Success Metrics

Clinical Success Rate
75.0%

Based on 69 completed trials

Completion Rate
75%(69/92)
Active Trials
118(47%)
Results Posted
88%(61 trials)
Terminated
23(9%)

Phase Distribution

Ph phase_3
43
17%
Ph phase_1
71
28%
Ph not_applicable
5
2%
Ph early_phase_1
3
1%
Ph phase_4
3
1%
Ph phase_2
118
47%

Phase Distribution

74

Early Stage

118

Mid Stage

46

Late Stage

Phase Distribution243 total trials
Early Phase 1First-in-human
3(1.2%)
Phase 1Safety & dosage
71(29.2%)
Phase 2Efficacy & side effects
118(48.6%)
Phase 3Large-scale testing
43(17.7%)
Phase 4Post-market surveillance
3(1.2%)
N/ANon-phased studies
5(2.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

64.5%

69 of 107 finished

Non-Completion Rate

35.5%

38 ended early

Currently Active

118

trials recruiting

Total Trials

250

all time

Status Distribution
Active(130)
Completed(69)
Terminated(38)
Other(13)

Detailed Status

Completed69
Active, not recruiting62
Recruiting56
Terminated23
Withdrawn15
unknown12

Development Timeline

Analytics

Development Status

Total Trials
250
Active
118
Success Rate
75.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (1.2%)
Phase 171 (29.2%)
Phase 2118 (48.6%)
Phase 343 (17.7%)
Phase 43 (1.2%)
N/A5 (2.1%)

Trials by Status

completed6928%
active_not_recruiting6225%
unknown125%
recruiting5622%
suspended10%
terminated239%
not_yet_recruiting125%
withdrawn156%

Recent Activity

Clinical Trials (250)

Showing 20 of 250 trialsScroll for more
NCT04722146Phase 1

A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Active Not Recruiting
NCT06287944Phase 1

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Recruiting
NCT05438043Phase 3

A Study of Daratumumab

Active Not Recruiting
NCT06768489Phase 1

A Study of JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide or in Combination With Pomalidomide for Multiple Myeloma

Recruiting
NCT07072585Phase 2

Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL)

Not Yet Recruiting
NCT06413498Phase 3

A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

Active Not Recruiting
NCT03899155Phase 2

Pan Tumor Rollover Study

Recruiting
NCT07335887Phase 2

Sonrotoclax Plus Dexamethasone With or Without Daratumumab Regimen in Patients With t(11;14) Primary AL Amyloidosis

Recruiting
NCT04140162Phase 2

Phase 2 Study With Minimal Residual Disease (MRD) Driven Adaptive Strategy in Treatment for Newly Diagnosed Multiple Myeloma (MM) With Upfront Daratumumab-based Therapy

Active Not Recruiting
NCT07728188Phase 3

A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma

Not Yet Recruiting
NCT04827979Phase 1

Daratumumab and Belatacept for Desensitization

Completed
NCT04973605Phase 1

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

Recruiting
NCT06615479Phase 3

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

Recruiting
NCT05083169Phase 3

A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma

Active Not Recruiting
NCT06892522Phase 1

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations

Recruiting
NCT07555938Phase 3

Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

Recruiting
NCT06042725Phase 1

MC210808 Venetoclax in Combination With Lenalidomide and Dexamethasone (Ven-Rd), Daratumumab and Dexamethasone (Ven-Dd), or Daratumumab-Lenalidomide-Dexamethasone (Ven-DRd) for the Treatment of Multiple Myeloma

Recruiting
NCT07341867Phase 1

Systemic Anti-Cancer Therapy Dose Modifications for Individuals With Duffy Null Phenotype

Not Yet Recruiting
NCT02343042Phase 1

Selinexor and Backbone Treatments of Multiple Myeloma Patients

Recruiting
NCT07649525Phase 3

Personalising Treatment for Myeloma Patients Based on Initial Response to NHS Treatment and Their Overall Fitness Level

Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
250