Success Metrics

Active Trials
14(100%)

Phase Distribution

Ph phase_1
4
29%
Ph phase_3
7
50%
Ph phase_2
3
21%

Phase Distribution

4

Early Stage

3

Mid Stage

7

Late Stage

Phase Distribution14 total trials
Phase 1Safety & dosage
4(28.6%)
Phase 2Efficacy & side effects
3(21.4%)
Phase 3Large-scale testing
7(50.0%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

0.0%

0 of 0 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

14

trials recruiting

Total Trials

14

all time

Status Distribution
Active(14)

Detailed Status

Recruiting9
Active, not recruiting5

Development Timeline

Analytics

Development Status

Total Trials
14
Active
14
Success Rate
N/A
Most Advanced
Phase 3

Trials by Phase

Phase 14 (28.6%)
Phase 23 (21.4%)
Phase 37 (50.0%)

Trials by Status

recruiting964%
active_not_recruiting536%

Recent Activity

Clinical Trials (14)

Showing 14 of 14 trials
NCT05104866Phase 3

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

Active Not Recruiting
NCT06103864Phase 3

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

Recruiting
NCT07098338Phase 2

A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT07535437Phase 1

A Study of Ivonescimab in Combination With Dato-DXd or Osimertinib in People With Non-Small Cell Lung Cancer

Recruiting
NCT07205822Phase 3

A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer

Recruiting
NCT06112379Phase 3

A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer

Active Not Recruiting
NCT07129993Phase 2

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

Recruiting
NCT05629585Phase 3

A Study of Dato-DXd With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy (TROPION-Breast03)

Active Not Recruiting
NCT05061550Phase 2

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

Recruiting
NCT06417814Phase 3

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Recruiting
NCT04644068Phase 1

Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

Active Not Recruiting
NCT06244485Phase 1

A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors

Recruiting
NCT05374512Phase 3

A Study of Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02)

Active Not Recruiting
NCT06508216Phase 1

A Study to Explore Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of Novel Therapeutics in Patients With Early Relapsed Metastatic Triple-negative Breast Cancer

Recruiting

All 14 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
14