Success Metrics

Clinical Success Rate
88.4%

Based on 76 completed trials

Completion Rate
88%(76/86)
Active Trials
64(37%)
Results Posted
76%(58 trials)
Terminated
10(6%)

Phase Distribution

Ph not_applicable
3
2%
Ph phase_2
47
27%
Ph phase_4
40
23%
Ph phase_1
10
6%
Ph early_phase_1
4
2%
Ph phase_3
32
19%

Phase Distribution

14

Early Stage

47

Mid Stage

72

Late Stage

Phase Distribution136 total trials
Early Phase 1First-in-human
4(2.9%)
Phase 1Safety & dosage
10(7.4%)
Phase 2Efficacy & side effects
47(34.6%)
Phase 3Large-scale testing
32(23.5%)
Phase 4Post-market surveillance
40(29.4%)
N/ANon-phased studies
3(2.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

85.4%

76 of 89 finished

Non-Completion Rate

14.6%

13 ended early

Currently Active

64

trials recruiting

Total Trials

172

all time

Status Distribution
Active(72)
Completed(76)
Terminated(13)
Other(11)

Detailed Status

Completed76
Recruiting38
Active, not recruiting26
unknown11
Terminated10
Not yet recruiting7

Development Timeline

Analytics

Development Status

Total Trials
172
Active
64
Success Rate
88.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (2.9%)
Phase 110 (7.4%)
Phase 247 (34.6%)
Phase 332 (23.5%)
Phase 440 (29.4%)
N/A3 (2.2%)

Trials by Status

recruiting3822%
enrolling_by_invitation11%
unknown116%
not_yet_recruiting74%
terminated106%
active_not_recruiting2615%
withdrawn32%
completed7644%

Recent Activity

Clinical Trials (172)

Showing 20 of 172 trialsScroll for more
NCT07316114

A Study to Describe the Real-world Effectiveness, Safety and Patterns of Use of Dupilumab in Patients With Chronic Spontaneous Urticaria

Terminated
NCT06881251Phase 2

A Study of JNJ-95475939 in the Treatment of Participants With Moderate to Severe Atopic Dermatitis (AD)

Terminated
NCT07467564

The Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic Dermatitis

Recruiting
NCT05013450Phase 1

Dupilumab_Metastatic NSCLC

Completed
NCT07646548Phase 1

Pharmacokinetics and Tolerability of Subcutaneous Dupilumab Coformulated With Berahyaluronidase Alfa and Dupilumab Without Berahyaluronidase Alfa in Healthy Participants

Active Not Recruiting
NCT06088771Phase 1

Neoadjuvant Dupilumab and Cemiplimab in Patients With Early-stage Resectable NSCLC

Recruiting
NCT03935971Phase 4

The Effects of Dupilumab on Allergic Contact Dermatitis

Active Not Recruiting
NCT06477653Phase 2

Dupilumab as Add-On Therapy for Hypereosinophilic Syndrome With Partial Clinical Response to Eosinophil-Depleting Biologic Agents

Recruiting
NCT06868212Phase 3

A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

Recruiting
NCT05263206Phase 3

Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)

Recruiting
NCT07112378Phase 3

A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

Recruiting
NCT06687967Phase 3

A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 1)

Active Not Recruiting
NCT06687980Phase 3

A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 2)

Active Not Recruiting
NCT05831176Phase 2

A Study to Learn How Well Dupilumab Works in Adult and Adolescent Participants With Eosinophilic Gastritis With or Without Eosinophilic Duodenitis and the Side Effects it May Have

Active Not Recruiting
NCT06192563

A Study to Observe How Adolescent Patients With Severe Atopic Dermatitis Despite Less Extensive Skin Lesions (Eczema Area and Severity Index Score < 16) Respond to Dupilumab Treatment

Recruiting
NCT06631677

Expanded Access of Dupilumab in Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy Previously Treated With Linvoseltamab

Unknown
NCT06369467Phase 1

Short-Term Linvoseltamab Treatment on Top of Chronic Dupilumab Treatment for Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy

Active Not Recruiting
NCT05731128Phase 2

A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))

Active Not Recruiting
NCT06693531

A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

Recruiting
NCT04206553Phase 2

A Study to Evaluate the Efficacy and Safety of Dupilumab in Adult Patients With Bullous Pemphigoid

Completed

Drug Details

Intervention Type
DRUG
Total Trials
172