Success Metrics

Clinical Success Rate
84.3%

Based on 557 completed trials

Completion Rate
84%(557/661)
Active Trials
52(6%)
Results Posted
40%(222 trials)
Terminated
104(13%)

Phase Distribution

Ph phase_1
236
29%
Ph early_phase_1
6
1%
Ph phase_2
390
48%
Ph phase_4
7
1%
Ph phase_3
130
16%
Ph not_applicable
36
4%

Phase Distribution

242

Early Stage

390

Mid Stage

137

Late Stage

Phase Distribution805 total trials
Early Phase 1First-in-human
6(0.7%)
Phase 1Safety & dosage
236(29.3%)
Phase 2Efficacy & side effects
390(48.4%)
Phase 3Large-scale testing
130(16.1%)
Phase 4Post-market surveillance
7(0.9%)
N/ANon-phased studies
36(4.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

81.0%

557 of 688 finished

Non-Completion Rate

19.0%

131 ended early

Currently Active

52

trials recruiting

Total Trials

810

all time

Status Distribution
Active(57)
Completed(557)
Terminated(131)
Other(65)

Detailed Status

Completed557
Terminated104
unknown64
Recruiting30
Withdrawn27
Active, not recruiting22

Development Timeline

Analytics

Development Status

Total Trials
810
Active
52
Success Rate
84.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 16 (0.7%)
Phase 1236 (29.3%)
Phase 2390 (48.4%)
Phase 3130 (16.1%)
Phase 47 (0.9%)
N/A36 (4.5%)

Trials by Status

terminated10413%
unknown648%
completed55769%
enrolling_by_invitation10%
withdrawn273%
recruiting304%
not_yet_recruiting40%
active_not_recruiting223%
suspended10%

Recent Activity

Clinical Trials (810)

Showing 20 of 810 trialsScroll for more
NCT07012044Phase 1

A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

Recruiting
NCT02015013Phase 2

Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Recruiting
NCT05436418Phase 1

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Recruiting
NCT06325709Phase 1

Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease

Recruiting
NCT04959175Phase 1

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

Recruiting
NCT03247088Phase 1

Sorafenib, Busulfan and Fludarabine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant

Active Not Recruiting
NCT06942039Early Phase 1

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

Recruiting
NCT00392327Phase 3

Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET

Completed
NCT07604233Phase 1

Phase 1/2 FLAG-IDA, VEN and Asciminib in CML and Ph+ AML

Not Yet Recruiting
NCT01553214Phase 4

Improving White Blood Cell Collection From Healthy Donors

Recruiting
NCT07278856Phase 1

Ruxolitinib in Combination With CHOP Chemotherapy for the Treatment of Untreated Nodal T-Follicular Helper Cell Lymphomas

Recruiting
NCT07059611Phase 2

Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma

Not Yet Recruiting
NCT04759586Phase 3

Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma

Active Not Recruiting
NCT07052370Phase 1

TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies

Recruiting
NCT03907488Phase 3

Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

Active Not Recruiting
NCT04250051Phase 1

Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia

Terminated
NCT06851767Phase 1

Base-Edited Hematopoietic Stem/Progenitor Cell X-Linked Severe Combined Immunodeficiency Gene Therapy

Enrolling By Invitation
NCT07616154Phase 2

Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease

Not Yet Recruiting
NCT04195633Phase 2

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

Recruiting
NCT00792948Phase 2

Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
810