Success Metrics

Clinical Success Rate
65.0%

Based on 13 completed trials

Completion Rate
65%(13/20)
Active Trials
9(23%)
Results Posted
115%(15 trials)
Terminated
7(18%)

Phase Distribution

Ph phase_2
15
38%
Ph early_phase_1
1
3%
Ph phase_1
18
45%
Ph phase_3
4
10%

Phase Distribution

19

Early Stage

15

Mid Stage

4

Late Stage

Phase Distribution38 total trials
Early Phase 1First-in-human
1(2.6%)
Phase 1Safety & dosage
18(47.4%)
Phase 2Efficacy & side effects
15(39.5%)
Phase 3Large-scale testing
4(10.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

13 of 26 finished

Non-Completion Rate

50.0%

13 ended early

Currently Active

9

trials recruiting

Total Trials

40

all time

Status Distribution
Active(11)
Completed(13)
Terminated(13)
Other(3)

Detailed Status

Completed13
Terminated7
Withdrawn6
Recruiting5
Active, not recruiting4
Not yet recruiting2

Development Timeline

Analytics

Development Status

Total Trials
40
Active
9
Success Rate
65.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (2.6%)
Phase 118 (47.4%)
Phase 215 (39.5%)
Phase 34 (10.5%)

Trials by Status

not_yet_recruiting25%
suspended13%
terminated718%
withdrawn615%
active_not_recruiting410%
recruiting513%
unknown25%
completed1333%

Recent Activity

Clinical Trials (40)

Showing 20 of 40 trialsScroll for more
NCT07293403Phase 2

Duvelisib Maintenance for the Treatment of Peripheral T-Cell Lymphomas

Recruiting
NCT04803201Phase 2

Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

Suspended
NCT04652960Phase 1

Duvelisib and Nivolumab for the Treatment of Stage IIB-IVB Mycosis Fungoides and Sezary Syndrome

Active Not Recruiting
NCT07714187Phase 1

A Study of Topical Duvelisib in Participants With Early-stage Mycosis Fungoides

Not Yet Recruiting
NCT06810778Phase 1

Duvelisib and Venetoclax in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

Recruiting
NCT07001384Phase 1

A Study of Alectinib and Duvelisib in People With Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma (ALK+ALCL)

Recruiting
NCT04331119Phase 2

Duvelisib Maintenance After Autologous Stem Cell Transplant in T-Cell Lymphomas

Terminated
NCT02783625Phase 1

Trial of Duvelisib in Combination With Either Romidepsin or Bortezomib in Relapsed/Refractory T-cell Lymphomas

Completed
NCT05010005Phase 1

A Study of Ruxolitinib and Duvelisib in People With Lymphoma

Recruiting
NCT03534323Phase 1

Duvelisib and Venetoclax in Relapsed or Refractory CLL or SLL or RS

Active Not Recruiting
NCT06522737Phase 3

A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype

Recruiting
NCT05044039Phase 1

Duvelisib Following Chimeric Antigen Receptor T-Cell Therapy

Active Not Recruiting
NCT03961672Phase 2

Intermittent Duvelisib Dosing in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Active Not Recruiting
NCT04688658Phase 1

Duvelisib in Combination With Nivolumab in Patients With Advanced Unresectable Melanoma

Terminated
NCT05065866Phase 1

Duvelisib in Combination With BMS-986345 in Lymphoid Malignancy

Completed
NCT05057247Phase 2

Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCC

Completed
NCT03372057Phase 2

A Study of Duvelisib in Participants With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

Completed
NCT04890236Early Phase 1

Duvelisib Exposure to Enhance Immune Profiles of T Cells in Patients With Recurrent or Refractory Diffuse Large B-Cell Lymphoma, DEEP T CELLS Study

Completed
NCT04038359Phase 2

A Phase 2 Study Comparing 2 Intermittent Dosing Schedules of Duvelisib in Participants With Indolent Non-Hodgkin Lymphoma

Completed
NCT03892044Phase 1

Duvelisib and Nivolumab in Treating Patients With Richter Syndrome or Transformed Follicular Lymphoma

Completed

Drug Details

Intervention Type
DRUG
Total Trials
40