Success Metrics

Clinical Success Rate
100.0%

Based on 8 completed trials

Completion Rate
100%(8/8)
Active Trials
0(0%)
Results Posted
0%(0 trials)

Phase Distribution

Ph phase_3
2
18%
Ph phase_2
1
9%
Ph phase_1
8
73%

Phase Distribution

8

Early Stage

1

Mid Stage

2

Late Stage

Phase Distribution11 total trials
Phase 1Safety & dosage
8(72.7%)
Phase 2Efficacy & side effects
1(9.1%)
Phase 3Large-scale testing
2(18.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

72.7%

8 of 11 finished

Non-Completion Rate

27.3%

3 ended early

Currently Active

0

trials recruiting

Total Trials

11

all time

Status Distribution
Completed(8)
Terminated(3)

Detailed Status

Completed8
Withdrawn3

Development Timeline

Analytics

Development Status

Total Trials
11
Active
0
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 18 (72.7%)
Phase 21 (9.1%)
Phase 32 (18.2%)

Trials by Status

withdrawn327%
completed873%

Recent Activity

0 active trials
Showing 5 of 11
completedphase_1

Relative Bioavailability Trial of Dapivirine Ring-004 and Ring-008

NCT05416021
completedphase_1

Pharmacokinetic Study of the Dapivirine Vaginal Ring in Lactating Women

NCT02808949
withdrawnphase_2

Reversing the Epidemic in Africa With Choices in HIV Prevention (REACH)

NCT03074786
completedphase_1

Male Tolerance Study of Dapivirine Gel Following Multiple Topical Penile Exposures

NCT01277640
completedphase_1

DDI Potential: Dapivirine Vaginal Ring and Miconazole Nitrate

NCT01731574
View all 11 trials

Clinical Trials (11)

Showing 11 of 11 trials
NCT05416021Phase 1

Relative Bioavailability Trial of Dapivirine Ring-004 and Ring-008

Completed
NCT02808949Phase 1

Pharmacokinetic Study of the Dapivirine Vaginal Ring in Lactating Women

Completed
NCT03074786Phase 2

Reversing the Epidemic in Africa With Choices in HIV Prevention (REACH)

Withdrawn
NCT01277640Phase 1

Male Tolerance Study of Dapivirine Gel Following Multiple Topical Penile Exposures

Completed
NCT01731574Phase 1

DDI Potential: Dapivirine Vaginal Ring and Miconazole Nitrate

Completed
NCT01337570Phase 3

A Safety and Efficacy Trial of Dapivirine Vaginal Ring in Africa

Withdrawn
NCT01337583Phase 3

A Safety and Efficacy Trial of Dapivirine Vaginal Ring in Africa

Withdrawn
NCT00917904Phase 1

An Expanded Safety Study of Dapivirine Gel 4789 in Africa

Completed
NCT00917891Phase 1

An Expanded Safety Study of Dapivirine Gel 4759 in Africa

Completed
NCT01071174Phase 1

A Safety Study of Dapivirine Vaginal Ring in Africa

Completed
NCT01144676Phase 1

A Safety Study to Assess the Delivery of Dapivirine From a Matrix Vaginal Ring

Completed

All 11 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
11