Success Metrics

Clinical Success Rate
62.4%

Based on 309 completed trials

Completion Rate
62%(309/495)
Active Trials
344(33%)
Results Posted
98%(304 trials)
Terminated
186(18%)

Phase Distribution

Ph phase_2
344
33%
Ph early_phase_1
33
3%
Ph not_applicable
31
3%
Ph phase_1
558
53%
Ph phase_3
56
5%
Ph phase_4
15
1%

Phase Distribution

591

Early Stage

344

Mid Stage

71

Late Stage

Phase Distribution1037 total trials
Early Phase 1First-in-human
33(3.2%)
Phase 1Safety & dosage
558(53.8%)
Phase 2Efficacy & side effects
344(33.2%)
Phase 3Large-scale testing
56(5.4%)
Phase 4Post-market surveillance
15(1.4%)
N/ANon-phased studies
31(3.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

56.3%

309 of 549 finished

Non-Completion Rate

43.7%

240 ended early

Currently Active

344

trials recruiting

Total Trials

1,047

all time

Status Distribution
Active(393)
Completed(309)
Terminated(240)
Other(105)

Detailed Status

Completed309
Recruiting233
Terminated186
Active, not recruiting111
unknown95
Withdrawn54

Development Timeline

Analytics

Development Status

Total Trials
1047
Active
344
Success Rate
62.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 133 (3.2%)
Phase 1558 (53.8%)
Phase 2344 (33.2%)
Phase 356 (5.4%)
Phase 415 (1.4%)
N/A31 (3.0%)

Trials by Status

enrolling_by_invitation20%
completed30930%
withdrawn545%
active_not_recruiting11111%
not_yet_recruiting474%
recruiting23322%
suspended101%
unknown959%
terminated18618%

Recent Activity

Clinical Trials (1,047)

Showing 20 of 1,047 trialsScroll for more
NCT06940297Phase 2

Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma

Recruiting
NCT07572136Phase 1

Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Not Yet Recruiting
NCT07672483Phase 1

IL-12 Genetically Engineered Myeloid Cells in Participants With Relapsed, Refractory Solid Tumors

Not Yet Recruiting
NCT07524530Phase 2

Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers

Not Yet Recruiting
NCT07509034Phase 1

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

Not Yet Recruiting
NCT06237881Phase 1

A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors

Active Not Recruiting
NCT06486051Phase 2

A Study of Atlacabtagene Autoleucel CAR T-cells for Adults With Relapsed Large B-cell Lymphoma

Recruiting
NCT03190941Phase 1

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients

Recruiting
NCT06733935Phase 1

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

Recruiting
NCT01174121Phase 2

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer

Recruiting
NCT05020444Phase 1

TriPRIL CAR T Cells in Multiple Myeloma

Active Not Recruiting
NCT06609928Phase 1

FH-FOLR1 Chimeric Antigen Receptor T Cell Therapy for Treating Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recruiting
NCT04994808Phase 2

Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid Leukemia

Terminated
NCT02861417Phase 2

Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant

Active Not Recruiting
NCT06984341Phase 1

A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Pharmacodynamics, and Efficacy of P-CD19CD20-ALLO1 in Participants With Severe, Treatment-refractory Systemic Lupus Erythematosus (SLE)

Withdrawn
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT07162038Phase 1

Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation

Recruiting
NCT02498912Phase 1

Cyclophosphamide Followed by Intravenous and Intraperitoneal Infusion of Autologous T Cells Genetically Engineered to Secrete IL-12 and to Target the MUC16ecto Antigen in Patients With Recurrent MUC16ecto+ Solid Tumors

Active Not Recruiting
NCT07335562Phase 3

A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis

Not Yet Recruiting
NCT07297667Phase 1

GCAR1, a Chimeric Antigen Receptor (CAR) T-CELL Therapy for Relapsed/Refractory GPNMB-Expressing Solid Tumours

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,047