Success Metrics

Clinical Success Rate
62.8%

Based on 304 completed trials

Completion Rate
63%(304/484)
Active Trials
339(33%)
Results Posted
98%(299 trials)
Terminated
180(18%)

Phase Distribution

Ph phase_3
55
5%
Ph phase_4
15
1%
Ph phase_2
337
33%
Ph not_applicable
31
3%
Ph early_phase_1
33
3%
Ph phase_1
539
53%

Phase Distribution

572

Early Stage

337

Mid Stage

70

Late Stage

Phase Distribution1010 total trials
Early Phase 1First-in-human
33(3.3%)
Phase 1Safety & dosage
539(53.4%)
Phase 2Efficacy & side effects
337(33.4%)
Phase 3Large-scale testing
55(5.4%)
Phase 4Post-market surveillance
15(1.5%)
N/ANon-phased studies
31(3.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

56.8%

304 of 535 finished

Non-Completion Rate

43.2%

231 ended early

Currently Active

339

trials recruiting

Total Trials

1,019

all time

Status Distribution
Active(384)
Completed(304)
Terminated(231)
Other(100)

Detailed Status

Completed304
Recruiting228
Terminated180
Active, not recruiting111
unknown94
Withdrawn51

Development Timeline

Analytics

Development Status

Total Trials
1019
Active
339
Success Rate
62.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 133 (3.3%)
Phase 1539 (53.4%)
Phase 2337 (33.4%)
Phase 355 (5.4%)
Phase 415 (1.5%)
N/A31 (3.1%)

Trials by Status

active_not_recruiting11111%
terminated18018%
enrolling_by_invitation20%
completed30430%
withdrawn515%
recruiting22822%
suspended61%
not_yet_recruiting434%
unknown949%

Recent Activity

Clinical Trials (1,019)

Showing 20 of 1,019 trialsScroll for more
NCT07569965Phase 2

Frontline Risk-Adapted Optimization of Novel Targeted Immunotherapy Evaluation in High-Risk MCL

Not Yet Recruiting
NCT07509034Phase 1

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

Not Yet Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT05922930Phase 1

Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic Cancer

Recruiting
NCT04872595Phase 2

A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant

Active Not Recruiting
NCT06500273Phase 2

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

Recruiting
NCT07328503Phase 2

CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia

Not Yet Recruiting
NCT07164469Phase 2

Phase 2 Trial of CD70.CAR NK Cells for Patients With Primary Refractory or Early Relapsed Diffuse Large B-Cell Lymphoma and Hodgkin Lymphoma

Not Yet Recruiting
NCT07524530Phase 2

Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers

Not Yet Recruiting
NCT07101432Phase 1

Phase I Study of Preconditioning Radiation Therapy With IL-15 Transduced TGFBR2 KO CAR.TROP2-engineered Cord Blood-derived NK Cells in Patients With Advanced Head and Neck Cancer (RADIANCE-NK)

Recruiting
NCT06930651Phase 1

A Phase I/II Study of CAR.70-Engineered IL15-Transduced Cord Blood-Derived NK Cells With TGF-beta Receptor 2 (TGFBR2) Knock Out in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Myeloid Malignancies

Recruiting
NCT04217278Phase 2

A Trial of Treatments to Assess the Effects on Outcome of Adults With AML and MDS Undergoing Allogeneic SCT

Active Not Recruiting
NCT07509008Phase 1

Phase 1/2 Window Of Opportunity Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cells Delivered Intraperitoneally For The Management Of Gastric Cancer Metastatic To The Peritoneum

Not Yet Recruiting
NCT05146739Phase 1

Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell Membrane

Active Not Recruiting
NCT02133196Phase 2

T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer

Recruiting
NCT07566377Phase 2

Cord Blood Transplantation in Children and Young Adults With Blood Cancer

Recruiting
NCT05400109Phase 1

Evaluate the Safety of UF-KURE19 Cells in Non-Hodgkin Lymphomas

Active Not Recruiting
NCT03182244Phase 3

A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase 3 (FLT3) Mutation

Active Not Recruiting
NCT03821610Phase 2

A Comparison of Reduced Dose Total Body Irradiation (TBI) and Cyclophosphamide With Fludarabine and Melphalan Reduced Intensity Conditioning in Adults With Acute Lymphoblastic Leukaemia (ALL) in Complete Remission. (ALL-RIC)

Active Not Recruiting
NCT06158828Phase 1

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,019