Success Metrics

Clinical Success Rate
86.7%

Based on 13 completed trials

Completion Rate
87%(13/15)
Active Trials
23(44%)
Results Posted
31%(4 trials)
Terminated
2(4%)

Phase Distribution

Ph phase_4
1
2%
Ph phase_1
4
8%
Ph phase_2
21
40%
Ph not_applicable
5
10%
Ph phase_3
13
25%

Phase Distribution

4

Early Stage

21

Mid Stage

14

Late Stage

Phase Distribution44 total trials
Phase 1Safety & dosage
4(9.1%)
Phase 2Efficacy & side effects
21(47.7%)
Phase 3Large-scale testing
13(29.5%)
Phase 4Post-market surveillance
1(2.3%)
N/ANon-phased studies
5(11.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

72.2%

13 of 18 finished

Non-Completion Rate

27.8%

5 ended early

Currently Active

23

trials recruiting

Total Trials

52

all time

Status Distribution
Active(28)
Completed(13)
Terminated(5)
Other(6)

Detailed Status

Recruiting17
Completed13
Active, not recruiting6
unknown6
Not yet recruiting5
Withdrawn3

Development Timeline

Analytics

Development Status

Total Trials
52
Active
23
Success Rate
86.7%
Most Advanced
Phase 4

Trials by Phase

Phase 14 (9.1%)
Phase 221 (47.7%)
Phase 313 (29.5%)
Phase 41 (2.3%)
N/A5 (11.4%)

Trials by Status

recruiting1733%
terminated24%
active_not_recruiting612%
completed1325%
not_yet_recruiting510%
unknown612%
withdrawn36%

Recent Activity

Clinical Trials (52)

Showing 20 of 52 trialsScroll for more
NCT06369285Phase 2

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

Recruiting
NCT06637150Phase 3

Dalpicilib-Enhanced vs. Standard Endocrine Therapy in ER+ HER2- Early Breast Cancer

Recruiting
NCT04923542Phase 1

SRS & Abemaciclib w/wo Imlunestrant in the Management of HR+/HER2- Breast CA Brain Metastases

Recruiting
NCT07844759Not Applicable

SOLIS: Single-Dose Radiotherapy With Omission of Lumpectomy for Intact Small Breast Cancers

Not Yet Recruiting
NCT03573648Phase 2

Neoadjuvant Endocrine Therapy, Palbociclib, Avelumab in Estrogen Receptor Positive Breast Cancer

Active Not Recruiting
NCT05306041Phase 2

Neoadjuvant Endocrine Therapy +/- the PI3K Inhibitor Inavolisib in HER2+, HR+, PIK3CA Mutant Early Breast Cancer

Recruiting
NCT07613151

Negative/Low Hormone Receptor And/or HER2 POsitive Lobular Invasive Breast Carcinoma - A Real-World International Cohort Study

Recruiting
NCT05919108Phase 2

Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers

Recruiting
NCT06914440Phase 2

Neoadjuvant SBRT Followed by Nab-Paclitaxel Combined With Toripalimab in HR+/HER2- Breast Cancer

Recruiting
NCT07745257Phase 2

Culmerciclib Plus Anlotinib and Endocrine Therapy for HR-Positive/HER2-Negative Metastatic Breast Cancer With Brain Metastases

Not Yet Recruiting
NCT07683754Phase 3

T-DXd Based Therapy Followed by Endocrine Therapy Plus Dual HER2 Blockade in First-line HER2+/ HR+ Metastatic Breast Cancer and Retreatment With T-DXd

Not Yet Recruiting
NCT07708194Phase 1

Entinostat Plus Pyrotinib and Endocrine Therapy in Advanced Triple-Positive Breast Cancer After Trastuzumab Failure

Recruiting
NCT02764541Phase 2

Palbociclib and Endocrine Therapy for LObular Breast Cancer Preoperative Study (PELOPS)

Active Not Recruiting
NCT04921137Phase 4

Evaluating Harms and Benefits of Endocrine Therapy in Patients ≥70 Years of Age With Lower Risk Breast Cancer

Recruiting
NCT06195709Phase 3

ECLECTIC: EstroTEP and Circulating Biomarkers for ER-positive HER2-negative Metastatic Breast Cancer Patients

Recruiting
NCT05399329

Study to Evaluate Real-world Effectiveness With Palbociclib Plus Endocrine Therapy as First-line/Second-line Treatment for HR+/HER2- Advanced Breast Cancer in Japan

Completed
NCT02057133Phase 1

A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread

Active Not Recruiting
NCT03285412Phase 2

CDK 4/6 Inhibitor, Ribociclib, With Adjuvant Endocrine Therapy for ER-positive Breast Cancer

Active Not Recruiting
NCT02352883Not Applicable

MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ

Active Not Recruiting
NCT03725059Phase 3

Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
52