Success Metrics

Completion Rate

0%(0/3)

Active Trials

2(29%)

Terminated

3(43%)

Phase Distribution

Ph phase_1

86%

Ph not_applicable

14%

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution7 total trials

Phase 1Safety & dosage

6(85.7%)

N/ANon-phased studies

1(14.3%)

Highest Phase Reached

Phase 1

Trial Status & Enrollment

Completion Rate

0.0%

0 of 3 finished

Non-Completion Rate

100.0%

3 ended early

Currently Active

trials recruiting

Total Trials

all time

Status Distribution

Active(2)

Terminated(3)

Other(2)

Detailed Status

Terminated3

unknown2

Active, not recruiting1

Recruiting1

Development Timeline

Analytics

Development Status

Total Trials

Active

Success Rate

0.0%

Most Advanced

Phase 1

Trials by Phase

Phase 16 (85.7%)

N/A1 (14.3%)

Trials by Status

active_not_recruiting114%

recruiting114%

terminated343%

unknown229%

Recent Activity

2 active trials

Showing 5 of 7

terminatedphase_1

A Phase 1/2 Study of Donafenib in Combination With KN046 in Advanced Gastrointestinal Tumors

NCT04612712

recruitingphase_1

A Study of ZG005 Combined With Donafenib in Patients With Advanced Solid Tumor

NCT06239298

active_not_recruitingphase_1

Donafenib and Toripalimab Combined With TACE in Patients With Unresectable Hepatocellular Carcinoma

NCT04605185

unknownnot_applicable

A Study Evaluating the Efficacy and Safety of ZG005 in Combination With Donafenib or Bevacizumab in Patients With Advanced Hepatocellular Carcinoma

NCT06233994

terminatedphase_1

A Study of Donafenib Monotherapy in Advanced Oesophageal Cancer

NCT02489201

View all 7 trials

Clinical Trials (7)

Showing 7 of 7 trials

NCT04612712Phase 1

A Phase 1/2 Study of Donafenib in Combination With KN046 in Advanced Gastrointestinal Tumors

Terminated

NCT06239298Phase 1

A Study of ZG005 Combined With Donafenib in Patients With Advanced Solid Tumor

Recruiting

NCT04605185Phase 1

Donafenib and Toripalimab Combined With TACE in Patients With Unresectable Hepatocellular Carcinoma

Active Not Recruiting

NCT06233994Not Applicable

A Study Evaluating the Efficacy and Safety of ZG005 in Combination With Donafenib or Bevacizumab in Patients With Advanced Hepatocellular Carcinoma

Unknown

NCT02489201Phase 1

A Study of Donafenib Monotherapy in Advanced Oesophageal Cancer

Terminated

NCT02489214Phase 1

Donafenib Monotherapy for Previously Treated Metastatic Gastric Cancer

Terminated

NCT04503902Phase 1

Toripalimab Combined With Donafenib in the Treatment of Advanced Hepatocellular Carcinoma

Unknown

All 7 trials loaded

Drug Details

Intervention Type: DRUG
Total Trials: 7