Success Metrics

Clinical Success Rate
78.7%

Based on 129 completed trials

Completion Rate
79%(129/164)
Active Trials
87(32%)
Results Posted
81%(105 trials)
Terminated
35(13%)

Phase Distribution

Ph early_phase_1
1
0%
Ph phase_1
78
29%
Ph phase_2
122
45%
Ph phase_4
10
4%
Ph not_applicable
2
1%
Ph phase_3
37
14%

Phase Distribution

79

Early Stage

122

Mid Stage

47

Late Stage

Phase Distribution250 total trials
Early Phase 1First-in-human
1(0.4%)
Phase 1Safety & dosage
78(31.2%)
Phase 2Efficacy & side effects
122(48.8%)
Phase 3Large-scale testing
37(14.8%)
Phase 4Post-market surveillance
10(4.0%)
N/ANon-phased studies
2(0.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.9%

129 of 170 finished

Non-Completion Rate

24.1%

41 ended early

Currently Active

87

trials recruiting

Total Trials

272

all time

Status Distribution
Active(94)
Completed(129)
Terminated(41)
Other(8)

Detailed Status

Completed129
Recruiting50
Active, not recruiting37
Terminated35
unknown8
Not yet recruiting6

Development Timeline

Analytics

Development Status

Total Trials
272
Active
87
Success Rate
78.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.4%)
Phase 178 (31.2%)
Phase 2122 (48.8%)
Phase 337 (14.8%)
Phase 410 (4.0%)
N/A2 (0.8%)

Trials by Status

enrolling_by_invitation10%
completed12947%
not_yet_recruiting62%
terminated3513%
withdrawn62%
recruiting5018%
active_not_recruiting3714%
unknown83%

Recent Activity

Clinical Trials (272)

Showing 20 of 272 trialsScroll for more
NCT07287150Phase 2

A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer

Recruiting
NCT03123978Phase 1

Enzalutamide and Niclosamide in Treating Patients With Recurrent or Metastatic Castration-Resistant Prostate Cancer

Completed
NCT02446444Phase 3

Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer

Active Not Recruiting
NCT07570979Phase 1

A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer

Recruiting
NCT06764485Phase 3

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

Recruiting
NCT06136624Phase 3

Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

Recruiting
NCT06629779Phase 3

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

Recruiting
NCT03460977Phase 1

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

Recruiting
NCT06863272Phase 1

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

Recruiting
NCT05873192Phase 2

Presurgical Phase II Study of Talazoparib in Combination With Enzalutamide in Prostate Cancer

Recruiting
NCT06136650Phase 3

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Recruiting
NCT06551324Phase 3

A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).

Active Not Recruiting
NCT06616155Phase 1

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

Recruiting
NCT07028853Phase 3

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Recruiting
NCT06520345Phase 3

The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT Global)

Recruiting
NCT07226986Phase 1

A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC

Recruiting
NCT06991556Phase 2

An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Recruiting
NCT04191096Phase 3

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)

Completed
NCT03860987Phase 2

Neoadjuvant Androgen Deprivation Therapy Combined With Enzalutamide and Abiraterone Using Multiparametric MRI and 18FDCFPyL PET/CT in Newly Diagnosed Prostate Cancer

Active Not Recruiting
NCT03768063Phase 3

A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
272