Success Metrics

Clinical Success Rate
81.8%

Based on 476 completed trials

Completion Rate
82%(476/582)
Active Trials
168(18%)
Results Posted
58%(275 trials)
Terminated
106(12%)

Phase Distribution

Ph phase_4
21
2%
Ph not_applicable
30
3%
Ph phase_2
395
43%
Ph early_phase_1
4
0%
Ph phase_3
162
18%
Ph phase_1
295
32%

Phase Distribution

299

Early Stage

395

Mid Stage

183

Late Stage

Phase Distribution907 total trials
Early Phase 1First-in-human
4(0.4%)
Phase 1Safety & dosage
295(32.5%)
Phase 2Efficacy & side effects
395(43.6%)
Phase 3Large-scale testing
162(17.9%)
Phase 4Post-market surveillance
21(2.3%)
N/ANon-phased studies
30(3.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.2%

476 of 625 finished

Non-Completion Rate

23.8%

149 ended early

Currently Active

168

trials recruiting

Total Trials

912

all time

Status Distribution
Active(189)
Completed(476)
Terminated(149)
Other(98)

Detailed Status

Completed476
Terminated106
Recruiting100
unknown97
Active, not recruiting68
Withdrawn43

Development Timeline

Analytics

Development Status

Total Trials
912
Active
168
Success Rate
81.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.4%)
Phase 1295 (32.5%)
Phase 2395 (43.6%)
Phase 3162 (17.9%)
Phase 421 (2.3%)
N/A30 (3.3%)

Trials by Status

terminated10612%
recruiting10011%
active_not_recruiting687%
completed47652%
suspended10%
unknown9711%
withdrawn435%
enrolling_by_invitation30%
not_yet_recruiting182%

Recent Activity

Clinical Trials (912)

Showing 20 of 912 trialsScroll for more
NCT04047641Phase 1

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Recruiting
NCT04546399Phase 2

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT04214249Phase 2

BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia

Active Not Recruiting
NCT04190550Phase 1

Testing the Addition of an Anti-cancer Drug, Navtemadlin, to the Usual Treatments (Cytarabine and Idarubicin) in Patients With Acute Myeloid Leukemia

Active Not Recruiting
NCT05554393Phase 2

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT06917911Phase 2

Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial)

Recruiting
NCT05886049Phase 1

A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease

Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT05554406Phase 2

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Recruiting
NCT03983824Phase 1

Testing the Addition of an Anti-cancer Drug, M3814, to the Usual Treatment (Mitoxantrone, Etoposide, and Cytarabine) for Relapsed or Refractory Acute Myeloid Leukemia

Active Not Recruiting
NCT07636564Phase 2

Testing Blinatumomab With or Without Revumenib in Patients With B-cell Acute Lymphoblastic Leukemia With a Genetic Change Requiring More Treatment

Not Yet Recruiting
NCT04158739Phase 1

Flotetuzumab for the Treatment of Pediatric Recurrent or Refractory Acute Myeloid Leukemia

Active Not Recruiting
NCT07490288Not Applicable

Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML

Recruiting
NCT07604233Phase 1

Phase 1/2 FLAG-IDA, VEN and Asciminib in CML and Ph+ AML

Not Yet Recruiting
NCT03586609Phase 2

Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine in Treating Patients With Previously Untreated Acute Myeloid Leukemia

Recruiting
NCT01661881Phase 2

Rituximab/Bendamustine + Rituximab/Cytarabine for Mantle Cell Lymphoma

Active Not Recruiting
NCT05453903Phase 1

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

Active Not Recruiting
NCT04848974Phase 1

Uproleselan, Cladribine, and Low Dose Cytarabine for the Treatment of Patients With Treated Secondary Acute Myeloid Leukemia

Completed
NCT02981628Phase 2

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
912