (35.1%)
Phase 35 (13.5%)

Trials by Status

active_not_recruiting12%
completed2663%
withdrawn12%
not_yet_recruiting25%
recruiting37%
terminated820%

Recent Activity

Clinical Trials (41)

Showing 20 of 41 trialsScroll for more
NCT06948097Phase 1

Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies

Not Yet Recruiting
NCT05904093Phase 1

Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease

Recruiting
NCT06564207Phase 2

Fostamatinib for Treating Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Adults

Not Yet Recruiting
NCT06233110Phase 1

Ruxolitinib Plus Fostamatinib for Steroid Refractory cGvHD

Recruiting
NCT05502783Phase 2

Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated Cytopenias

Terminated
NCT04581954Phase 1

Inflammatory Signal Inhibitors for COVID-19 (MATIS)

Completed
NCT05509582Phase 2

Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias

Withdrawn
NCT05593770Phase 2

International Sites: Novel Experimental COVID-19 Therapies Affecting Host Response

Terminated
NCT05613296

Real World Evaluation of the Activity and Safety of Fostamatinib in Consecutive Adult Patients With ITP

Completed
NCT05030675Phase 1

Fostamatinib for the Treatment of Lower-risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia Who Have Failed Therapy With Hypomethylating Agents

Completed
NCT04924660Phase 2

Novel Experimental COVID-19 Therapies Affecting Host Response

Completed
NCT06757257

Special Drug Use-results Survey for Long-term Use (Fostamatinib)

Recruiting
NCT03991780Phase 1

Fostamatinib in the Treatment of Chronic Active Antibody Mediated Rejection

Active Not Recruiting
NCT04904276

Observational Study of Fostamatinib as Second Line Therapy in Adult Patients With Immune Thrombocytopenia (ITP) and Insufficient Response to a Prior Therapy

Terminated
NCT04543279Phase 2

Fostamatinib as a Single Agent or in Combination With Ruxolitinib for Treatment of Patients With Myelofibrosis With Severe Thrombocytopenia

Terminated
NCT06071520

Andalusian Experience in the Use of Fostamatinib in Patients With ITP. FOSTASUR Study

Completed
NCT04629703Phase 3

Double-Blind, Randomized, Placebo-Controlled, Multi-Center Phase 3 Study to Evaluate the Efficacy and Safety of Fostamatinib in COVID-19 Subjects

Completed
NCT02611063Phase 1

Evaluation of Fostamatinib in Patients With cGVHD After Allogeneic Stem Cell Transplant

Completed
NCT05040698Phase 2

Study of the Effect of Fostamatinib Upon Cutaneous Inflammation in the Setting of Hidradenitis Suppurativa

Completed
NCT04579393Phase 2

Fostamatinib for Hospitalized Adults With COVID-19

Completed

Drug Details

Intervention Type
DRUG
Total Trials
41