Success Metrics

Clinical Success Rate
75.0%

Based on 3 completed trials

Completion Rate
75%(3/4)
Active Trials
2(25%)
Results Posted
67%(2 trials)
Terminated
1(13%)

Phase Distribution

Ph phase_2
3
38%
Ph not_applicable
1
13%
Ph phase_3
1
13%
Ph phase_1
2
25%

Phase Distribution

2

Early Stage

3

Mid Stage

1

Late Stage

Phase Distribution7 total trials
Phase 1Safety & dosage
2(28.6%)
Phase 2Efficacy & side effects
3(42.9%)
Phase 3Large-scale testing
1(14.3%)
N/ANon-phased studies
1(14.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

60.0%

3 of 5 finished

Non-Completion Rate

40.0%

2 ended early

Currently Active

2

trials recruiting

Total Trials

8

all time

Status Distribution
Active(2)
Completed(3)
Terminated(2)
Other(1)

Detailed Status

Completed3
Active, not recruiting2
Withdrawn1
unknown1
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
8
Active
2
Success Rate
75.0%
Most Advanced
Phase 3

Trials by Phase

Phase 12 (28.6%)
Phase 23 (42.9%)
Phase 31 (14.3%)
N/A1 (14.3%)

Trials by Status

completed338%
withdrawn113%
active_not_recruiting225%
unknown113%
terminated113%

Recent Activity

2 active trials
Showing 5 of 8
active_not_recruitingphase_2

Trial of Dichloroacetate (DCA) in Glioblastoma Multiforme (GBM)

NCT05120284
unknown

Expanded Access Treatment Protocol With DCA for Patients With PDCD

NCT06931262
active_not_recruitingphase_3

Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:

NCT02616484
completedphase_1

A Pilot Study of Rapid Haplotyping Procedure for Personalized Dosing of Dichloroacetate (DCA) in Healthy Volunteers

NCT02690285
withdrawnphase_1

Combining Radiotherapy and Temozolomide With Dichloroacetate in Patients With Newly Diagnosed Glioblastoma

NCT00703859
View all 8 trials

Clinical Trials (8)

Showing 8 of 8 trials
NCT05120284Phase 2

Trial of Dichloroacetate (DCA) in Glioblastoma Multiforme (GBM)

Active Not Recruiting
NCT06931262

Expanded Access Treatment Protocol With DCA for Patients With PDCD

Unknown
NCT02616484Phase 3

Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:

Active Not Recruiting
NCT02690285Phase 1

A Pilot Study of Rapid Haplotyping Procedure for Personalized Dosing of Dichloroacetate (DCA) in Healthy Volunteers

Completed
NCT00703859Phase 1

Combining Radiotherapy and Temozolomide With Dichloroacetate in Patients With Newly Diagnosed Glioblastoma

Withdrawn
NCT01029925Phase 2

Dichloroacetate (DCA) in Patients With Previously Treated Metastatic Breast or Non-Small Cell Lung Cancer (NSCL)

Terminated
NCT00874276Not Applicable

Pharmacotoxicology of Trichloroethylene Metabolites

Completed
NCT00540176Phase 2

The Safety and Efficacy of DCA for the Treatment of Brain Cancer

Completed

All 8 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
8