Success Metrics

Clinical Success Rate
88.9%

Based on 8 completed trials

Completion Rate
89%(8/9)
Active Trials
3(14%)
Results Posted
13%(1 trials)
Terminated
1(5%)

Phase Distribution

Ph phase_3
5
23%
Ph phase_2
16
73%

Phase Distribution

0

Early Stage

16

Mid Stage

5

Late Stage

Phase Distribution21 total trials
Phase 2Efficacy & side effects
16(76.2%)
Phase 3Large-scale testing
5(23.8%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

80.0%

8 of 10 finished

Non-Completion Rate

20.0%

2 ended early

Currently Active

3

trials recruiting

Total Trials

22

all time

Status Distribution
Active(4)
Completed(8)
Terminated(2)
Other(8)

Detailed Status

Completed8
unknown8
Recruiting3
Withdrawn1
Not yet recruiting1
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
22
Active
3
Success Rate
88.9%
Most Advanced
Phase 3

Trials by Phase

Phase 216 (76.2%)
Phase 35 (23.8%)

Trials by Status

completed836%
unknown836%
withdrawn15%
not_yet_recruiting15%
recruiting314%
terminated15%

Recent Activity

Clinical Trials (22)

Showing 20 of 22 trialsScroll for more
NCT07472868Phase 3

Neoadjuvant FOLFOXIRI and Chemoradiotherapy Versus Neoadjuvant CAPOX/FOLFOX and Chemoradiotherapy Followed by Surgery or a Watch-and-Wait Approach in High Risk Locally Advanced Rectal Cancer

Not Yet Recruiting
NCT04380337Phase 2

Organ Preservation Program Using Short-Course Radiation & FOLFOXIRI in Rectal Cancer

Completed
NCT03117972Phase 2

Chemotherapy Intensification in Patients With High Lactate Dehydrogenase Values and Soluble Syndecan1 Levels

Terminated
NCT06242418Phase 2

CtDNA in Adjuvant Chemotherapy of Stage III Colon Cancer (REVISE Trial)

Recruiting
NCT01328171Phase 2

FOLFOXIRI With or Without Panitumumab in Metastatic Colorectal Cancer (VOLFI)

Completed
NCT05201430Phase 3

Neoadjuvant FOLFOXIRI Versus CapeOX Chemotherapy for Local Advanced Rectal Cancer

Recruiting
NCT03484195Phase 2

Neoadjuvant FOLFOXIRI Chemotherapy in Patients With Locally Advanced Colon Cancer

Unknown
NCT03487939Phase 2

Neoadjuvant FOLFOXIRI Chemotherapy in Resectable Liver Metastasis of Colorectal Cancer

Unknown
NCT02217020Phase 2

Neoadjuvant FOLFOXIRI Chemotherapy Alone for Locally Advanced Rectal Cancer

Completed
NCT03484221Phase 2

Totally Neoadjuvant FOLFOXIRI + Short-course Radiation + XELOX in Patients With Locally Advanced Rectal Cancer

Unknown
NCT04832776Phase 2

FOLFOXIRI Plus Cetuximab Versus FOLFOXIRI Plus Bevacizumab in Conversion Therapy of Right-sided Colon Cancer Liver Metastases

Unknown
NCT03443661Phase 2

Neoadjuvant Triplet Chemotherapy Regimen in Patients With Locally Advanced Rectal Cancer

Completed
NCT02063529Phase 2

FOLFOXIRI With or Without Cetuximab as First-line Treatment of Patients With Non-resectable Liver - Only Metastatic Colorectal Cancer

Completed
NCT03161574Phase 2

FOLFOXIRI Chemotherapy Alone as Neoadjuvant Treatment for Circumferential Radial Margin (CRM) Positive Rectal Cancer

Withdrawn
NCT03671252Phase 3

Prospectively Randomized Control Clinical Trial of FOLFOXIRI Preoperative Chemotherapy Alone on Rectal Cancer in Local Advance Comparing to Oral Capecitabine Combined With Long-term Radiation

Recruiting
NCT03504618

Research on the Treatment of Metastatic Colon Cancer Patients Treated by FOLFOXIRI

Completed
NCT02942563Phase 2

Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer

Unknown
NCT02350530Phase 2

FOLFOXIRI With or Without Bevacizumab as First-line Treatment for Unresectable Liver-only Metastatic Colorectal Cancer Patients With RAS Mutation-type

Unknown
NCT01219920Phase 3

FOLFOXIRI Compared With FOLFIRI for Metastatic Colorectal Cancer

Completed
NCT02355119Phase 3

Italian Multicenter Study Comparing FOLFOXIRI Versus Gemcitabine as Adjuvant Treatment for Resected Pancreatic Cancer

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
22