Success Metrics

Clinical Success Rate
88.0%

Based on 110 completed trials

Completion Rate
88%(110/125)
Active Trials
21(11%)
Results Posted
47%(52 trials)
Terminated
15(8%)

Phase Distribution

Ph not_applicable
36
19%
Ph phase_3
29
15%
Ph phase_4
52
28%
Ph phase_2
48
25%
Ph phase_1
13
7%
Ph early_phase_1
4
2%

Phase Distribution

17

Early Stage

48

Mid Stage

81

Late Stage

Phase Distribution182 total trials
Early Phase 1First-in-human
4(2.2%)
Phase 1Safety & dosage
13(7.1%)
Phase 2Efficacy & side effects
48(26.4%)
Phase 3Large-scale testing
29(15.9%)
Phase 4Post-market surveillance
52(28.6%)
N/ANon-phased studies
36(19.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

81.5%

110 of 135 finished

Non-Completion Rate

18.5%

25 ended early

Currently Active

21

trials recruiting

Total Trials

189

all time

Status Distribution
Active(28)
Completed(110)
Terminated(25)
Other(26)

Detailed Status

Completed110
unknown26
Recruiting15
Terminated15
Withdrawn10
Not yet recruiting6

Development Timeline

Analytics

Development Status

Total Trials
189
Active
21
Success Rate
88.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (2.2%)
Phase 113 (7.1%)
Phase 248 (26.4%)
Phase 329 (15.9%)
Phase 452 (28.6%)
N/A36 (19.8%)

Trials by Status

unknown2614%
not_yet_recruiting63%
recruiting158%
active_not_recruiting63%
withdrawn105%
terminated158%
enrolling_by_invitation11%
completed11058%

Recent Activity

Clinical Trials (189)

Showing 20 of 189 trialsScroll for more
NCT01631617Phase 2

Effects of Treatments on Atopic Dermatitis

Recruiting
NCT06545656Phase 4

Daily Doxycycline to Inform Sexually Transmitted Infection Prophylaxis Regimens

Completed
NCT00353158Phase 1

A Pilot of Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicity

Completed
NCT03511118

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Recruiting
NCT01820910Phase 2

Phase II Trial of First-line Doxycycline for Ocular Adnexal Marginal Zone Lymphoma Treatment

Completed
NCT07544251Phase 4

Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.

Recruiting
NCT02874430Phase 2

Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer

Terminated
NCT03532464Phase 4

Azithromycin Compared With Doxycycline for Treating Anorectal Chlamydia Trachomatis Infection Concomitant to a Vaginal Infection

Completed
NCT03435952Phase 1

Pembrolizumab With Intratumoral Injection of Clostridium Novyi-NT

Active Not Recruiting
NCT06582966Phase 4

Weekly Doxycycline DOT for STI Prevention Among Cisgender Women Taking HIV PrEP in Kisumu, Kenya

Completed
NCT06120140Phase 2

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib

Recruiting
NCT07500415Not Applicable

Doxi-Rio: Study on the Use of Doxycycline to Prevent Sexually Transmitted Infections in Rio de Janeiro

Recruiting
NCT07498010Phase 2

Doxycycline Use in Post-Operative Seromas

Not Yet Recruiting
NCT05840159Phase 4

A Study of Doxycycline to Treat Chlamydial Infection

Completed
NCT07343635Not Applicable

The Efficacy and Safety of Anti-inflammation Treatment (Hirudoid Introduction Followed by Yellow Light Therapy) Combined With Tofacitinib and Doxycycline in Chinese Adult Patients With Mild to Moderate Erythematous Telangiectatic Rosacea

Recruiting
NCT04153604

Doxycycline for the Prevention of Spontaneous Bacterial Peritonitis

Completed
NCT07485010Phase 2

Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform Trial

Not Yet Recruiting
NCT03465774

Indwelling Pleural Catheters With or Without Doxycycline in Treating Patients With Malignant Pleural Effusions

Recruiting
NCT05980871Phase 4

Treatment Responses of Early Syphilis to Ceftriaxone Plus Doxycycline

Terminated
NCT02713607Phase 1

Lipidome and Microbiome Profile of Acne

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
189