Success Metrics

Clinical Success Rate
78.7%

Based on 133 completed trials

Completion Rate
79%(133/169)
Active Trials
85(31%)
Results Posted
80%(107 trials)
Terminated
36(13%)

Phase Distribution

Ph phase_4
10
4%
Ph phase_2
122
44%
Ph phase_3
41
15%
Ph phase_1
78
28%
Ph early_phase_1
1
0%
Ph not_applicable
2
1%

Phase Distribution

79

Early Stage

122

Mid Stage

51

Late Stage

Phase Distribution254 total trials
Early Phase 1First-in-human
1(0.4%)
Phase 1Safety & dosage
78(30.7%)
Phase 2Efficacy & side effects
122(48.0%)
Phase 3Large-scale testing
41(16.1%)
Phase 4Post-market surveillance
10(3.9%)
N/ANon-phased studies
2(0.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.0%

133 of 175 finished

Non-Completion Rate

24.0%

42 ended early

Currently Active

85

trials recruiting

Total Trials

276

all time

Status Distribution
Active(93)
Completed(133)
Terminated(42)
Other(8)

Detailed Status

Completed133
Recruiting49
Active, not recruiting36
Terminated36
unknown8
Not yet recruiting7

Development Timeline

Analytics

Development Status

Total Trials
276
Active
85
Success Rate
78.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.4%)
Phase 178 (30.7%)
Phase 2122 (48.0%)
Phase 341 (16.1%)
Phase 410 (3.9%)
N/A2 (0.8%)

Trials by Status

unknown83%
recruiting4918%
enrolling_by_invitation10%
not_yet_recruiting73%
withdrawn62%
active_not_recruiting3613%
terminated3613%
completed13348%

Recent Activity

Clinical Trials (276)

Showing 20 of 276 trialsScroll for more
NCT02960022Phase 2

A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study

Recruiting
NCT05901649

A Study for the Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With Androgen Deprivation Therapy (ADT) Plus Apalutamide or Enzalutamide

Completed
NCT06863272Phase 1

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

Recruiting
NCT07028853Phase 3

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Recruiting
NCT06629779Phase 3

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

Recruiting
NCT06120491Phase 3

Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents

Active Not Recruiting
NCT03899155Phase 2

Pan Tumor Rollover Study

Recruiting
NCT03460977Phase 1

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

Recruiting
NCT03768063Phase 3

A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study

Active Not Recruiting
NCT06096870Phase 2

Enzalutamide and PDS01ADC in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy

Recruiting
NCT04076059Phase 3

An Efficacy and Safety Study of Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus ADT in Chinese Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)

Active Not Recruiting
NCT06136624Phase 3

Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

Recruiting
NCT04471974Phase 2

ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer

Active Not Recruiting
NCT07723248Phase 3

A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1)

Recruiting
NCT06136650Phase 3

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Recruiting
NCT06764485Phase 3

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

Recruiting
NCT06520345Phase 3

The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT Global)

Recruiting
NCT06378866Phase 2

Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial

Recruiting
NCT04363164Phase 2

Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression

Recruiting
NCT07711002Phase 3

Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05)

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
276