Success Metrics

Clinical Success Rate
88.2%

Based on 15 completed trials

Completion Rate
88%(15/17)
Active Trials
1(4%)
Results Posted
53%(8 trials)
Terminated
2(8%)

Phase Distribution

Ph phase_2
10
38%
Ph phase_1
3
12%
Ph phase_3
3
12%
Ph phase_4
5
19%
Ph not_applicable
1
4%
Ph early_phase_1
1
4%

Phase Distribution

4

Early Stage

10

Mid Stage

8

Late Stage

Phase Distribution23 total trials
Early Phase 1First-in-human
1(4.3%)
Phase 1Safety & dosage
3(13.0%)
Phase 2Efficacy & side effects
10(43.5%)
Phase 3Large-scale testing
3(13.0%)
Phase 4Post-market surveillance
5(21.7%)
N/ANon-phased studies
1(4.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

78.9%

15 of 19 finished

Non-Completion Rate

21.1%

4 ended early

Currently Active

1

trials recruiting

Total Trials

26

all time

Status Distribution
Active(1)
Completed(15)
Terminated(4)
Other(6)

Detailed Status

Completed15
unknown6
Terminated2
Withdrawn2
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
26
Active
1
Success Rate
88.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (4.3%)
Phase 13 (13.0%)
Phase 210 (43.5%)
Phase 33 (13.0%)
Phase 45 (21.7%)
N/A1 (4.3%)

Trials by Status

unknown623%
recruiting14%
terminated28%
completed1558%
withdrawn28%

Recent Activity

Clinical Trials (26)

Showing 20 of 26 trialsScroll for more
NCT02164253Phase 2

Focal Accumulation of Iron in Cerebral Regions in Early ALS (Amyotrophic Lateral Sclerosis) Patients

Completed
NCT02655315Phase 2

Conservative Iron Chelation as a Disease-modifying Strategy in Parkinson's Disease

Completed
NCT03293069Phase 2

Conservative Iron Chelation as a Disease-modifying Strategy in Amyotrophic Lateral Sclerosis

Completed
NCT07023666Phase 2

Early Screening and Treatment of Heart Complication in Sickle Cell Disease

Recruiting
NCT02728843Phase 2

Study of Parkinson's Early Stage With Deferiprone

Completed
NCT02443545Phase 4

Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias

Terminated
NCT00907283Phase 2

Ferrochelating Treatment in Patients Affected by Neurodegeneration With Brain Iron Accumulation (NBIA)

Unknown
NCT02635841

Compassionate Use of Deferiprone in Patients With PKAN

Unknown
NCT02041299Phase 4

Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other Anemias

Terminated
NCT01825512Phase 3

Efficacy/Safety Study of Deferiprone Compared to Deferasirox in Paediatric Patients

Completed
NCT01391520Phase 3

Efficacy and Safety of Deferiprone in Patients With Chronic Kidney Disease Undergoing a Cardiac Catheterization and Receiving Contrast Agent

Withdrawn
NCT02880033Not Applicable

Oxidative Stress and Apoptosis of Energy Metabolism by Deferiprone From the Circulating Lymphocytes

Completed
NCT02477631Phase 2

Effect of Deferiprone on Oxidative-Stress and Iron-Overload in Low Risk Transfusion-Dependent MDS Patients

Completed
NCT02878538Early Phase 1

A Pilot of the Feasibility of Using the Iron-Chelator Deferiprone on Mild Cognitive Impairment

Withdrawn
NCT02882477Phase 2

Treatment of Wolfram Syndrome Type 2 With the Chelator Deferiprone and Incretin Based Therapy

Unknown
NCT02173951Phase 2

An Algorithm to Start Iron Chelation in Minimally Transfused Young Beta-thalassemia Major Patients

Unknown
NCT01989455Phase 1

A Blinded, Placebo-Controlled Study of the Safety and Pharmacokinetics of Single Doses of Intravenous Deferiprone in Healthy Volunteers

Completed
NCT01860703Phase 4

Evaluation of Whether Deferiprone Affects QT Interval in Healthy Subjects

Completed
NCT01770652Phase 4

An Open-label, Non-randomized, Parallel Group Study in Subjects With Mild, Moderate, Severe, or No Renal Impairment

Completed
NCT02191657Phase 1

Antiretroviral Activity and Pharmacokinetics of Deferiprone in Healthy Volunteers and Asymptomatic HIV-infected Subjects

Completed

Drug Details

Intervention Type
DRUG
Total Trials
26