Success Metrics

Clinical Success Rate
84.3%

Based on 557 completed trials

Completion Rate
84%(557/661)
Active Trials
53(7%)
Results Posted
40%(223 trials)
Terminated
104(13%)

Phase Distribution

Ph phase_4
7
1%
Ph phase_3
130
16%
Ph phase_2
391
48%
Ph phase_1
236
29%
Ph not_applicable
36
4%
Ph early_phase_1
6
1%

Phase Distribution

242

Early Stage

391

Mid Stage

137

Late Stage

Phase Distribution806 total trials
Early Phase 1First-in-human
6(0.7%)
Phase 1Safety & dosage
236(29.3%)
Phase 2Efficacy & side effects
391(48.5%)
Phase 3Large-scale testing
130(16.1%)
Phase 4Post-market surveillance
7(0.9%)
N/ANon-phased studies
36(4.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

81.0%

557 of 688 finished

Non-Completion Rate

19.0%

131 ended early

Currently Active

53

trials recruiting

Total Trials

811

all time

Status Distribution
Active(58)
Completed(557)
Terminated(131)
Other(65)

Detailed Status

Completed557
Terminated104
unknown64
Recruiting31
Withdrawn27
Active, not recruiting22

Development Timeline

Analytics

Development Status

Total Trials
811
Active
53
Success Rate
84.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 16 (0.7%)
Phase 1236 (29.3%)
Phase 2391 (48.5%)
Phase 3130 (16.1%)
Phase 47 (0.9%)
N/A36 (4.5%)

Trials by Status

enrolling_by_invitation10%
recruiting314%
suspended10%
withdrawn273%
active_not_recruiting223%
completed55769%
unknown648%
terminated10413%
not_yet_recruiting40%

Recent Activity

Clinical Trials (811)

Showing 20 of 811 trialsScroll for more
NCT03147612Phase 2

Low-Intensity Chemotherapy, Ponatinib and Blinatumomab in Treating Patients With Philadelphia Chromosome-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT06325709Phase 1

Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease

Recruiting
NCT01553214Phase 4

Improving White Blood Cell Collection From Healthy Donors

Recruiting
NCT07012044Phase 1

A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

Recruiting
NCT03907488Phase 3

Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

Active Not Recruiting
NCT02015013Phase 2

Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Recruiting
NCT00006436Phase 2

EPOCH and Rituximab to Treat Non-Hodgkin's Lymphoma in Patients With HIV Infection

Completed
NCT00334815Phase 2

Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Active Not Recruiting
NCT00792948Phase 2

Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT07616154Phase 2

Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease

Recruiting
NCT07064018Phase 1

Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

Recruiting
NCT07257419Phase 1

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

Recruiting
NCT06942039Early Phase 1

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

Recruiting
NCT04759586Phase 3

Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma

Active Not Recruiting
NCT06738368Phase 2

Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia

Recruiting
NCT01783535Phase 2

Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma

Active Not Recruiting
NCT03220022Phase 1

Ibrutinib, Rituximab, Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell Lymphomas

Active Not Recruiting
NCT01012297Phase 3

Gemcitabine Hydrochloride and Docetaxel With or Without Bevacizumab in Treating Patients With Advanced or Recurrent Uterine Leiomyosarcoma

Terminated
NCT01624805Phase 2

Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome

Recruiting
NCT03755804Phase 2

Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17

Active Not Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
811