Success Metrics

Clinical Success Rate
88.7%

Based on 337 completed trials

Completion Rate
89%(337/380)
Active Trials
63(12%)
Results Posted
42%(142 trials)
Terminated
43(8%)

Phase Distribution

Ph phase_1
85
16%
Ph early_phase_1
3
1%
Ph phase_2
244
45%
Ph phase_3
178
33%
Ph not_applicable
22
4%

Phase Distribution

88

Early Stage

244

Mid Stage

178

Late Stage

Phase Distribution532 total trials
Early Phase 1First-in-human
3(0.6%)
Phase 1Safety & dosage
85(16.0%)
Phase 2Efficacy & side effects
244(45.9%)
Phase 3Large-scale testing
178(33.5%)
N/ANon-phased studies
22(4.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

84.9%

337 of 397 finished

Non-Completion Rate

15.1%

60 ended early

Currently Active

63

trials recruiting

Total Trials

537

all time

Status Distribution
Active(66)
Completed(337)
Terminated(60)
Other(74)

Detailed Status

Completed337
unknown68
Active, not recruiting48
Terminated43
Withdrawn17
Recruiting15

Development Timeline

Analytics

Development Status

Total Trials
537
Active
63
Success Rate
88.7%
Most Advanced
Phase 3

Trials by Phase

Early Phase 13 (0.6%)
Phase 185 (16.0%)
Phase 2244 (45.9%)
Phase 3178 (33.5%)
N/A22 (4.1%)

Trials by Status

suspended61%
unknown6813%
recruiting153%
terminated438%
completed33763%
not_yet_recruiting31%
active_not_recruiting489%
withdrawn173%

Recent Activity

Clinical Trials (537)

Showing 20 of 537 trialsScroll for more
NCT05691478Phase 2

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Recruiting
NCT01424982Phase 2

Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT04978584Phase 2

Rituximab, Lenalidomide, Acalabrutinib, Tafasitamab Alone and With Combination Chemotherapy for the Treatment of Newly Diagnosed Non-germinal Center Diffuse Large B-Cell Lymphoma, Smart Stop Study

Active Not Recruiting
NCT05922904Phase 2

PET Adapted Brentuximab Vedotin and Pembrolizumab in Combination With Doxorubicin and Dacarbazine in Classic Hodgkin Lymphoma

Active Not Recruiting
NCT04799275Phase 2

Testing CC-486 (Oral Azacitidine) Plus the Standard Drug Therapy in Patients 75 Years or Older With Newly Diagnosed Diffuse Large B Cell Lymphoma

Suspended
NCT04628767Phase 2

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Recruiting
NCT04530565Phase 3

Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

Active Not Recruiting
NCT03914625Phase 3

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

Active Not Recruiting
NCT04759586Phase 3

Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma

Active Not Recruiting
NCT02166463Phase 3

Brentuximab Vedotin and Combination Chemotherapy in Treating Children and Young Adults With Stage IIB, Stage IIIB, IVA, or IVB Hodgkin Lymphoma

Active Not Recruiting
NCT02306161Phase 3

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

Active Not Recruiting
NCT03269669Phase 2

Obinutuzumab With or Without Umbralisib, Lenalidomide, or Combination Chemotherapy in Treating Patients With Relapsed or Refractory Grade I-IIIa Follicular Lymphoma

Active Not Recruiting
NCT04301076Phase 1

Testing the Addition of an Anti-cancer Drug, Lenalidomide, to the Usual Combination Chemotherapy Treatment ("EPOCH") for Adult T-Cell Leukemia-Lymphoma (ATLL)

Suspended
NCT03220022Phase 1

Ibrutinib, Rituximab, Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell Lymphomas

Active Not Recruiting
NCT02180867Phase 2

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Active Not Recruiting
NCT03907488Phase 3

Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

Active Not Recruiting
NCT03984448Phase 2

Testing the Addition of a New Anti-cancer Drug, Venetoclax, to Usual Chemotherapy for High Grade B-cell Lymphomas

Active Not Recruiting
NCT01856192Phase 2

Rituximab and Combination Chemotherapy With or Without Lenalidomide in Treating Patients With Newly Diagnosed Stage II-IV Diffuse Large B Cell Lymphoma

Active Not Recruiting
NCT00740805Phase 1

Veliparib, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Non-Hodgkin Lymphoma

Active Not Recruiting
NCT05675410Phase 3

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
537