Success Metrics

Active Trials
6(67%)

Phase Distribution

Ph phase_1
6
67%
Ph phase_2
3
33%

Phase Distribution

6

Early Stage

3

Mid Stage

0

Late Stage

Phase Distribution9 total trials
Phase 1Safety & dosage
6(66.7%)
Phase 2Efficacy & side effects
3(33.3%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

0.0%

0 of 0 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

6

trials recruiting

Total Trials

9

all time

Status Distribution
Active(8)
Other(1)

Detailed Status

Recruiting6
Not yet recruiting2
Suspended1

Development Timeline

Analytics

Development Status

Total Trials
9
Active
6
Success Rate
N/A
Most Advanced
Phase 2

Trials by Phase

Phase 16 (66.7%)
Phase 23 (33.3%)

Trials by Status

not_yet_recruiting222%
recruiting667%
suspended111%

Recent Activity

Clinical Trials (9)

Showing 9 of 9 trials
NCT03328078Phase 1

CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT07463820Phase 2

A Trial Comparing Three Different Treatment Options for Adults With Low-Risk Myelodysplasia and Anemia (A MyeloMATCH Treatment Trial)

Not Yet Recruiting
NCT06696768Phase 1

Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer

Recruiting
NCT05685602Phase 1

CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer

Recruiting
NCT06439836Phase 1

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

Recruiting
NCT07271667Phase 2

A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

Recruiting
NCT07107750Phase 1

Emavusertib (CA-4948) in Combination With Cisplatin, Gemcitabine, and Durvalumab in Patients With Untreated Advanced or Metastatic Biliary Tract Cancer

Not Yet Recruiting
NCT04278768Phase 1

Dose Escalation/ Expansion Study of CA-4948 as Monotherapy in Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Suspended

All 9 trials loaded

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
9