Success Metrics

Clinical Success Rate
81.9%

Based on 481 completed trials

Completion Rate
82%(481/587)
Active Trials
171(19%)
Results Posted
57%(276 trials)
Terminated
106(12%)

Phase Distribution

Ph early_phase_1
4
0%
Ph phase_4
21
2%
Ph phase_3
163
18%
Ph not_applicable
32
3%
Ph phase_1
295
32%
Ph phase_2
398
43%

Phase Distribution

299

Early Stage

398

Mid Stage

184

Late Stage

Phase Distribution913 total trials
Early Phase 1First-in-human
4(0.4%)
Phase 1Safety & dosage
295(32.3%)
Phase 2Efficacy & side effects
398(43.6%)
Phase 3Large-scale testing
163(17.9%)
Phase 4Post-market surveillance
21(2.3%)
N/ANon-phased studies
32(3.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.3%

481 of 630 finished

Non-Completion Rate

23.7%

149 ended early

Currently Active

171

trials recruiting

Total Trials

918

all time

Status Distribution
Active(191)
Completed(481)
Terminated(149)
Other(97)

Detailed Status

Completed481
Terminated106
Recruiting103
unknown97
Active, not recruiting68
Withdrawn43

Development Timeline

Analytics

Development Status

Total Trials
918
Active
171
Success Rate
81.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.4%)
Phase 1295 (32.3%)
Phase 2398 (43.6%)
Phase 3163 (17.9%)
Phase 421 (2.3%)
N/A32 (3.5%)

Trials by Status

terminated10612%
completed48152%
active_not_recruiting687%
not_yet_recruiting172%
unknown9711%
withdrawn435%
recruiting10311%
enrolling_by_invitation30%

Recent Activity

Clinical Trials (918)

Showing 20 of 918 trialsScroll for more
NCT03150693Phase 3

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Recruiting
NCT07763210Phase 2

Intrathecal Cytarabine and Hydrocortisone for the Early Treatment of ICANS in Patients Undergoing CAR T Therapy for Non Hodgkin Lymphoma

Recruiting
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT02981628Phase 2

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT05554419Phase 2

Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)

Not Yet Recruiting
NCT06917911Phase 2

Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial)

Recruiting
NCT03914625Phase 3

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

Active Not Recruiting
NCT02203526Phase 1

Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib,Rituximab (TEDDI-R) in Primary CNS Lymphoma

Active Not Recruiting
NCT06377540Phase 2

MT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin Lymphoma

Recruiting
NCT03418038Phase 2

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

Recruiting
NCT05554393Phase 2

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT05453903Phase 1

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

Active Not Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT01511562Phase 2

Combination Chemotherapy With or Without Autologous Stem Cell Transplant in Treating Patients With Central Nervous System B-Cell Lymphoma

Completed
NCT02392429Phase 2

FLT PET/CT in Measuring Response in Patients With Previously Untreated Acute Myeloid Leukemia

Active Not Recruiting
NCT05645718Phase 2

Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia

Recruiting
NCT07507760Phase 2

Oral Decitabine Plus Ivosidenib as First Line for Older/Unfit Adult AML Patients

Recruiting
NCT03182244Phase 3

A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase 3 (FLT3) Mutation

Completed
NCT05554406Phase 2

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
918