Success Metrics

Clinical Success Rate
88.2%

Based on 15 completed trials

Completion Rate
88%(15/17)
Active Trials
1(5%)
Results Posted
20%(3 trials)
Terminated
2(9%)

Phase Distribution

Ph phase_2
2
9%
Ph phase_4
4
18%
Ph phase_1
6
27%
Ph not_applicable
8
36%
Ph early_phase_1
2
9%

Phase Distribution

8

Early Stage

2

Mid Stage

4

Late Stage

Phase Distribution22 total trials
Early Phase 1First-in-human
2(9.1%)
Phase 1Safety & dosage
6(27.3%)
Phase 2Efficacy & side effects
2(9.1%)
Phase 4Post-market surveillance
4(18.2%)
N/ANon-phased studies
8(36.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

78.9%

15 of 19 finished

Non-Completion Rate

21.1%

4 ended early

Currently Active

1

trials recruiting

Total Trials

22

all time

Status Distribution
Active(2)
Completed(15)
Terminated(4)
Other(1)

Detailed Status

Completed15
Withdrawn2
Terminated2
unknown1
Recruiting1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
22
Active
1
Success Rate
88.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (9.1%)
Phase 16 (27.3%)
Phase 22 (9.1%)
Phase 44 (18.2%)
N/A8 (36.4%)

Trials by Status

withdrawn29%
unknown15%
recruiting15%
terminated29%
completed1568%
not_yet_recruiting15%

Recent Activity

Clinical Trials (22)

Showing 20 of 22 trialsScroll for more
NCT05939674Not Applicable

Effects of Flumazenil on Recovery After Total Intravenous Anesthesia With Remimazolam

Recruiting
NCT03743805Early Phase 1

Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination

Withdrawn
NCT06563063Not Applicable

Finding ED90 of Flumazenil for Selective Improvement of Respiratory Distress by Remimazolam

Completed
NCT06513923Phase 4

Comparison of Remimazolam and Propofol on Emergence in Elderly Orthopedic Patients Under General Anesthesia

Completed
NCT06205719Early Phase 1

Effect of Remazolam on Anesthesia Recovery in Patients Undergoing Fundus Surgery

Not Yet Recruiting
NCT05397886Not Applicable

Comparison of Remimazolam With Flumazenil vs. Propofol During RFCA for Atrial Fibrillation

Completed
NCT05681377Phase 4

Impact of Flumazenil on the Emergence Delirium

Completed
NCT05382806Not Applicable

Reversal of Remimazolam by a Single Dose of Flumazenil

Completed
NCT05435911Not Applicable

Comparison of Recovery From General Anesthesia in Remimazolam With Flumazenil vs. Propofol

Completed
NCT05468671Phase 4

Clinical Application Value of Remazolam Combined With Sugammadex Sodium in Anesthesia for Endotracheal Surgery Under Bronchoscopy

Completed
NCT03462641Phase 1

Modulation of GABA-A Receptors in Parkinson Disease-Flumazenil Arm

Completed
NCT02899156Phase 4

Flumazenil for Hypoactive Delirium Secondary to Benzodiazepine Exposure

Terminated
NCT02048969Phase 1

Treatment of Hepatic Encephalopathy With Flumazenil and Change in Cortical GABA Levels in MRS

Withdrawn
NCT04329585Not Applicable

GABA Antagonist to Improve Reversal of Anesthesia With High-density EEG Surveillance

Unknown
NCT01183312Phase 1

Flumazenil for the Treatment of Primary Hypersomnia

Completed
NCT00000246Phase 2

Rapid Benzodiazepine Detoxification Using Flumazenil - 1

Completed
NCT02690389Not Applicable

Electro-acupuncture and Flumazenil's Effect on Sedation

Completed
NCT01655914Phase 1

Safety and Pharmacokinetic Study of Sublingual Flumazenil (CRLS035) in Healthy Adults

Completed
NCT01071889Phase 1

Safety and the Efficacy of a Sublingual Administration of Flumazenil to Reverse the Effect of Hypnotic Drugs in Healthy Adults

Completed
NCT02157428Not Applicable

Effect of Flumazenil on Recovery From General Anesthesia With Isoflurane

Completed

Drug Details

Intervention Type
DRUG
Total Trials
22