Success Metrics

Clinical Success Rate
50.0%

Based on 8 completed trials

Completion Rate
50%(8/16)
Active Trials
49(62%)
Results Posted
200%(16 trials)
Terminated
8(10%)

Phase Distribution

Ph phase_1
23
29%
Ph phase_4
2
3%
Ph phase_2
43
54%
Ph phase_3
9
11%

Phase Distribution

23

Early Stage

43

Mid Stage

11

Late Stage

Phase Distribution77 total trials
Phase 1Safety & dosage
23(29.9%)
Phase 2Efficacy & side effects
43(55.8%)
Phase 3Large-scale testing
9(11.7%)
Phase 4Post-market surveillance
2(2.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

38.1%

8 of 21 finished

Non-Completion Rate

61.9%

13 ended early

Currently Active

49

trials recruiting

Total Trials

79

all time

Status Distribution
Active(56)
Completed(8)
Terminated(13)
Other(2)

Detailed Status

Active, not recruiting25
Recruiting24
Completed8
Terminated8
Not yet recruiting7
Withdrawn5

Development Timeline

Analytics

Development Status

Total Trials
79
Active
49
Success Rate
50.0%
Most Advanced
Phase 4

Trials by Phase

Phase 123 (29.9%)
Phase 243 (55.8%)
Phase 39 (11.7%)
Phase 42 (2.6%)

Trials by Status

completed810%
not_yet_recruiting79%
terminated810%
withdrawn56%
recruiting2430%
unknown23%
active_not_recruiting2532%

Recent Activity

Clinical Trials (79)

Showing 20 of 79 trialsScroll for more
NCT03843359Phase 1

A First Time in Human (FTIH) Study of GSK3745417 Administered to Participants With Advanced Solid Tumors

Terminated
NCT07740720Phase 3

A Study of the Duration of Dostarlimab in Untreated Mismatch Repair Deficient (dMMR)/ Microsatellite Instability-high (MSI-H) Locally Advanced Rectal Cancer

Not Yet Recruiting
NCT06472076Phase 3

A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)

Active Not Recruiting
NCT07684599Phase 3

A Study to Investigate GSK5733584 as Maintenance Treatment for Participants With MMRp Endometrial Cancer (BEHOLD-Endometrial02)

Not Yet Recruiting
NCT04774419Phase 2

Radiation and TSR-042 (Dostarlimab) in People With Endometrial Cancer After They Receive Surgery

Recruiting
NCT06796907Phase 1

A Study of Mocertatug Rezetecan in Combination With Anti-cancer Therapies for Advanced Solid Tumors (BEHOLD-2)

Recruiting
NCT04655976Phase 2

Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-small Cell Lung Cancer Who Have Progressed on Prior Anti-PD-(L)1 Therapy and Chemotherapy

Active Not Recruiting
NCT04926324Phase 1

A Safety Study Adding Niraparib and Dostarlimab to Radiation Therapy for Rectal Cancers

Terminated
NCT05277051Phase 1

First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors

Active Not Recruiting
NCT06062420Phase 2

A Platform Study of Novel Immunotherapy Combinations as First-Line Treatment in Participants With PD-L1 Positive Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck- GALAXIES H&N-202

Active Not Recruiting
NCT06065462Phase 1

Safety and Efficacy of Targeting PP2A in Ovarian Clear Cell Carcinoma Using Dostarlimab and LB-100

Recruiting
NCT04837209Phase 2

Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast Cancer

Active Not Recruiting
NCT07652515Phase 4

A Study to Evaluate the Safety of Dostarlimab in Adult Participants in India With Primary Advanced or Recurrent Endometrial Cancer

Not Yet Recruiting
NCT05565378Phase 2

A Platform Study of Novel Immunotherapy Combinations in Participants With Previously Untreated, Advanced/Metastatic Non-Small-Cell Lung Cancer

Active Not Recruiting
NCT05239546Phase 2

Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers

Recruiting
NCT05819892Phase 1

Phase I Trial Testing the Safety and Tolerability of Chemoradiation Followed by Chemotherapy + Dostarlimab for Stage IIIC, Node Positive, Endometrial Cancer

Recruiting
NCT05784012Phase 1

Two-cohort Study of Niraparib and Dostarlimab Plus (Chemo)RadIotherapy in Locally-Advanced Head and Neck Squamous Cell Carcinoma

Active Not Recruiting
NCT05723562Phase 2

A Study of Dostarlimab in Untreated dMMR/MSI-H Locally Advanced Rectal Cancer

Active Not Recruiting
NCT06256588Phase 3

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

Recruiting
NCT06567782Phase 2

A Study of Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer

Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
79