Success Metrics

Clinical Success Rate
83.3%

Based on 15 completed trials

Completion Rate
83%(15/18)
Active Trials
0(0%)
Results Posted
20%(3 trials)
Terminated
3(17%)

Phase Distribution

Ph phase_2
3
17%
Ph phase_1
9
50%
Ph phase_3
6
33%

Phase Distribution

9

Early Stage

3

Mid Stage

6

Late Stage

Phase Distribution18 total trials
Phase 1Safety & dosage
9(50.0%)
Phase 2Efficacy & side effects
3(16.7%)
Phase 3Large-scale testing
6(33.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

83.3%

15 of 18 finished

Non-Completion Rate

16.7%

3 ended early

Currently Active

0

trials recruiting

Total Trials

18

all time

Status Distribution
Completed(15)
Terminated(3)

Detailed Status

Completed15
Terminated3

Development Timeline

Analytics

Development Status

Total Trials
18
Active
0
Success Rate
83.3%
Most Advanced
Phase 3

Trials by Phase

Phase 19 (50.0%)
Phase 23 (16.7%)
Phase 36 (33.3%)

Trials by Status

terminated317%
completed1583%

Recent Activity

Clinical Trials (18)

Showing 18 of 18 trials
NCT00838110Phase 3

A Phase 3 Study To Evaluate The Safety And Tolerability Of Dimebon Patients With Mild To Moderate Alzheimer's Disease

Completed
NCT00827034Phase 1

A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects

Completed
NCT00920946Phase 3

A Safety and Efficacy Study of Dimebon in Patients With Huntington Disease

Completed
NCT00829374Phase 3

Safety and Efficacy Study Evaluating Dimebon in Patients With Mild to Moderate Alzheimer's Disease on Donepezil

Completed
NCT00675623Phase 3

A Safety and Efficacy Study of Oral Dimebon in Patients With Mild-To-Moderate Alzheimer's Disease

Completed
NCT01152216Phase 3

An Extension of the CONCERT Protocol (DIM18)

Terminated
NCT00704782Phase 2

Study of Combination Therapy With Dimebon and Donepezil (Aricept) in Patients With Alzheimer's Disease

Terminated
NCT00377715Phase 2

Double-blind, Placebo-controlled Study of Oral Dimebon in Subjects With Mild to Moderate Alzheimer's Disease

Completed
NCT00829816Phase 1

Safety and Tolerability of Dimebon in Patients on Memantine, and Memantine Plus Donepezil

Completed
NCT00497159Phase 2

A Study of the Novel Drug Dimebon in Patients With Huntington's Disease

Completed
NCT00975481Phase 1

A Study To Evaluate The Abuse Potential Of Single Oral Doses Of Dimebon (Latrepirdine) In Healthy Recreational Polydrug Users

Completed
NCT00939783Phase 3

An Extension To The B1451027 Protocol To Evaluate The Long Term Safety And Tolerability Of Dimebon In Patients With Alzheimer's Disease

Terminated
NCT00825084Phase 1

A Phase 1 Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF-01913539] In Japanese And Western Healthy Subjects

Completed
NCT00824590Phase 1

A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function

Completed
NCT00831532Phase 1

Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [Pf-01913539] In Subjects With Hepatic Impairment And Normal Hepatic Function

Completed
NCT00907322Phase 1

A Phase 1 Trial To Assess The Safety And Pharmacokinetics Of Single, Ascending, Oral Doses Of Dimebon In Healthy Adults

Completed
NCT00831506Phase 1

Dimebon (PF-01913539)-Digoxin Drug-Drug Interaction Study In Healthy Subjects

Completed
NCT00387270Phase 1

Safety Study of the Novel Drug Dimebon to Treat Patients With Huntington's Disease

Completed

All 18 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
18