Success Metrics

Active Trials
20(56%)

Phase Distribution

Ph phase_3
4
11%
Ph not_applicable
1
3%
Ph phase_2
25
69%
Ph phase_1
4
11%

Phase Distribution

4

Early Stage

25

Mid Stage

4

Late Stage

Phase Distribution34 total trials
Phase 1Safety & dosage
4(11.8%)
Phase 2Efficacy & side effects
25(73.5%)
Phase 3Large-scale testing
4(11.8%)
N/ANon-phased studies
1(2.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

0.0%

0 of 1 finished

Non-Completion Rate

100.0%

1 ended early

Currently Active

20

trials recruiting

Total Trials

36

all time

Status Distribution
Active(28)
Terminated(1)
Other(7)

Detailed Status

Recruiting17
Not yet recruiting8
unknown7
Active, not recruiting3
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
36
Active
20
Success Rate
N/A
Most Advanced
Phase 3

Trials by Phase

Phase 14 (11.8%)
Phase 225 (73.5%)
Phase 34 (11.8%)
N/A1 (2.9%)

Trials by Status

active_not_recruiting38%
unknown719%
withdrawn13%
not_yet_recruiting822%
recruiting1747%

Recent Activity

Clinical Trials (36)

Showing 20 of 36 trialsScroll for more
NCT06157892Phase 2

A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors

Recruiting
NCT06966453Phase 1

A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer

Recruiting
NCT04879329Phase 2

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

Recruiting
NCT05911295Phase 3

Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2

Active Not Recruiting
NCT07474064Phase 2

Probiotics Combined With Targeted Therapy Plus Immunotherapy in Bladder-Preserving Setting for Patients With MIBC

Not Yet Recruiting
NCT06003231Phase 2

A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2

Active Not Recruiting
NCT07366840Phase 2

RC48 Combined With Chemotherapy in HER2-Positive Advanced Breast Cancer Patients With Prior TOP1i-ADC Failure

Not Yet Recruiting
NCT07315750Phase 3

A Study of Disitamab Vedotin Combined With Trastuzumab and Tislelizumab Versus Chemotherapy Combined With Trastuzumab With or Without Pembrolizumab in HER2-high Expression Advanced Gastric or Gastroesophageal Junction Adenocarcinoma.

Recruiting
NCT06210490Phase 2

A Clinical Study of the Efficacy and Safety of Disitamab Vedotin in Combination With Radiotherapy for the Adjuvant Treatment of HER2 Overexpressing UTUC Patients With High Risk Factors for Recurrence After Radical Surgery

Recruiting
NCT05831878Not Applicable

RC48-ADC in HER2-low Advanced Breast Cancer

Recruiting
NCT05851677

Disitamab Vedotin (RC48-ADC) in Breast Cancer

Recruiting
NCT07159217Phase 2

Disitamab Vedotin Plus Lenvatinib and PD-1 Inhibitors for Treating HER2-positive Advanced Biliary Tract Cancer

Not Yet Recruiting
NCT07142200Phase 2

A Clinical Study Evaluating the Efficacy and Safety of Disitamab Vedotin Combined With PD-1 Inhibitor and Radiotherapy as Bladder-preserving Therapy in Patients With Localized HER2-high Expressing Muscle-invasive Bladder Urothelial Carcinoma Following Maximal Transurethral Resection

Not Yet Recruiting
NCT06904573Phase 2

Probiotics in Advanced Urothelial Carcinoma

Recruiting
NCT06642545Phase 2

Efficacy and Safety Study of Disitamab Vedotin + RC148 vs. Albumin-Paclitaxone ± Toripalimab in HR-/HER2-low Breast Cancer

Recruiting
NCT05586061Phase 2

First-line Treatment with RC48 Plus Tislelizumab and S-1(RCTS) in Advanced Gastric Cancer

Active Not Recruiting
NCT06730373Phase 2

First-line Treatment With RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2)

Recruiting
NCT06650332Phase 1

Cadonilimab Combination Regimen as First-line Treatment for HER2-expressing GC/GEJ Patients

Recruiting
NCT06105008Phase 2

Study of Disitamab Vedotin With Toripalimab Verus Disitamab Vedotin in Hormone Receptor Positive, HER2-low Locally Advanced or Metastatic Breast Cancer

Withdrawn
NCT06187506Phase 2

Disitamab Vedotin Combined With BCG Therapy in HER2-expressing High-risk Non-muscle Invasive Bladder Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
36