Success Metrics

Clinical Success Rate
100.0%

Based on 2 completed trials

Completion Rate
100%(2/2)
Active Trials
13(76%)
Results Posted
0%(0 trials)

Phase Distribution

Ph early_phase_1
1
6%
Ph phase_3
3
18%
Ph phase_2
11
65%
Ph phase_1
2
12%

Phase Distribution

3

Early Stage

11

Mid Stage

3

Late Stage

Phase Distribution17 total trials
Early Phase 1First-in-human
1(5.9%)
Phase 1Safety & dosage
2(11.8%)
Phase 2Efficacy & side effects
11(64.7%)
Phase 3Large-scale testing
3(17.6%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

66.7%

2 of 3 finished

Non-Completion Rate

33.3%

1 ended early

Currently Active

13

trials recruiting

Total Trials

17

all time

Status Distribution
Active(13)
Completed(2)
Terminated(1)
Other(1)

Detailed Status

Active, not recruiting11
Completed2
Recruiting2
Withdrawn1
Suspended1

Development Timeline

Analytics

Development Status

Total Trials
17
Active
13
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (5.9%)
Phase 12 (11.8%)
Phase 211 (64.7%)
Phase 33 (17.6%)

Trials by Status

active_not_recruiting1165%
completed212%
recruiting212%
withdrawn16%
suspended16%

Recent Activity

Clinical Trials (17)

Showing 17 of 17 trials
NCT04791839Phase 2

Safety and Efficacy of Zimberelimab (AB122) in Combination With Domvanalimab (AB154) and Etrumadenant (AB928) in Patients With Previously Treated Non-Small Cell Lung Cancer

Active Not Recruiting
NCT04736173Phase 2

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Active Not Recruiting
NCT05329766Phase 2

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Active Not Recruiting
NCT05211895Phase 3

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

Recruiting
NCT04656535Early Phase 1

AB154 Combined With AB122 for Recurrent Glioblastoma

Active Not Recruiting
NCT05568095Phase 3

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Active Not Recruiting
NCT05130177Phase 2

Zimberelimab (AB122) With TIGIT Inhibitor Domvanalimab (AB154) in PD-1 Relapsed/Refractory Melanoma

Active Not Recruiting
NCT03547973Phase 2

Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

Recruiting
NCT06133517Phase 2

PeRioperative Immunotherapy Combined With Sacituzumab Govitecan in Muscle Invasive blAdder Cancer

Active Not Recruiting
NCT06727565Phase 2

Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01

Active Not Recruiting
NCT05419479Phase 1

Switch Maintenance in Pancreatic

Suspended
NCT05502237Phase 3

Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer

Active Not Recruiting
NCT07283848Phase 2

Zimberelimab + Domvanalimab in Gastroesophageal Adenocarcinoma

Withdrawn
NCT05676931Phase 2

Study With Various Immunotherapy Treatments in Participants With Lung Cancer

Active Not Recruiting
NCT04262856Phase 2

Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer

Completed
NCT05724563Phase 2

Domvanalimab and Zimberelimab in Advanced Liver Cancers

Active Not Recruiting
NCT03628677Phase 1

A Study to Evaluate the Safety and Tolerability of AB154 in Participants With Advanced Malignancies

Completed

All 17 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
17