Success Metrics

Clinical Success Rate
80.0%

Based on 48 completed trials

Completion Rate
80%(48/60)
Active Trials
7(8%)
Results Posted
44%(21 trials)
Terminated
12(14%)

Phase Distribution

Ph phase_2
18
22%
Ph early_phase_1
3
4%
Ph phase_3
12
14%
Ph phase_4
29
35%
Ph phase_1
6
7%
Ph not_applicable
12
14%

Phase Distribution

9

Early Stage

18

Mid Stage

41

Late Stage

Phase Distribution80 total trials
Early Phase 1First-in-human
3(3.8%)
Phase 1Safety & dosage
6(7.5%)
Phase 2Efficacy & side effects
18(22.5%)
Phase 3Large-scale testing
12(15.0%)
Phase 4Post-market surveillance
29(36.3%)
N/ANon-phased studies
12(15.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.8%

48 of 65 finished

Non-Completion Rate

26.2%

17 ended early

Currently Active

7

trials recruiting

Total Trials

83

all time

Status Distribution
Active(9)
Completed(48)
Terminated(17)
Other(9)

Detailed Status

Completed48
Terminated12
unknown9
Withdrawn5
Recruiting4
Active, not recruiting3

Development Timeline

Analytics

Development Status

Total Trials
83
Active
7
Success Rate
80.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (3.8%)
Phase 16 (7.5%)
Phase 218 (22.5%)
Phase 312 (15.0%)
Phase 429 (36.3%)
N/A12 (15.0%)

Trials by Status

unknown911%
enrolling_by_invitation11%
terminated1214%
completed4858%
active_not_recruiting34%
not_yet_recruiting11%
recruiting45%
withdrawn56%

Recent Activity

Clinical Trials (83)

Showing 20 of 83 trialsScroll for more
NCT04840342Phase 4

MR Antagonist and LSD1

Active Not Recruiting
NCT07029503Phase 2

Swedish Cardiac And Renal Failure Study-1

Recruiting
NCT06749418Early Phase 1

Vascular Effects of High-Salt After Preeclampsia

Recruiting
NCT07345845Early Phase 1

MR and Inflammation After Preeclampsia

Active Not Recruiting
NCT05593055Phase 4

Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

Recruiting
NCT01794091Phase 4

Detection of Diffuse Scar in Patients With Diabetes

Withdrawn
NCT04519164Phase 4

Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in Obesity

Completed
NCT06649409Phase 1

Evaluation of Vamorolone Mineralocorticoid Receptor Antagonism in Healthy Subjects

Completed
NCT05030545Phase 4

Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

Recruiting
NCT03165240Phase 1

This International Study Tests BI 690517 in Patients With Diabetic Kidney Disease. The Study Tests How 3 Different Doses of BI 690517 Are Taken up in the Body and How Well They Are Tolerated

Completed
NCT06168994Phase 4

Role of Eplerenone in Reducing Recurrence of Atrial Fibrillation in Patient With Structural Heart Disease

Not Yet Recruiting
NCT03342690

Drug Use Investigation of Selara Tablets (an Investigation for Chronic Heart Failure)

Completed
NCT02490904Phase 3

Eplerenone in Patients Undergoing REnal Transplant (EPURE TRANSPLANT)

Active Not Recruiting
NCT02740179Not Applicable

Effects of Eplerenone on Cardiovascular Disease in HIV (MIRACLE HIV Study)

Completed
NCT02525796Phase 2

Evaluating Alternative Medical Therapies in Primary Hyperparathyroidism

Completed
NCT03984591Phase 4

A Registry-based Cluster Randomized Trial to Compare the Effect of Spironolactone vs. Eplerenone on Clinical Outcomes in Patients With Symptomatic Systolic Heart Failure

Enrolling By Invitation
NCT01586442Phase 3

Comparison of Eplerenone Versus Spironolactone in Heart Failure Patients With Glucose Intolerance or Type 2 Diabetes

Completed
NCT01996449Phase 2

The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension

Completed
NCT05104138

Eplerenone Versus PDT: Comparative Study by OCTA

Completed
NCT01857856Phase 3

PHOspholamban RElated CArdiomyopathy STudy - Intervention

Completed

Drug Details

Intervention Type
DRUG
Total Trials
83