Success Metrics

Clinical Success Rate
98.3%

Based on 58 completed trials

Completion Rate
98%(58/59)
Active Trials
31(27%)
Results Posted
16%(9 trials)
Terminated
1(1%)

Phase Distribution

Ph early_phase_1
4
3%
Ph phase_4
31
27%
Ph phase_3
10
9%
Ph not_applicable
39
34%
Ph phase_1
20
17%
Ph phase_2
9
8%

Phase Distribution

24

Early Stage

9

Mid Stage

41

Late Stage

Phase Distribution113 total trials
Early Phase 1First-in-human
4(3.5%)
Phase 1Safety & dosage
20(17.7%)
Phase 2Efficacy & side effects
9(8.0%)
Phase 3Large-scale testing
10(8.8%)
Phase 4Post-market surveillance
31(27.4%)
N/ANon-phased studies
39(34.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

93.5%

58 of 62 finished

Non-Completion Rate

6.5%

4 ended early

Currently Active

31

trials recruiting

Total Trials

116

all time

Status Distribution
Active(37)
Completed(58)
Terminated(4)
Other(17)

Detailed Status

Completed58
Recruiting26
unknown17
Not yet recruiting6
Active, not recruiting5
Withdrawn3

Development Timeline

Analytics

Development Status

Total Trials
116
Active
31
Success Rate
98.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (3.5%)
Phase 120 (17.7%)
Phase 29 (8.0%)
Phase 310 (8.8%)
Phase 431 (27.4%)
N/A39 (34.5%)

Trials by Status

withdrawn33%
terminated11%
active_not_recruiting54%
completed5850%
unknown1715%
not_yet_recruiting65%
recruiting2622%

Recent Activity

Clinical Trials (116)

Showing 20 of 116 trialsScroll for more
NCT07227454Phase 3

A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

Recruiting
NCT07308756Phase 4

Impact of Perioperative Dexmedetomidine and Esketamine on Postoperative Quality of Recovery

Recruiting
NCT06062550Phase 4

Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia After Scoliosis Correction Surgery

Active Not Recruiting
NCT07315074Not Applicable

Effect of Esketamine on Postoperative Sleep in Postmenopausal Women

Not Yet Recruiting
NCT04480918

University of Iowa Interventional Psychiatry Service Patient Registry

Recruiting
NCT06624878Not Applicable

Esketamine for Prevention of Depression After Cytoreductive Surgery in Ovarian Cancer

Completed
NCT06559280Early Phase 1

The Effect of Subclinical Dose of Ketamine on Early Postoperative Pain Sensitivity in Patients Undergoing Salpingectomy

Completed
NCT07374458Not Applicable

Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery

Not Yet Recruiting
NCT06310785Not Applicable

Esketamine Anesthesia in Thoracic Surgery

Completed
NCT03756961Not Applicable

Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity Surgery

Recruiting
NCT07317206Phase 2

Ayahuasca, Esketamine and PTSD

Recruiting
NCT07317232Not Applicable

Ayahuasca, Esketamine and Premenstrual Symptoms

Recruiting
NCT07317219Not Applicable

Ayahuasca, Esketamine and Body Image Perception

Recruiting
NCT07212946Phase 2

Ayahuasca and Esketamine for Major Depression

Completed
NCT05450432Phase 4

Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression

Recruiting
NCT06853431Phase 4

Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine Combined With Esketamine for Preoperative Sedation in Pediatric General Anesthesia

Recruiting
NCT06284668Not Applicable

Esketamine vs Remimazolam for Postoperative Sleep Disturbance and Anxiety

Completed
NCT06608030Not Applicable

Effect of Esketamine on Perioperative Negative Mood in Patients Undergoing Cardiac Valve Surgery

Completed
NCT05092152Phase 2

Propofol Versus Ketamine for Rapid Sequence Intubation in Critically Ill Patients

Completed
NCT06431386Not Applicable

Behavioural Activation Therapy and Esketamine for Resistant Depression

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
116