Success Metrics

Clinical Success Rate
81.8%

Based on 478 completed trials

Completion Rate
82%(478/584)
Active Trials
169(18%)
Results Posted
58%(276 trials)
Terminated
106(12%)

Phase Distribution

Ph phase_1
295
32%
Ph early_phase_1
4
0%
Ph phase_4
21
2%
Ph phase_3
163
18%
Ph phase_2
397
43%
Ph not_applicable
31
3%

Phase Distribution

299

Early Stage

397

Mid Stage

184

Late Stage

Phase Distribution911 total trials
Early Phase 1First-in-human
4(0.4%)
Phase 1Safety & dosage
295(32.4%)
Phase 2Efficacy & side effects
397(43.6%)
Phase 3Large-scale testing
163(17.9%)
Phase 4Post-market surveillance
21(2.3%)
N/ANon-phased studies
31(3.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.2%

478 of 627 finished

Non-Completion Rate

23.8%

149 ended early

Currently Active

169

trials recruiting

Total Trials

916

all time

Status Distribution
Active(191)
Completed(478)
Terminated(149)
Other(98)

Detailed Status

Completed478
Terminated106
Recruiting100
unknown97
Active, not recruiting69
Withdrawn43

Development Timeline

Analytics

Development Status

Total Trials
916
Active
169
Success Rate
81.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.4%)
Phase 1295 (32.4%)
Phase 2397 (43.6%)
Phase 3163 (17.9%)
Phase 421 (2.3%)
N/A31 (3.4%)

Trials by Status

active_not_recruiting698%
enrolling_by_invitation30%
completed47852%
terminated10612%
unknown9711%
suspended10%
recruiting10011%
not_yet_recruiting192%
withdrawn435%

Recent Activity

Clinical Trials (916)

Showing 20 of 916 trialsScroll for more
NCT05554393Phase 2

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Recruiting
NCT05554406Phase 2

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

Recruiting
NCT07131059Not Applicable

MRD-positive AML Clinical Study

Recruiting
NCT03147612Phase 2

Low-Intensity Chemotherapy, Ponatinib and Blinatumomab in Treating Patients With Philadelphia Chromosome-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT07754799Phase 2

A Randomized Phase II Selection Trial of Venetoclax-Based Induction Intensity in Newly Diagnosed Acute Myeloid Leukemia

Not Yet Recruiting
NCT06390319Phase 2

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

Recruiting
NCT07490288Not Applicable

Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML

Recruiting
NCT06265545Not Applicable

Multicenter, Platform-type Clinical Study of Refractory/Recurrent Acute Myeloid Leukemia

Recruiting
NCT06744504Phase 3

Standard-dose vs Intermediate-dose Cytarabine Induction in the Treatment of Acute Myeloid Leukemia With RUNX1-RUNX1T1

Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT02203526Phase 1

Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib,Rituximab (TEDDI-R) in Primary CNS Lymphoma

Active Not Recruiting
NCT02835222Phase 2

Selinexor With Combination With Induction/Consolidation Therapy in Acute Myeloid Leukemia Patients

Active Not Recruiting
NCT07223814Phase 3

Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)

Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT03150693Phase 3

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Recruiting
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT02003222Phase 3

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT06177067Phase 1

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Recruiting
NCT02971397Phase 1

Cytarabine and Daunorubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Completed
NCT04530565Phase 3

Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
916