Success Metrics

Clinical Success Rate
98.3%

Based on 59 completed trials

Completion Rate
98%(59/60)
Active Trials
32(26%)
Results Posted
15%(9 trials)
Terminated
1(1%)

Phase Distribution

Ph phase_3
10
8%
Ph phase_1
20
17%
Ph phase_4
34
28%
Ph not_applicable
41
34%
Ph early_phase_1
4
3%
Ph phase_2
9
7%

Phase Distribution

24

Early Stage

9

Mid Stage

44

Late Stage

Phase Distribution118 total trials
Early Phase 1First-in-human
4(3.4%)
Phase 1Safety & dosage
20(16.9%)
Phase 2Efficacy & side effects
9(7.6%)
Phase 3Large-scale testing
10(8.5%)
Phase 4Post-market surveillance
34(28.8%)
N/ANon-phased studies
41(34.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

93.7%

59 of 63 finished

Non-Completion Rate

6.3%

4 ended early

Currently Active

32

trials recruiting

Total Trials

121

all time

Status Distribution
Active(41)
Completed(59)
Terminated(4)
Other(17)

Detailed Status

Completed59
Recruiting25
unknown17
Not yet recruiting9
Active, not recruiting7
Withdrawn3

Development Timeline

Analytics

Development Status

Total Trials
121
Active
32
Success Rate
98.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (3.4%)
Phase 120 (16.9%)
Phase 29 (7.6%)
Phase 310 (8.5%)
Phase 434 (28.8%)
N/A41 (34.7%)

Trials by Status

withdrawn32%
not_yet_recruiting97%
active_not_recruiting76%
recruiting2521%
completed5949%
terminated11%
unknown1714%

Recent Activity

Clinical Trials (121)

Showing 20 of 121 trialsScroll for more
NCT07644663Phase 4

The Effects of Different Anesthetics on the Brain's Neural Networks

Not Yet Recruiting
NCT07227454Phase 3

A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

Recruiting
NCT07625826Not Applicable

The Effect of Esketamine on Cough Reflex During Tracheal Extubation in Patients Undergoing Open Thyroid Surgery

Not Yet Recruiting
NCT07597486Not Applicable

The Effect of Intraoperative Esketamine Infusion on Pruritus in Elderly Surgical Patients

Not Yet Recruiting
NCT06853041Phase 4

ESKetamine Low-dose vs Ketamine Low-dose for Severe Acute Pain in Emergency Units, Comparison of PsychodyslEptic Effects

Completed
NCT07179913Phase 4

The Improvement of Low-dose Esketamine on Postoperative Depression in Patients Undergoing Bariatric Surgery With Preoperative Depression

Active Not Recruiting
NCT07570160Phase 4

Intranasal Dexmedetomidine or Esketamine for Negative Postoperative Behavioral Changes in Children

Not Yet Recruiting
NCT07556172Phase 4

Clinical Study of Esketamine in Patients With Sepsis Undergoing Invasive Mechanical Ventilation

Active Not Recruiting
NCT06784388Early Phase 1

Personalized DBS Targeting for Treating Depression

Recruiting
NCT05092152Phase 2

Propofol Versus Ketamine for Rapid Sequence Intubation in Critically Ill Patients

Completed
NCT06062550Phase 4

Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia After Scoliosis Correction Surgery

Active Not Recruiting
NCT07308756Phase 4

Impact of Perioperative Dexmedetomidine and Esketamine on Postoperative Quality of Recovery

Recruiting
NCT07315074Not Applicable

Effect of Esketamine on Postoperative Sleep in Postmenopausal Women

Not Yet Recruiting
NCT04480918

University of Iowa Interventional Psychiatry Service Patient Registry

Recruiting
NCT06624878Not Applicable

Esketamine for Prevention of Depression After Cytoreductive Surgery in Ovarian Cancer

Completed
NCT06559280Early Phase 1

The Effect of Subclinical Dose of Ketamine on Early Postoperative Pain Sensitivity in Patients Undergoing Salpingectomy

Completed
NCT07374458Not Applicable

Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery

Not Yet Recruiting
NCT06310785Not Applicable

Esketamine Anesthesia in Thoracic Surgery

Completed
NCT03756961Not Applicable

Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity Surgery

Recruiting
NCT07317219Not Applicable

Ayahuasca, Esketamine and Body Image Perception

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
121