Success Metrics

Clinical Success Rate
72.7%

Based on 8 completed trials

Completion Rate
73%(8/11)
Active Trials
0(0%)
Results Posted
100%(8 trials)
Terminated
3(27%)

Phase Distribution

Ph phase_3
7
64%
Ph phase_1
3
27%
Ph phase_2
1
9%

Phase Distribution

3

Early Stage

1

Mid Stage

7

Late Stage

Phase Distribution11 total trials
Phase 1Safety & dosage
3(27.3%)
Phase 2Efficacy & side effects
1(9.1%)
Phase 3Large-scale testing
7(63.6%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

72.7%

8 of 11 finished

Non-Completion Rate

27.3%

3 ended early

Currently Active

0

trials recruiting

Total Trials

11

all time

Status Distribution
Completed(8)
Terminated(3)

Detailed Status

Completed8
Terminated3

Development Timeline

Analytics

Development Status

Total Trials
11
Active
0
Success Rate
72.7%
Most Advanced
Phase 3

Trials by Phase

Phase 13 (27.3%)
Phase 21 (9.1%)
Phase 37 (63.6%)

Trials by Status

terminated327%
completed873%

Recent Activity

Clinical Trials (11)

Showing 11 of 11 trials
NCT03478956Phase 1

A Phase I Study of Etrolizumab Followed by Open-Label Extension and Safety Monitoring in Pediatric Patients With Moderate to Severe Ulcerative Colitis or Moderate to Severe Crohn's Disease

Terminated
NCT02403323Phase 3

Open-Label Extension and Safety Study for Participants With Crohn's Disease Previously Enrolled in the Etrolizumab Phase III Study GA29144

Terminated
NCT02118584Phase 3

Study for Participants With Ulcerative Colitis Previously Enrolled in Etrolizumab Phase II/III Studies

Terminated
NCT02394028Phase 3

A Study to Assess Whether Etrolizumab is a Safe and Efficacious Treatment for Participants With Moderately to Severely Active Crohn's Disease

Completed
NCT02136069Phase 3

A Study Comparing the Efficacy and Safety of Etrolizumab to Infliximab in Participants With Moderate to Severe Ulcerative Colitis Who Are Naïve to Tumor Necrosis Factor (TNF) Inhibitors

Completed
NCT02165215Phase 3

A Study of the Efficacy and Safety of Etrolizumab Treatment in Maintenance of Disease Remission in Ulcerative Colitis (UC) Participants Who Are Naive to Tumor Necrosis Factor (TNF) Inhibitors

Completed
NCT02163759Phase 3

A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) Inhibitors

Completed
NCT02171429Phase 3

A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) Inhibitors

Completed
NCT01461317Phase 2

Study to Evaluate the Long-term Safety of Etrolizumab in Participants With Moderate to Severe Ulcerative Colitis

Completed
NCT02996019Phase 1

A Study to Compare Pharmacokinetics (PK) of Etrolizumab Administered Subcutaneously by a Prefilled Syringe With Needle Safety Device (PFS-NSD) or an Auto-injector (AI)

Completed
NCT02629744Phase 1

A Study to Evaluate Pain, Tolerability, Safety, and Usability of a Single Self-administered Etrolizumab by Auto-injector in Healthy Participants

Completed

All 11 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
11