Success Metrics

Clinical Success Rate
77.8%

Based on 14 completed trials

Completion Rate
78%(14/18)
Active Trials
3(10%)
Results Posted
21%(3 trials)
Terminated
4(13%)

Phase Distribution

Ph not_applicable
1
3%
Ph phase_2
11
35%
Ph phase_3
15
48%
Ph phase_1
4
13%

Phase Distribution

4

Early Stage

11

Mid Stage

15

Late Stage

Phase Distribution31 total trials
Phase 1Safety & dosage
4(12.9%)
Phase 2Efficacy & side effects
11(35.5%)
Phase 3Large-scale testing
15(48.4%)
N/ANon-phased studies
1(3.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

73.7%

14 of 19 finished

Non-Completion Rate

26.3%

5 ended early

Currently Active

3

trials recruiting

Total Trials

31

all time

Status Distribution
Active(3)
Completed(14)
Terminated(5)
Other(9)

Detailed Status

Completed14
unknown9
Terminated4
Active, not recruiting2
Recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
31
Active
3
Success Rate
77.8%
Most Advanced
Phase 3

Trials by Phase

Phase 14 (12.9%)
Phase 211 (35.5%)
Phase 315 (48.4%)
N/A1 (3.2%)

Trials by Status

recruiting13%
terminated413%
unknown929%
withdrawn13%
active_not_recruiting26%
completed1445%

Recent Activity

Clinical Trials (31)

Showing 20 of 31 trialsScroll for more
NCT04793958Phase 3

Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10)

Active Not Recruiting
NCT06252649Phase 3

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

Recruiting
NCT05983367Phase 2

A Study to Investigate Ompenaclid Combined With FOLFIRI Plus Bevacizumab in Advanced/Metastatic Colorectal Cancer

Terminated
NCT01167725Phase 3

Standard Therapy With or Without Surgery and Mitomycin C in Treating Patients With Advanced Limited Peritoneal Dissemination of Colon Cancer

Terminated
NCT03635021Phase 3

Study to Evaluate the Efficacy of FOLFOX + Panitumumab Followed by FOLFIRI + Bevacizumab (Sequence 1) Versus FOLFOX + Bevacizumab Followed by FOLFIRI + Panitumumab (Sequence 2) in Untreated Patients With Wild-type RAS Metastatic, Primary Left-sided, Unresectable Colorectal Cancer

Active Not Recruiting
NCT04926545Not Applicable

XCHT for Irinotecan-Induced Gut Toxicities (Run-in Study)

Completed
NCT00936832Phase 2

Sunitinib Malate and Combination Chemotherapy as Front-Line Therapy in Treating Patients With Metastatic Rectal Cancer That Cannot Be Removed by Surgery

Withdrawn
NCT05193292Phase 2

Camrelizumab Combined With Trastuzumab and Chemotherapy in Patients With HER2-positive Advanced Colorectal Cancer

Unknown
NCT00066274Phase 2

Comparison of Combination Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer

Completed
NCT00005979Phase 3

Combination Chemotherapy With or Without Irinotecan in Treating Patients With Stage III Colon Cancer

Completed
NCT00023868Phase 3

Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655)

Terminated
NCT00952029Phase 2

Combination Chemotherapy and Bevacizumab With or Without Bevacizumab Maintenance Therapy in Treating Patients With Metastatic Colorectal Cancer

Completed
NCT00497497Phase 1

A Study of PRO95780 in Combination With Cetuximab and Irinotecan Chemotherapy or the FOLFIRI Regimen With Bevacizumab in Patients With Previously Treated Metastatic Colorectal Cancer (APM4187g)

Completed
NCT00671372Phase 1

A Study of Dulanermin Administered in Combination With Camptosar®/Erbitux® Chemotherapy or FOLFIRI (With or Without Bevacizumab) in Subjects With Previously Treated Metastatic Colorectal Cancer

Completed
NCT01937715Phase 1

A Study Of PF-05212384 Plus FOLFIRI Versus Bevacizumab Plus FOLFIRI In Metastatic Colorectal Cancer

Terminated
NCT00440310Phase 3

Phase 3 Trial of Litx™ Plus Chemotherapy vs. Chemotherapy Only Treating Colorectal Cancer Patients With Recurrent Liver Metastases

Completed
NCT00020488Phase 1

Combination Chemotherapy in Treating Patients Who Have Advanced Solid Tumors

Completed
NCT01205711Phase 2

Irinotecan Hydrochloride, Fluorouracil, and Leucovorin Calcium With or Without Zibotentan in Treating Patients With Metastatic Colorectal Cancer

Completed
NCT00027833Phase 2

Vaccine Therapy and Chemotherapy With or Without Tetanus Toxoid Compared With Chemotherapy Alone in Treating Patients With Metastatic Colorectal Cancer

Unknown
NCT00005607Phase 2

Combination Chemotherapy in Treating Patients With Metastatic or Recurrent Cancer of the Stomach or Esophagus

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
31