Success Metrics

Clinical Success Rate
62.6%

Based on 309 completed trials

Completion Rate
63%(309/494)
Active Trials
346(33%)
Results Posted
98%(303 trials)
Terminated
185(18%)

Phase Distribution

Ph early_phase_1
33
3%
Ph not_applicable
31
3%
Ph phase_1
558
53%
Ph phase_2
344
33%
Ph phase_3
56
5%
Ph phase_4
15
1%

Phase Distribution

591

Early Stage

344

Mid Stage

71

Late Stage

Phase Distribution1037 total trials
Early Phase 1First-in-human
33(3.2%)
Phase 1Safety & dosage
558(53.8%)
Phase 2Efficacy & side effects
344(33.2%)
Phase 3Large-scale testing
56(5.4%)
Phase 4Post-market surveillance
15(1.4%)
N/ANon-phased studies
31(3.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

56.5%

309 of 547 finished

Non-Completion Rate

43.5%

238 ended early

Currently Active

346

trials recruiting

Total Trials

1,047

all time

Status Distribution
Active(395)
Completed(309)
Terminated(238)
Other(105)

Detailed Status

Completed309
Recruiting238
Terminated185
Active, not recruiting108
unknown95
Withdrawn53

Development Timeline

Analytics

Development Status

Total Trials
1047
Active
346
Success Rate
62.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 133 (3.2%)
Phase 1558 (53.8%)
Phase 2344 (33.2%)
Phase 356 (5.4%)
Phase 415 (1.4%)
N/A31 (3.0%)

Trials by Status

active_not_recruiting10810%
enrolling_by_invitation20%
not_yet_recruiting474%
recruiting23823%
completed30930%
terminated18518%
unknown959%
withdrawn535%
suspended101%

Recent Activity

Clinical Trials (1,047)

Showing 20 of 1,047 trialsScroll for more
NCT07572136Phase 1

Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Not Yet Recruiting
NCT03696784Phase 1

Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma

Active Not Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT07085104Phase 1

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

Recruiting
NCT07524530Phase 2

Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers

Not Yet Recruiting
NCT07672483Phase 1

IL-12 Genetically Engineered Myeloid Cells in Participants With Relapsed, Refractory Solid Tumors

Not Yet Recruiting
NCT06287944Phase 1

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Recruiting
NCT07509034Phase 1

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

Not Yet Recruiting
NCT05442515Phase 1

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

Recruiting
NCT05457556Phase 3

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Active Not Recruiting
NCT07737769Phase 1

Arsenic Trioxide to Prevent Relapse in Patients Undergoing Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia or Myelodysplastic Syndrome

Not Yet Recruiting
NCT07735637Phase 3

A Phase III, Multicentre Study to Evaluate Consolidation Treatment With AZD0120 Compared With ASCT, in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible (DURGA-6).

Not Yet Recruiting
NCT06500273Phase 2

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

Recruiting
NCT07137481Phase 2

Phase II Study of CD5 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Aggressive T Cell Hematological Malignancies

Not Yet Recruiting
NCT05600426Phase 3

A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)

Active Not Recruiting
NCT05922930Phase 1

Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic Cancer

Suspended
NCT05327023Phase 1

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

Recruiting
NCT06413498Phase 3

A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

Active Not Recruiting
NCT06034470Phase 1

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

Active Not Recruiting
NCT07509008Phase 1

Phase 1/2 Window Of Opportunity Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cells Delivered Intraperitoneally For The Management Of Gastric Cancer Metastatic To The Peritoneum

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,047