Success Metrics

Clinical Success Rate
81.9%

Based on 471 completed trials

Completion Rate
82%(471/575)
Active Trials
166(18%)
Results Posted
58%(272 trials)
Terminated
104(11%)

Phase Distribution

Ph phase_1
294
32%
Ph phase_2
392
43%
Ph not_applicable
30
3%
Ph phase_3
162
18%
Ph phase_4
21
2%
Ph early_phase_1
4
0%

Phase Distribution

298

Early Stage

392

Mid Stage

183

Late Stage

Phase Distribution903 total trials
Early Phase 1First-in-human
4(0.4%)
Phase 1Safety & dosage
294(32.6%)
Phase 2Efficacy & side effects
392(43.4%)
Phase 3Large-scale testing
162(17.9%)
Phase 4Post-market surveillance
21(2.3%)
N/ANon-phased studies
30(3.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.5%

471 of 616 finished

Non-Completion Rate

23.5%

145 ended early

Currently Active

166

trials recruiting

Total Trials

908

all time

Status Distribution
Active(190)
Completed(471)
Terminated(145)
Other(102)

Detailed Status

Completed471
Terminated104
Recruiting101
unknown100
Active, not recruiting65
Withdrawn41

Development Timeline

Analytics

Development Status

Total Trials
908
Active
166
Success Rate
81.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.4%)
Phase 1294 (32.6%)
Phase 2392 (43.4%)
Phase 3162 (17.9%)
Phase 421 (2.3%)
N/A30 (3.3%)

Trials by Status

enrolling_by_invitation20%
not_yet_recruiting222%
terminated10411%
recruiting10111%
withdrawn415%
suspended20%
unknown10011%
active_not_recruiting657%
completed47152%

Recent Activity

Clinical Trials (908)

Showing 20 of 908 trialsScroll for more
NCT07490288Not Applicable

Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML

Not Yet Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT05554393Phase 2

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Recruiting
NCT03418038Phase 2

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

Recruiting
NCT07032727Phase 2

Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations

Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT05849662Phase 1

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

Recruiting
NCT05886049Phase 1

Testing the Addition of an Anti-cancer Drug, SNDX-5613, to the Standard Chemotherapy Treatment (Daunorubicin and Cytarabine) for Newly Diagnosed Patients With Acute Myeloid Leukemia That Has Changes in NPM1 or MLL/KMT2A Gene

Recruiting
NCT01424982Phase 2

Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT06001788Phase 1

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Recruiting
NCT06034470Phase 1

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

Active Not Recruiting
NCT04216524Phase 2

Venetoclax, SL-401, and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm

Recruiting
NCT05554406Phase 2

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Recruiting
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT06561152Phase 1

Tagraxofusp and Low-Intensity Chemotherapy for CD123-Positive Relapsed or Refractory AML

Recruiting
NCT05554419Phase 2

Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)

Not Yet Recruiting
NCT05955261Phase 2

A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients With Acute Myeloid Leukemia

Suspended
NCT04530565Phase 3

Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

Active Not Recruiting
NCT00792948Phase 2

Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT03983824Phase 1

Testing the Addition of an Anti-cancer Drug, M3814, to the Usual Treatment (Mitoxantrone, Etoposide, and Cytarabine) for Relapsed or Refractory Acute Myeloid Leukemia

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
908