Success Metrics

Clinical Success Rate
94.4%

Based on 118 completed trials

Completion Rate
94%(118/125)
Active Trials
3(2%)
Results Posted
52%(61 trials)
Terminated
7(5%)

Phase Distribution

Ph early_phase_1
1
1%
Ph not_applicable
10
7%
Ph phase_1
13
9%
Ph phase_3
52
36%
Ph phase_2
16
11%
Ph phase_4
43
30%

Phase Distribution

14

Early Stage

16

Mid Stage

95

Late Stage

Phase Distribution135 total trials
Early Phase 1First-in-human
1(0.7%)
Phase 1Safety & dosage
13(9.6%)
Phase 2Efficacy & side effects
16(11.9%)
Phase 3Large-scale testing
52(38.5%)
Phase 4Post-market surveillance
43(31.9%)
N/ANon-phased studies
10(7.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

93.7%

118 of 126 finished

Non-Completion Rate

6.3%

8 ended early

Currently Active

3

trials recruiting

Total Trials

145

all time

Status Distribution
Active(5)
Completed(118)
Terminated(8)
Other(14)

Detailed Status

Completed118
unknown14
Terminated7
Recruiting3
Not yet recruiting2
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
145
Active
3
Success Rate
94.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.7%)
Phase 113 (9.6%)
Phase 216 (11.9%)
Phase 352 (38.5%)
Phase 443 (31.9%)
N/A10 (7.4%)

Trials by Status

withdrawn11%
terminated75%
recruiting32%
not_yet_recruiting21%
completed11881%
unknown1410%

Recent Activity

Clinical Trials (145)

Showing 20 of 145 trialsScroll for more
NCT06686615

A Study of Bempedoic Acid in Combination With Ezetimibe and Either Rosuvastatin or Atorvastatin in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia

Recruiting
NCT07605130Phase 4

Efficacy and Safety Study of Digital Cognitive Training and PCSK9 Inhibitor-Enhanced Lipid-lowering Strategy in Patients With Intracranial Atherosclerotic Stenosis: A 2×2 Randomized Controlled Trial

Not Yet Recruiting
NCT06450366Phase 3

A Study to Evaluate the Efficacy and Safety of Enlicitide (MK-0616, Oral PCSK9 Inhibitor) Compared With Ezetimibe or Bempedoic Acid or Ezetimibe and Bempedoic Acid in Adults With Hypercholesterolemia (MK-0616-018/CORALreef AddOn)

Completed
NCT07474649Phase 3

A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events

Not Yet Recruiting
NCT06437574Phase 2

Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer

Recruiting
NCT07268625Phase 1

Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid / Ezetimibe, and Atorvastatin

Completed
NCT07235189Phase 1

A Study Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid, Ezetimibe, and Atorvastatin

Completed
NCT07201545Phase 1

Evaluating Bioequivalence of a Fixed Dose Combination Versus Tablets of Bempedoic Acid / Ezetimibe and Rosuvastatin

Completed
NCT07182383Phase 1

Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid, Ezetimibe, and Rosuvastatin

Completed
NCT06742853Phase 1

A Study to Investigate the Pharmacokinetics, Safety, Tolerability, and Efficacy of AZD0780 With Ezetimibe Combinations in Healthy Adults With Elevated LDL-C.

Completed
NCT05763875Phase 3

Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy.

Completed
NCT06858332

Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia

Recruiting
NCT00650819Phase 3

Comparison of Ezetimibe Plus Simvastatin Versus Ezetimibe or Simvastatin Alone in Subjects With Primary Hypercholesterolemia (Study P03757)(COMPLETED)

Completed
NCT00651963Phase 4

Open Label Study Evaluating The Use Of Combination Therapy Of Ezetimibe And Statins In Patients With Dyslipidemia In Colombia (0653-141)(COMPLETED)

Completed
NCT00652847Phase 4

Randomized Parallel Group Trial Of The Efficacy And Safety Of Ezetimibe With A Statin Versus Statin Dose Doubling In Patients With Persistent Primary Hypercholesterolemia (0653-152)(COMPLETED)

Completed
NCT00651274Phase 4

Comparison of Co-administration of Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Primary Hypercholesterolemia (P03476)

Completed
NCT00652301Phase 3

A Research Study to Evaluate MK0653 (Ezetimibe) and Simvastatin, Given Together and Alone, on Intestinal Absorption of Cholesterol (0653-050)(COMPLETED)

Completed
NCT00653276Phase 1

MD Ezetimibe Cyclosporine Interaction (0653-057)

Completed
NCT00652717Phase 4

Study To Assess The Efficacy Of A Cholesterol Lowering Drug On Top Of Statins In Patients After Myocardial Infarction (MI)(0653A-150)

Completed
NCT00101439Phase 3

A Study to Evaluate the Effects of Ezetimibe (MK-0653) on the Postprandial (Following a Meal) Lipoprotein Response in Participants With Primary Hypercholesterolemia (High Cholesterol) (MK-0653-072)(COMPLETED)

Completed

Drug Details

Intervention Type
DRUG
Total Trials
145