Success Metrics

Clinical Success Rate
89.7%

Based on 52 completed trials

Completion Rate
90%(52/58)
Active Trials
0(0%)
Results Posted
50%(26 trials)
Terminated
6(9%)

Phase Distribution

Ph phase_3
14
22%
Ph phase_1
25
39%
Ph phase_4
13
20%
Ph phase_2
9
14%

Phase Distribution

25

Early Stage

9

Mid Stage

27

Late Stage

Phase Distribution61 total trials
Phase 1Safety & dosage
25(41.0%)
Phase 2Efficacy & side effects
9(14.8%)
Phase 3Large-scale testing
14(23.0%)
Phase 4Post-market surveillance
13(21.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

85.2%

52 of 61 finished

Non-Completion Rate

14.8%

9 ended early

Currently Active

0

trials recruiting

Total Trials

64

all time

Status Distribution
Completed(52)
Terminated(9)
Other(3)

Detailed Status

Completed52
Terminated6
unknown3
Withdrawn3

Development Timeline

Analytics

Development Status

Total Trials
64
Active
0
Success Rate
89.7%
Most Advanced
Phase 4

Trials by Phase

Phase 125 (41.0%)
Phase 29 (14.8%)
Phase 314 (23.0%)
Phase 413 (21.3%)

Trials by Status

terminated69%
unknown35%
completed5281%
withdrawn35%

Recent Activity

Clinical Trials (64)

Showing 20 of 64 trialsScroll for more
NCT03194165

Population Pharmacokinetics of Antiretroviral in Children

Completed
NCT02470650Phase 4

Cost-effectiveness of Different Antiretroviral Treatment in Patients HIV Naive

Withdrawn
NCT04208061Phase 1

A Study of Darunavir in Combination With Cobicistat or Ritonavir, and Dabigatran Etexilate in Healthy Participants

Completed
NCT04718805Phase 1

A Study of Darunavir in the Presence of Cobicistat When Administered as a Fixed Dose Combination Under Fed Conditions

Completed
NCT02578550Phase 1

A Bioequivalence Study of Darunavir, Emtricitabine, and Tenofovir Alafenamide, in the Presence of Cobicistat in Healthy Participants

Completed
NCT04661397Phase 1

A Study in Healthy Participants to Assess the Effect of Darunavir, Emtricitabine, and Tenofovir Alafenamide in the Presence of Cobicistat as Fixed Dose Combination (Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide) Compared With Co-administration of the Separate Agents

Completed
NCT01400412Phase 2

Bone, Immunologic, and Virologic Effects of a Antiretroviral Regimen

Completed
NCT02275780Phase 3

Safety and Efficacy of Doravirine (MK-1439) in Participants With Human Immunodeficiency Virus 1 (HIV-1) (MK-1439-018)

Completed
NCT02437110Phase 1

HERV-K Suppression Using Antiretroviral Therapy in Volunteers With Amyotrophic Lateral Sclerosis (ALS)

Completed
NCT01605084Phase 3

Second-line Treatment of HIV-1 With Ritonavir Boosted Atazanavir or Darunavir With an Optimized NRTI Backbone

Withdrawn
NCT02475915Phase 1

Efficacy of VHM After Treatment Interruption in Subjects Initiating ART During Acute HIV Infection

Completed
NCT03017872Phase 4

Dolutegravir and Darunavir Evaluation in Adults Failing Therapy

Unknown
NCT01281813Phase 3

TMC114IFD3001 - Study Providing Continued Access to Treatment With Darunavir (DRV)/Ritonavir(Rtv) in HIV1 Infected Adults, Adolescents and Children Aged 3 Years or Above and Coming From Previous Company Sponsored Studies With DRV

Completed
NCT00260078Phase 1

Blood Levels of Anti-HIV Drugs Used in Combination Regimens in HIV Infected Children

Completed
NCT00537394Phase 3

Optimizing Treatment for Treatment-Experienced, HIV-Infected People

Completed
NCT04183738Phase 4

Inflammation and Co-Infections in D²EFT

Withdrawn
NCT01695954Phase 1

Pharmacokinetic Study of Pitavastatin and Ritonavir-Boosted Darunavir or Efavirenz

Completed
NCT03988452Phase 3

Nucleosides And Darunavir/Dolutegravir In Africa

Unknown
NCT04236453Phase 1

A Study in Healthy Participants to Assess the Effect of Darunavir, Emtricitabine, and Tenofovir Alafenamide in the Presence of Cobicistat When Administered as a Fixed Dose Combination (Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide) Compared to the Co-administration of the Separate Agents

Terminated
NCT01348763Phase 1

The Maraviroc Darunavir/Ritonavir Once Daily Pharmacokinetic Study

Completed

Drug Details

Intervention Type
DRUG
Total Trials
64