Success Metrics

Clinical Success Rate
94.4%

Based on 17 completed trials

Completion Rate
94%(17/18)
Active Trials
12(24%)
Results Posted
0%(0 trials)
Terminated
1(2%)

Phase Distribution

Ph phase_1
17
35%
Ph phase_2
25
51%
Ph phase_3
7
14%

Phase Distribution

17

Early Stage

25

Mid Stage

7

Late Stage

Phase Distribution49 total trials
Phase 1Safety & dosage
17(34.7%)
Phase 2Efficacy & side effects
25(51.0%)
Phase 3Large-scale testing
7(14.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

94.4%

17 of 18 finished

Non-Completion Rate

5.6%

1 ended early

Currently Active

12

trials recruiting

Total Trials

49

all time

Status Distribution
Active(19)
Completed(17)
Terminated(1)
Other(12)

Detailed Status

Completed17
Recruiting11
unknown11
Not yet recruiting7
Suspended1
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
49
Active
12
Success Rate
94.4%
Most Advanced
Phase 3

Trials by Phase

Phase 117 (34.7%)
Phase 225 (51.0%)
Phase 37 (14.3%)

Trials by Status

suspended12%
recruiting1122%
terminated12%
active_not_recruiting12%
completed1735%
not_yet_recruiting714%
unknown1122%

Recent Activity

Clinical Trials (49)

Showing 20 of 49 trialsScroll for more
NCT05656131Phase 2

Fluzoparib in Combination With or Without Camrelizumab for Homologous Recombinant Deficiency (HRD) HER2 Negative Advanced Breast Cancer

Suspended
NCT07382713Phase 2

Fluzoparib Plus Famitinib Maintenance After First-Line Platinum Response in Advanced Ovarian Cancer

Not Yet Recruiting
NCT07353437Phase 2

Fluzoparib as Adjuvant Treatment in Patients With Germline Homologous Recombination Repair (HRR) Mutated Primary Breast Cancer (Flamenco)

Not Yet Recruiting
NCT05938374Phase 2

Preoperative Moderately Fractionated IMRT for Locally Extremity or Trunk Sarcoma (SPARE-03)

Completed
NCT07141771Phase 1

An Umbrella Study of Recurrent, Extensive Stage Small Cell Lung Cancer Based on Molecular Typing

Not Yet Recruiting
NCT05582499Phase 2

Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy

Recruiting
NCT06255392Phase 3

Randomized, Open, Controlled, Multicenter Phase III Clinical Study of Fluzoparib in Combination With Apatinib Versus Investigator-Selected Chemotherapy for HRD-Positive/HER2-negative Advanced Breast Cancer

Recruiting
NCT04400188Phase 1

A Study of Fluzoparib (SHR-3162) and Temozolomide With or Without SHR-1316 in Treating Patients With Replapsed Small Cell Lung Cancer

Completed
NCT05894018Phase 2

Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcoma

Recruiting
NCT04694365Phase 1

Safety and Pharmacokinetics of Fluzoparib in Healthy Subjects and Those With Impaired Liver Function

Completed
NCT04517357Phase 2

A Phase 2 Trial of Fluzoparib Combined With Apatinib Versus Fluzoparib Monotherapy in Treatment With Relapsed Ovarian Cancer Patients

Completed
NCT04869488Phase 2

A Trial of SHR3162 Combined With Apatinib Mesylate Tablets or SHR3162 Monotherapy in Patients With Metastatic Castration Resistant Prostate Cancer

Completed
NCT06735326Phase 2

Fluzoparib With or Without Bevacizumab for Neoadjuvant Therapy in Advanced Ovarian Cancer

Recruiting
NCT06541314Phase 2

Fluzoparib Neoadjuvant Therapy for Ovarian Cancer

Recruiting
NCT05594095Phase 2

SNF Platform Study of HR+/ HER2-advanced Breast Cancer

Recruiting
NCT06612814Phase 3

PARP Inhibitor With CDK4/ 6 Inhibitor and Endocrine Therapy in HR+/ HER2-Advanced Breast Cancer

Active Not Recruiting
NCT06561022Phase 2

Precision Treatment of HR+ HER2- Advanced Breast Cancer Based on SNF Molecular Subtyping

Not Yet Recruiting
NCT04228601Phase 1

A Study of Fluzoparib in Combination With mFOLFIRINOX in Patients With Advanced Pancreatic Cancer

Completed
NCT06552858Phase 2

Fluzoparib Combined With Dalpiciclib for Platinum Resistant Recurrent Ovarian Cancer

Not Yet Recruiting
NCT06539091Phase 3

Fluzoparib in Combination With Apatinib Mesylate for Maintenance Therapy in Stage III-IV Ovarian Cancer

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
49