Success Metrics

Clinical Success Rate
90.4%

Based on 75 completed trials

Completion Rate
90%(75/83)
Active Trials
66(39%)
Results Posted
75%(56 trials)
Terminated
8(5%)

Phase Distribution

Ph phase_2
47
28%
Ph phase_1
9
5%
Ph early_phase_1
4
2%
Ph not_applicable
3
2%
Ph phase_3
32
19%
Ph phase_4
39
23%

Phase Distribution

13

Early Stage

47

Mid Stage

71

Late Stage

Phase Distribution134 total trials
Early Phase 1First-in-human
4(3.0%)
Phase 1Safety & dosage
9(6.7%)
Phase 2Efficacy & side effects
47(35.1%)
Phase 3Large-scale testing
32(23.9%)
Phase 4Post-market surveillance
39(29.1%)
N/ANon-phased studies
3(2.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

87.2%

75 of 86 finished

Non-Completion Rate

12.8%

11 ended early

Currently Active

66

trials recruiting

Total Trials

170

all time

Status Distribution
Active(73)
Completed(75)
Terminated(11)
Other(11)

Detailed Status

Completed75
Recruiting43
Active, not recruiting23
unknown11
Terminated8
Not yet recruiting6

Development Timeline

Analytics

Development Status

Total Trials
170
Active
66
Success Rate
90.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (3.0%)
Phase 19 (6.7%)
Phase 247 (35.1%)
Phase 332 (23.9%)
Phase 439 (29.1%)
N/A3 (2.2%)

Trials by Status

unknown116%
withdrawn32%
terminated85%
recruiting4325%
enrolling_by_invitation11%
active_not_recruiting2314%
completed7544%
not_yet_recruiting64%

Recent Activity

Clinical Trials (170)

Showing 20 of 170 trialsScroll for more
NCT07574294

Dual REmission in Moderate-to-SEvere asthMa and Nasal Polyps

Completed
NCT06369467Phase 1

Short-Term Linvoseltamab Treatment on Top of Chronic Dupilumab Treatment for Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy

Recruiting
NCT06477653Phase 2

Dupilumab as Add-On Therapy for Hypereosinophilic Syndrome With Partial Clinical Response to Eosinophil-Depleting Biologic Agents

Recruiting
NCT05649098Early Phase 1

Repurposing Dupilumab for Management of Pruritic Genetic Inflammatory Skin Disorders

Recruiting
NCT07277322Phase 1

Neoadjuvant Dupilumab and Toripalimab in MSS CRC Subjects With Resectable Liver Metastases

Not Yet Recruiting
NCT06352073Phase 4

Dupilumab for Eosinophilic Esophagitis With Severe Strictures

Active Not Recruiting
NCT05042258Phase 4

Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

Recruiting
NCT07053423Phase 4

A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

Recruiting
NCT06693531

A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

Recruiting
NCT06572228Phase 4

Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison to ICS Dose Escalation to High Dose ICS/LABA in Adolescent and Adult Patients With Uncontrolled Asthma

Recruiting
NCT05097287Phase 4

Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma

Active Not Recruiting
NCT07316114

A Study to Describe the Real-world Effectiveness, Safety and Patterns of Use of Dupilumab in Patients With Chronic Spontaneous Urticaria

Recruiting
NCT05983068Phase 4

A Study of Long-term Effect of Dupilumab on Skin Barrier Function in Pediatric Participants With Atopic Dermatitis

Active Not Recruiting
NCT05263206Phase 3

Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)

Recruiting
NCT07112378Phase 3

A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

Recruiting
NCT07448363

Atopic Dermatitis Treated With Dupilumab and JAK Inhibitors in Costa Rica

Not Yet Recruiting
NCT06461897Phase 3

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Recruiting
NCT07027527Phase 1

An Active Comparator Safety Study Evaluating the Combination of APG777 + APG990 in Moderate-to-Severe Atopic Dermatitis

Active Not Recruiting
NCT06191315Phase 3

Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS)

Recruiting
NCT06881251Phase 2

A Study of JNJ-95475939 in the Treatment of Participants With Moderate to Severe Atopic Dermatitis (AD)

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
170