Success Metrics

Clinical Success Rate
95.5%

Based on 21 completed trials

Completion Rate
95%(21/22)
Active Trials
0(0%)
Results Posted
52%(11 trials)
Terminated
1(4%)

Phase Distribution

Ph phase_1
8
35%
Ph phase_2
4
17%
Ph phase_3
5
22%
Ph phase_4
6
26%

Phase Distribution

8

Early Stage

4

Mid Stage

11

Late Stage

Phase Distribution23 total trials
Phase 1Safety & dosage
8(34.8%)
Phase 2Efficacy & side effects
4(17.4%)
Phase 3Large-scale testing
5(21.7%)
Phase 4Post-market surveillance
6(26.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

95.5%

21 of 22 finished

Non-Completion Rate

4.5%

1 ended early

Currently Active

0

trials recruiting

Total Trials

23

all time

Status Distribution
Completed(21)
Terminated(1)
Other(1)

Detailed Status

Completed21
unknown1
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
23
Active
0
Success Rate
95.5%
Most Advanced
Phase 4

Trials by Phase

Phase 18 (34.8%)
Phase 24 (17.4%)
Phase 35 (21.7%)
Phase 46 (26.1%)

Trials by Status

unknown14%
completed2191%
terminated14%

Recent Activity

Clinical Trials (23)

Showing 20 of 23 trialsScroll for more
NCT01857193Phase 1

Phase Ib Trial of LEE011 With Everolimus (RAD001) and Exemestane in the Treatment of Hormone Receptor Positive HER2 Negative Advanced Breast Cancer

Completed
NCT00426530Phase 1

Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer

Completed
NCT01152801Phase 1

Safety of RAD001 in Chinese Patients With Metastatic Renal Cell Cancer

Completed
NCT00419159Phase 2

Efficacy and Safety of Everolimus in Patients With Metastatic Colorectal Cancer Who Have Failed Prior Targeted Therapy and Chemotherapy

Completed
NCT00968253Phase 1

RAD001 Study in Treatment of Relapsed or Refractory Acute Lymphocytic Leukemia

Completed
NCT01595009Phase 4

An Open-label, Multi-center, Expanded Access Study of Everolimus in Participants With Advanced Neuroendocrine Tumors (NETs) (Core Study) and an Extension Study to the Open-label, Multi-center, Expanded Access Study of Everolimus in Patients With Advanced NETs (E1)

Completed
NCT01548807Phase 1

Phase 1 Trial of the Mammalian Target of Rapamycin (mTOR) Inhibitor Everolimus Plus Radiation Therapy (RT) for Salvage Treatment of Biochemical Recurrence in Prostate Cancer Patients Following Prostatectomy

Completed
NCT01954693Phase 2

A Study of Everolimus in the Treatment of Neurocognitive Problems in Tuberous Sclerosis

Unknown
NCT01514448Phase 4

Safety and Efficacy of Everolimus in Metastatic Renal Cell Carcinoma After Failure of First Line Therapy With Sunitinib or Pazopanib

Completed
NCT00369161Phase 4

A Twelve-month, Multicenter, Open-label, Randomized Study of the Safety, Tolerability and Efficacy of Everolimus With Basiliximab, Corticosteroids and Two Different Exposure Levels of Tacrolimus in de Novo Renal Transplant Recipients

Completed
NCT01626222Phase 3

4EVER - Efficacy, Safety, Health Economics, Translational Research of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer

Completed
NCT00790400Phase 3

Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)

Completed
NCT00170794Phase 3

Renal Safety of Everolimus in Addition to Cyclosporine Microemulsion in Cardiac Transplant Recipients.

Completed
NCT01022996Phase 2

Study of RAD001 in Patients With Relapsed/Refractory Hodgkin Lymphoma That Has Progressed After High-dose Chemotherapy and Autologous Stem Cell Transplant and/or After Gemcitabine- or Vinorelbine- or Vinblastine-based Treatment.

Completed
NCT01365468Phase 2

Efficacy and Safety of RAD001 in Treating Plexiform Neurofibromas (PN) Associated With Neurofibromatosis (NF1)

Terminated
NCT01099527Phase 1

A Trial of RAD001/Capecitabine in Refractory Gastric Cancer

Completed
NCT00788060Phase 1

A Phase Ib Study of Rad001 and Sutent to Treat Renal Cell Carcinoma

Completed
NCT00170846Phase 4

ASCERTAIN: Assessment of Everolimus in Addition to Calcineurin Inhibitor Reduction in the Maintenance of Renal Transplant Recipients

Completed
NCT00792766Phase 1

Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis (TSC) and Sporadic Lymphangioleiomyomatosis (LAM)

Completed
NCT00371826Phase 4

SOCRATES: Steroid or Cyclosporine Removal After Transplantation Using Everolimus

Completed

Drug Details

Intervention Type
DRUG
Total Trials
23