Success Metrics

Clinical Success Rate
83.5%

Based on 81 completed trials

Completion Rate
84%(81/97)
Active Trials
32(23%)
Results Posted
67%(54 trials)
Terminated
16(11%)

Phase Distribution

Ph phase_1
17
12%
Ph phase_2
73
52%
Ph not_applicable
5
4%
Ph phase_4
1
1%
Ph phase_3
44
31%

Phase Distribution

17

Early Stage

73

Mid Stage

45

Late Stage

Phase Distribution140 total trials
Phase 1Safety & dosage
17(12.1%)
Phase 2Efficacy & side effects
73(52.1%)
Phase 3Large-scale testing
44(31.4%)
Phase 4Post-market surveillance
1(0.7%)
N/ANon-phased studies
5(3.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

83.5%

81 of 97 finished

Non-Completion Rate

16.5%

16 ended early

Currently Active

32

trials recruiting

Total Trials

140

all time

Status Distribution
Active(32)
Completed(81)
Terminated(16)
Other(11)

Detailed Status

Completed81
Recruiting17
Terminated16
Active, not recruiting15
unknown11

Development Timeline

Analytics

Development Status

Total Trials
140
Active
32
Success Rate
83.5%
Most Advanced
Phase 4

Trials by Phase

Phase 117 (12.1%)
Phase 273 (52.1%)
Phase 344 (31.4%)
Phase 41 (0.7%)
N/A5 (3.6%)

Trials by Status

terminated1611%
active_not_recruiting1511%
completed8158%
unknown118%
recruiting1712%

Recent Activity

Clinical Trials (140)

Showing 20 of 140 trialsScroll for more
NCT03407144Phase 2

Safety and Efficacy of Pembrolizumab (MK-3475) in Children and Young Adults With Classical Hodgkin Lymphoma (MK-3475-667/KEYNOTE-667)

Active Not Recruiting
NCT05675410Phase 3

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Recruiting
NCT03907488Phase 3

Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

Active Not Recruiting
NCT07847359Phase 2

Cryoablation Combined With Hepatic Arterial Infusion of Iparomlimab and Tuvonralimab (QL1706), Intravenous Dacarbazine, and Oral Lenvatinib in Patients With Liver Metastases From Malignant Melanoma: a Single-arm, Phase II, Prospective Trial

Recruiting
NCT03233347Phase 2

Doxorubicin, Vinblastine, Dacarbazine, Brentuximab Vedotin, and Nivolumab in Treating Patients With Stage I-II Hodgkin Lymphoma

Active Not Recruiting
NCT03517137Phase 2

Very Early PET-response Adapted Targeted Therapy for Advanced Hodgkin Lymphoma: a Single -Arm Phase II Study

Active Not Recruiting
NCT06745076Phase 2

Personalized Reduction of Chemotherapy Intensity Through ctDNA Evaluation for the Treatment of Patients With Advanced Hodgkin Lymphoma

Recruiting
NCT07551583Phase 2

Phase II Study Of Nivolumab Plus AVD In Pediatric, Adolescent, And Young Adult Patients With CHL

Recruiting
NCT07275216Phase 2

Pembrolizumab in Combination With Chemotherapy for the Treatment of Frail Hodgkin Lymphoma Patients Ineligible for Standard Treatment

Recruiting
NCT05922904Phase 2

PET Adapted Brentuximab Vedotin and Pembrolizumab in Combination With Doxorubicin and Dacarbazine in Classic Hodgkin Lymphoma

Active Not Recruiting
NCT06743126Phase 3

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

Recruiting
NCT06164275Phase 2

Pembrolizumab Followed by Chemotherapy for the Treatment of Patients With Classical Hodgkin Lymphoma

Active Not Recruiting
NCT04685616Phase 3

Brentuximab Vedotin in Early Stage Hodgkin Lymphoma

Recruiting
NCT04727242Phase 2

CytoreductiveSurgery & HIPEC w/Gemcitabine+Chemotherapy w/Dacarbazine in Uterine Leiomyosarcoma

Completed
NCT01868451Not Applicable

Brentuximab Vedotin Combined With AVD Chemotherapy in Patients With Newly Diagnosed Early Stage, Unfavorable Risk Hodgkin Lymphoma

Completed
NCT00600496Phase 1

A Phase I, Open-Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD6244 (ARRY-142886)

Completed
NCT01476410Phase 2

Brentuximab Vedotin and Combination Chemotherapy in Treating Older Patients With Previously Untreated Stage II-IV Hodgkin Lymphoma

Completed
NCT05404945Phase 2

Fitness-adapted, Pembrolizumab-based Therapy for Untreated Classical Hodgkin Lymphoma Patients 60 Years of Age and Above

Active Not Recruiting
NCT06377566Phase 2

A Study of BV-AVD in People With Bulky Hodgkin Lymphoma

Recruiting
NCT06563245Phase 2

Brentuximab Vedotin for Newly Diagnosed cHL in Chinese CAYA Based on PET/CT Assessment

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
140