Success Metrics

Clinical Success Rate
90.0%

Based on 9 completed trials

Completion Rate
90%(9/10)
Active Trials
6(35%)
Results Posted
11%(1 trials)
Terminated
1(6%)

Phase Distribution

Ph phase_2
8
47%
Ph phase_1
9
53%

Phase Distribution

9

Early Stage

8

Mid Stage

0

Late Stage

Phase Distribution17 total trials
Phase 1Safety & dosage
9(52.9%)
Phase 2Efficacy & side effects
8(47.1%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

81.8%

9 of 11 finished

Non-Completion Rate

18.2%

2 ended early

Currently Active

6

trials recruiting

Total Trials

17

all time

Status Distribution
Active(6)
Completed(9)
Terminated(2)

Detailed Status

Completed9
Active, not recruiting3
Recruiting3
Terminated1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
17
Active
6
Success Rate
90.0%
Most Advanced
Phase 2

Trials by Phase

Phase 19 (52.9%)
Phase 28 (47.1%)

Trials by Status

active_not_recruiting318%
recruiting318%
terminated16%
completed953%
withdrawn16%

Recent Activity

Clinical Trials (17)

Showing 17 of 17 trials
NCT04791839Phase 2

Safety and Efficacy of Zimberelimab (AB122) in Combination With Domvanalimab (AB154) and Etrumadenant (AB928) in Patients With Previously Treated Non-Small Cell Lung Cancer

Active Not Recruiting
NCT05335941Phase 2

A Phase 2 Study to Evaluate the Triplet Combination of Pemetrexed Plus AB928 (Etrumadenant) + AB122 (Zimberelimab) in Patients With Previously Treated Advanced or Metastatic MTAP Deficient Urothelial Carcinoma

Active Not Recruiting
NCT06048484Phase 2

Combination Therapy in Patients With Localized Pancreatic Ductal Adenocarcinoma

Recruiting
NCT05886634Phase 2

A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma

Active Not Recruiting
NCT04660812Phase 1

An Open Label Study Evaluating the Efficacy and Safety of Etrumadenant (AB928) Based Treatment Combinations in Participants With Metastatic Colorectal Cancer.

Completed
NCT04262856Phase 2

Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer

Completed
NCT04381832Phase 1

Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

Completed
NCT05915442Phase 2

Adenosine Signaling Modulation and Immune Checkpoint Inhibition With Hormone Sensitive Oligometastatic Prostate Cancer

Recruiting
NCT03821246Phase 2

Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy

Recruiting
NCT05177770Phase 2

Study of SRF617 With AB928 (Etrumadenant) and AB122 (Zimberelimab) in Patients With Metastatic Castration Resistant Prostate Cancer

Terminated
NCT03846310Phase 1

A Study to Evaluate Immunotherapy Combinations in Participants With Lung Cancer

Completed
NCT05154136Phase 1

A Drug-Drug Interaction Study to Evaluate the Effect of Itraconazole on the Pharmacokinetic Profile of Etrumadenant in Healthy Adult Participants

Completed
NCT05277012Phase 1

A Study to Evaluate Pharmacokinetics (PK) of Etrumadenant Tablet and Capsule Formulations in Healthy Adult Participants

Completed
NCT03719326Phase 1

A Study to Evaluate Safety/Tolerability of Immunotherapy Combinations in Participants With Triple-Negative Breast Cancer or Gynecologic Malignancies

Completed
NCT03720678Phase 1

A Study to Evaluate Immunotherapy Combinations in Participants With Gastrointestinal Malignancies

Completed
NCT03629756Phase 1

A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies

Completed
NCT04892875Phase 1

A Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor / Adenosine 2b Receptor Inhibitor AB928 Therapies in Locally Advanced Head and Neck Cancers

Withdrawn

All 17 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
17