Success Metrics

Clinical Success Rate
77.4%

Based on 130 completed trials

Completion Rate
77%(130/168)
Active Trials
87(31%)
Results Posted
85%(111 trials)
Terminated
38(14%)

Phase Distribution

Ph phase_1
79
28%
Ph phase_4
10
4%
Ph phase_2
123
44%
Ph not_applicable
2
1%
Ph phase_3
43
15%
Ph early_phase_1
1
0%

Phase Distribution

80

Early Stage

123

Mid Stage

53

Late Stage

Phase Distribution258 total trials
Early Phase 1First-in-human
1(0.4%)
Phase 1Safety & dosage
79(30.6%)
Phase 2Efficacy & side effects
123(47.7%)
Phase 3Large-scale testing
43(16.7%)
Phase 4Post-market surveillance
10(3.9%)
N/ANon-phased studies
2(0.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.7%

130 of 174 finished

Non-Completion Rate

25.3%

44 ended early

Currently Active

87

trials recruiting

Total Trials

280

all time

Status Distribution
Active(98)
Completed(130)
Terminated(44)
Other(8)

Detailed Status

Completed130
Recruiting47
Active, not recruiting40
Terminated38
Not yet recruiting9
unknown8

Development Timeline

Analytics

Development Status

Total Trials
280
Active
87
Success Rate
77.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.4%)
Phase 179 (30.6%)
Phase 2123 (47.7%)
Phase 343 (16.7%)
Phase 410 (3.9%)
N/A2 (0.8%)

Trials by Status

withdrawn62%
not_yet_recruiting93%
completed13046%
recruiting4717%
unknown83%
enrolling_by_invitation21%
terminated3814%
active_not_recruiting4014%

Recent Activity

Clinical Trials (280)

Showing 20 of 280 trialsScroll for more
NCT06632977Phase 2

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

Recruiting
NCT03460977Phase 1

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

Recruiting
NCT07802704Phase 3

A Study of Risvutatug Rezetecan in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) [EMBOLD Prostate-302]

Recruiting
NCT07226986Phase 1

A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC

Recruiting
NCT07852195Phase 2

Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer

Not Yet Recruiting
NCT06764485Phase 3

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

Active Not Recruiting
NCT05112965Phase 3

An Extension Study in Participants Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study (IMbrella C)

Active Not Recruiting
NCT05081193Phase 2

Safety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy for Men With Metastatic Castrate Resistant Prostate Cancer

Active Not Recruiting
NCT04191096Phase 3

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)

Terminated
NCT03834493Phase 3

Study of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-641/KEYNOTE-641)

Terminated
NCT05818683Phase 1

A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

Recruiting
NCT06136650Phase 3

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Recruiting
NCT07277270Phase 1

A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors

Recruiting
NCT06629779Phase 3

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

Recruiting
NCT03568656Phase 1

Study to Evaluate CCS1477 in Advanced Tumours

Completed
NCT07028853Phase 3

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Recruiting
NCT03899155Phase 2

Pan Tumor Rollover Study

Recruiting
NCT07570979Phase 1

A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer

Recruiting
NCT04335682Phase 2

Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide

Completed
NCT06991556Phase 2

An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
280