Success Metrics

Clinical Success Rate
91.2%

Based on 31 completed trials

Completion Rate
91%(31/34)
Active Trials
0(0%)
Results Posted
100%(31 trials)
Terminated
3(9%)

Phase Distribution

Ph phase_3
3
9%
Ph phase_1
5
14%
Ph phase_2
27
77%

Phase Distribution

5

Early Stage

27

Mid Stage

3

Late Stage

Phase Distribution35 total trials
Phase 1Safety & dosage
5(14.3%)
Phase 2Efficacy & side effects
27(77.1%)
Phase 3Large-scale testing
3(8.6%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

91.2%

31 of 34 finished

Non-Completion Rate

8.8%

3 ended early

Currently Active

0

trials recruiting

Total Trials

35

all time

Status Distribution
Completed(31)
Terminated(3)
Other(1)

Detailed Status

Completed31
Terminated3
Suspended1

Development Timeline

Analytics

Development Status

Total Trials
35
Active
0
Success Rate
91.2%
Most Advanced
Phase 3

Trials by Phase

Phase 15 (14.3%)
Phase 227 (77.1%)
Phase 33 (8.6%)

Trials by Status

terminated39%
suspended13%
completed3189%

Recent Activity

Clinical Trials (35)

Showing 20 of 35 trialsScroll for more
NCT05463679Phase 3

Investigate Efficacy, Safety, and Pharmacokinetics of Enzastaurin for the Prevention of Arterial Events in Patients With Vascular Ehlers-Danlos Syndrome.

Suspended
NCT00308750Phase 2

First Line Chemotherapy Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)

Completed
NCT00533429Phase 2

Study of Pemetrexed + Carboplatin + Bevacizumab + Enzastaurin Versus Pemetrexed + Carboplatin + Bevacizumab + Placebo in Participants With Non-Small Cell Lung Cancer Who Have Not Been Previously Treated With Chemotherapy

Completed
NCT00452413Phase 1

A Study of Enzastaurin and Erlotinib in Participants With Solid Tumors and Lung Cancer

Completed
NCT00420381Phase 2

Evaluation of Enzastaurin in the Treatment of Persistent or Recurrent Ovarian or Primary Peritoneal Cancer

Completed
NCT00428714Phase 2

Phase 2 Trial of Enzastaurin in Prostate Cancer in Participants Who Have Had Hormonal and Chemotherapy

Completed
NCT00466440Phase 2

A Phase 2 Study With Enzastaurin Plus Chemotherapy or Placebo Plus Chemotherapy for Prostate Cancer Patients

Completed
NCT00538681Phase 2

Study for Participants With Advanced, Not Amenable to Surgery, or Metastatic Lung Cancer Comparing Treatment With Pemetrexed + Cisplatin + Enzastaurin Versus Pemetrexed + Cisplatin + Placebo

Terminated
NCT00415363Phase 2

Study of Enzastaurin Versus Placebo in the Treatment of Patients With Brain Metastases of Lung Cancer, After Whole Brain Radiation Therapy

Completed
NCT00391118Phase 2

Comparing Two Treatments for Ovarian Cancer: Standard Chemotherapy Plus Enzastaurin, or Placebo ("Sugar Pill")

Completed
NCT00542919Phase 2

A Study for Patients With Non-Hodgkin's Lymphomas

Completed
NCT00744991Phase 2

A Study for Participants With Relapsed Cutaneous T-Cell Lymphoma

Completed
NCT01432951Phase 1

A Study of Enzastaurin in Chinese Patients With Advanced and/or Metastatic Solid Tumors or Lymphoma

Completed
NCT00536939Phase 2

Trial of Paclitaxel, Bevacizumab, and Enzastaurin Versus Paclitaxel, Bevacizumab and Placebo for Breast Cancer

Terminated
NCT00586508Phase 2

Trial of Enzastaurin and Bevacizumab in Participants With Recurrent Malignant Gliomas

Completed
NCT00414960Phase 2

A Trial of Placebo Versus Enzastaurin for Lung Cancer Prevention in Former Smokers

Completed
NCT00718419Phase 2

A Study for Patients That Have Been Previously Been Treated in Waldenstrom's Macroglobulinemia or Multiple Myeloma

Completed
NCT00267020Phase 2

Phase 2 Study of Gemcitabine or Gemcitabine + Enzastaurin in Participants With Advanced or Metastatic Pancreatic Cancer

Completed
NCT00437294Phase 2

Enzastaurin in Combination of Capecitabine to Treat Breast Cancer

Terminated
NCT00402116Phase 1

Phase 1/2 Study of Enzastaurin in Newly Diagnosed Glioblastoma Multiforme (GBM) and Gliosarcoma (GS) Patients

Completed

Drug Details

Intervention Type
DRUG
Total Trials
35