Success Metrics

Clinical Success Rate
82.4%

Based on 14 completed trials

Completion Rate
82%(14/17)
Active Trials
1(4%)
Results Posted
64%(9 trials)
Terminated
3(13%)

Phase Distribution

Ph phase_4
10
43%
Ph phase_1
2
9%
Ph not_applicable
1
4%
Ph phase_3
6
26%
Ph phase_2
2
9%

Phase Distribution

2

Early Stage

2

Mid Stage

16

Late Stage

Phase Distribution21 total trials
Phase 1Safety & dosage
2(9.5%)
Phase 2Efficacy & side effects
2(9.5%)
Phase 3Large-scale testing
6(28.6%)
Phase 4Post-market surveillance
10(47.6%)
N/ANon-phased studies
1(4.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

70.0%

14 of 20 finished

Non-Completion Rate

30.0%

6 ended early

Currently Active

1

trials recruiting

Total Trials

23

all time

Status Distribution
Active(3)
Completed(14)
Terminated(6)

Detailed Status

Completed14
Withdrawn3
Terminated3
Not yet recruiting2
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
23
Active
1
Success Rate
82.4%
Most Advanced
Phase 4

Trials by Phase

Phase 12 (9.5%)
Phase 22 (9.5%)
Phase 36 (28.6%)
Phase 410 (47.6%)
N/A1 (4.8%)

Trials by Status

withdrawn313%
completed1461%
terminated313%
not_yet_recruiting29%
recruiting14%

Recent Activity

Clinical Trials (23)

Showing 20 of 23 trialsScroll for more
NCT07328971Phase 3

Vancomycin Taper to Prevent Recurrent Clostridioides Difficile

Recruiting
NCT02667418Phase 4

Optimal Treatment for Recurrent Clostridium Difficile

Terminated
NCT06794944Phase 4

Use of Fidaxomicin Compared to Vancomycin for Decolonization of C. Difficile in Patients With Inflammatory Bowel Disease

Not Yet Recruiting
NCT07120490Not Applicable

STOP-CDI: Efficacy of Fecal Microbiota Transplantation vs Fidaxomicin vs Vancomycin in Treating and Preventing Relapse of Clostridioides Difficile Infection

Not Yet Recruiting
NCT05201079Phase 3

Primary or Recurrent Clostridioides Difficile Infection Treatment With Capsules of Lyophilised Faecal Microbiota vs Fidaxomicin

Completed
NCT02254967Phase 4

A Phase IIIB/IV Study to Compare the Efficacy of Vancomycin Therapy to Extended Duration of Fidaxomicin Therapy in the Clinical Cure of Clostridium Difficile Infection (CDI) in an Older Population

Completed
NCT02437591Phase 4

Study to Evaluate the Pharmacokinetics of Fidaxomicin in Inflammatory Bowel Disease (IBD) Subjects With Clostridium Difficile Infection (CDI)

Completed
NCT04070352

Evaluation of Fidaxomicin in the Treatment of Clostridium Difficile Infection (CDI)

Withdrawn
NCT02395848Phase 3

Efficacy of 30-day Duration of Fidaxomicin for Recurrent C. Difficile Infection

Terminated
NCT02692651Phase 4

A Comparison of Fidaxomicin and Vancomycin in Patients With CDI Receiving Antibiotics for Concurrent Infections

Completed
NCT01775397Phase 4

A Post-marketing, Blinded Study to Investigate How Effective Fidaxomicin is Compared to Vancomycin in the Sustained Cure of Clostridium Difficile Infection in Adults That Are Receiving Therapy to Suppress the Immune System

Terminated
NCT02743234Phase 3

Fecal Microbiota Transplantation for Relapsing Clostridium Difficile Infection

Completed
NCT02057198Phase 4

Impact of Oral Antibiotic Treatment on C. Difficile

Completed
NCT01591863Phase 2

Safety, Tolerability, and Pharmacokinetics of Fidaxomicin in Pediatric Subjects With Clostridium Difficile-associated Diarrhea (CDAD)

Completed
NCT01691248Phase 3

Safety and Efficacy of Fidaxomicin Versus Placebo for Prophylaxis Against Clostridium Difficile-Associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation (MK-5119-001)

Completed
NCT02464306Phase 4

Fidaxomicin Versus Standard of Care Therapy in Solid Organ Transplant Recipients With Clostridium Difficile Infection

Withdrawn
NCT02214771

Description of the Use of fidAxomicin in Hospitalized Patients With Documented Clostridium diFficile iNfection and of the managEment of These Patients

Completed
NCT02784002Phase 2

A Study of Ridinilazole (SMT19969) Compared With Fidaxomicin for the Treatment of Clostridium Difficile Infection (CDI)

Completed
NCT01818141Phase 4

Study to Assess Inhibition of Spore Production in Patients With C. Difficile Infections: Fidaxomicin Versus Vancomycin

Completed
NCT00314951Phase 3

Fidaxomicin Versus Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhea (CDAD) (MK-5119-018)

Completed

Drug Details

Intervention Type
DRUG
Total Trials
23