Success Metrics

Clinical Success Rate
73.9%

Based on 68 completed trials

Completion Rate
74%(68/92)
Active Trials
124(49%)
Results Posted
93%(63 trials)
Terminated
24(9%)

Phase Distribution

Ph phase_2
120
47%
Ph early_phase_1
3
1%
Ph not_applicable
5
2%
Ph phase_4
4
2%
Ph phase_1
71
28%
Ph phase_3
45
18%

Phase Distribution

74

Early Stage

120

Mid Stage

49

Late Stage

Phase Distribution248 total trials
Early Phase 1First-in-human
3(1.2%)
Phase 1Safety & dosage
71(28.6%)
Phase 2Efficacy & side effects
120(48.4%)
Phase 3Large-scale testing
45(18.1%)
Phase 4Post-market surveillance
4(1.6%)
N/ANon-phased studies
5(2.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

63.6%

68 of 107 finished

Non-Completion Rate

36.4%

39 ended early

Currently Active

124

trials recruiting

Total Trials

255

all time

Status Distribution
Active(136)
Completed(68)
Terminated(39)
Other(12)

Detailed Status

Completed68
Active, not recruiting64
Recruiting60
Terminated24
Withdrawn15
Not yet recruiting12

Development Timeline

Analytics

Development Status

Total Trials
255
Active
124
Success Rate
73.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (1.2%)
Phase 171 (28.6%)
Phase 2120 (48.4%)
Phase 345 (18.1%)
Phase 44 (1.6%)
N/A5 (2.0%)

Trials by Status

recruiting6024%
active_not_recruiting6425%
completed6827%
not_yet_recruiting125%
unknown125%
terminated249%
withdrawn156%

Recent Activity

Clinical Trials (255)

Showing 20 of 255 trialsScroll for more
NCT04925193Phase 2

Personalized Selinexor-based Therapy for Relapsed/Refractory Multiple Myeloma

Active Not Recruiting
NCT05898646Phase 2

Daratumumab Maintenance Therapy for Improving Survival in Patients With Light Chain Amyloidosis, EMILIA Trial

Recruiting
NCT07391657Phase 3

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

Recruiting
NCT07222761Phase 3

A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

Recruiting
NCT06055075Phase 1

A Study Evaluating Safety, Tolerability, and Clinical Activity of Forimtamig-Based Treatment Combinations in Participants With Relapsed or Refractory Multiple Myeloma

Terminated
NCT04973605Phase 1

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

Recruiting
NCT04181827Phase 3

A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma

Active Not Recruiting
NCT04722146Phase 1

A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Active Not Recruiting
NCT05438043Phase 3

A Study of Daratumumab

Active Not Recruiting
NCT05623020Phase 3

A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant

Recruiting
NCT05083169Phase 3

A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma

Active Not Recruiting
NCT07665450Phase 3

A Study of Ramantamig Plus Daratumumab Versus Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone (DVRd) or Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With NDMM For Whom Stem Cell Transplant is Not Planned

Recruiting
NCT04108195Phase 1

A Study of Subcutaneous Daratumumab Regimens in Combination With Bispecific T Cell Redirection Antibodies for the Treatment of Participants With Multiple Myeloma

Active Not Recruiting
NCT05250973Phase 2

A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis

Active Not Recruiting
NCT07393282Phase 3

A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM)

Recruiting
NCT05572229Phase 2

Study of Teclistamab in Combination in Elderly Patients With Multiple Myeloma

Active Not Recruiting
NCT04133636Phase 2

A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma

Active Not Recruiting
NCT06768489Phase 1

A Study of JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide for Multiple Myeloma, Newly Diagnosed AL Amyloidosis, and High-risk Smoldering Multiple Myeloma or JNJ-79635322 in Combination With Pomalidomide for Multiple Myeloma

Recruiting
NCT05455320Phase 3

A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment

Active Not Recruiting
NCT05552222Phase 3

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
255