Dolutegravir
Dolutegravir is a pharmaceutical drug with 71 clinical trials. Currently 7 active trials ongoing. Historical success rate of 90.0%.
Success Metrics
Based on 45 completed trials
Phase Distribution
Phase Distribution
19
Early Stage
11
Mid Stage
29
Late Stage
Highest Phase Reached
Phase 4Trial Status & Enrollment
84.9%
45 of 53 finished
15.1%
8 ended early
7
trials recruiting
71
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
A Clinical Trial of MK-4646 With Bictegravir/Emtricitabine/Tenofovir Alafenamide and Dolutegravir in Healthy Adult Participants (MK-4646)
Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study
Doravirine Dose Optimisation in Pregnancy
A Study of Daily Rifapentine Combined With Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age With and Without HIV
Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment (DOLPHIN KIDS)
Clinical Trials (71)
A Clinical Trial of MK-4646 With Bictegravir/Emtricitabine/Tenofovir Alafenamide and Dolutegravir in Healthy Adult Participants (MK-4646)
Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study
Doravirine Dose Optimisation in Pregnancy
A Study of Daily Rifapentine Combined With Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age With and Without HIV
Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment (DOLPHIN KIDS)
A Study to Evaluate the Efficacy, Safety, and Tolerability of Using an Oral Once-daily 2 Drug Regimen Compared to an Oral Once-daily 3 Drug Regimen for the Treatment of Human Immunodeficiency Virus (HIV)-1 in Adults Who Have Not Previously Taken Antiretroviral Therapy
Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy
The Effect of Dolutegravir on Whole-body Insulin Sensitivity, Lipid and Endocrine Profile in Healthy Volunteers
Population Pharmacokinetics of Antiretroviral in Children
Multi Interventional Approaches to Mitigate HIV Reservoirs Aiming the Sustained HIV Remission Without Antiretrovirals
ODYSSEY (PENTA 20)
Immediate Initiation of Antiretroviral Therapy During "Hyperacute" HIV Infection
Dolutegravir in Pregnant HIV Mothers and Their Neonates
Pharmacokinetics of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants Under 6 Months of Age in Botswana
National Multicenter Trial Evaluating Two Treatments in Patients with Primary Human Immunodeficiency Virus (HIV-1) Infection
Dolutegravir Pharmacokinetics During Weekly Rifapentine/Isoniazid for TB Prevention
Drug Interactions Between Dolutegravir and Escalating Doses of Rifampicin
A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults
Gut Microbiota, PGx and INSTIs Response
HERV-K Suppression Using Antiretroviral Therapy in Volunteers With Amyotrophic Lateral Sclerosis (ALS)
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 71